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Dataset results
17 results for “fecal metabolite”
Fecal glucocorticoid metabolite levels of American pika (Ochotona princeps) and habitat characteristics of their associated territories found in rock glaciers adjacent to Niwot Ridge and within Rocky Mountain National Park, 2018 - 2019.
To understand whether stress-associated hormones vary with metrics of habitat quality, we measured fecal glucocorticoid metabolite (FGM) levels in the American pika (Ochotona princeps), a small mammal with well-defined habitat (talus), that can vary in quality depending on the presence of rock ice features (RIFs). In 2018, we sampled pika scat from two types of RIFs: “active” rock glaciers thought to harbor subsurface ice recently, and “fossil” rock glaciers considered long devoid of subsurface ice (as classified by Janke 2005, 2007). Specifically, fecal pellets were collected from pika territories located in rock glaciers within eight sites along the Front Range of Colorado: four in Rocky Mountain National Park (2 active, 2 fossil) and four adjacent to Niwot Ridge (2 active, 2 fossil) (pika_fecal_glu_rg.aw.csv). To account for possible seasonal variation in pika FGM, scat samples were collected in the alpine spring and fall. To understand other influences of habitat quality on FGMs, we also measured fine-scale habitat differences between rock glaciers in 2019, including talus depth, clast size, and land cover metrics related to forage (pika_fecal_habitat_rg.aw.csv).
Fecal and Blood Metabolites of Pigs
<p>The experimental design of the animal study and the sanitary challenge model used have been described by Van der Meer et al. (2020). Pigs were divided into high sanitary condition (HSC) or to low sanitary condition (LSC), for details please see the original publication by Van der Meer et al. (2020). At the dissection day, three pigs per room were euthanized to collect blood and digesta samples for further analysis. We used colon digesta and blood samples from pigs in this study that received a diet with a basal amino acid (AA) ratios (indicated as “diet AA-B” in the paper of van der Meer et al. 2020) and a protein content of CP 168 g/kg; LSC (n=18) and HSC (n=18). </p> <p>These samples were analyzed by Nuclear Magnetic Resonance (NMR) and by Triple Quad Mass Spectrometry (TQMS). The details of these laboratory analysis are described in the journal article entitled "Sanitary conditions affect the colonic microbiome and the colonic and systemic metabolome of female pigs" (doi: will update accordingly). The data uploaded here are by the format of the Joint Committee on Atomic and Molecular Physical Data (JCAMP). Moreover the metadata file shows the link between the samples and their corresponding group, i.e. HSC or LSC, and other characteristics.</p>
Ensminger et al 2020 - Fecal glucocorticoid metabolites in harvested elk
<p>Raw data for modeling fecal glucocorticoid metabolites in Ensminger et al. 2020.</p>
16S And WGS Feature Tables: Tryptophan Metabolites And Their Predicted Microbial Sources In Fecal Samples Of Healthy Individuals
<p>The zip file contains 16S and WGS feature tables used in the following publication:</p> <p>Tryptophan Metabolites And Their Predicted Microbial Sources In Fecal Samples Of Healthy Individuals<br>Cynthia L. Chappell, Kristi L. Hoffman, Philip L. Lorenzi, Lin Tan, Joseph F. Petrosino, Richard A. Gibbs, Donna M. Muzny, Harsha Doddapaneni, Matthew C. Ross, Vipin K. Menon, Anil Surathu, Sara J. Javornik Cregeen, Anaid G. Reyes, Pablo C. Okhuysen bioRxiv 2023.12.20.572622; doi: https://doi.org/10.1101/2023.12.20.572622</p>
Effects of Dietary Fructose on Gut Microbiota and Fecal Metabolites in Obese Men and Postmenopausal Women: A Pilot Study
ClinicalTrials.gov study NCT03339245. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Blood cortisol and fecal cortisol metabolite concentrations following an ACTH challenge in unanesthetized brown bears (Ursus arctos)
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Data from: Meerkat close calling patterns are linked to sex, social category, season and wind, but not fecal glucocorticoid metabolite concentrations
It is well established that animal vocalizations can encode information regarding a sender's identity, sex, age, body size, social rank and group membership. However, the association between physiological parameters, particularly stress hormone levels, and vocal behavior is still not well understood. The cooperatively breeding African meerkats (Suricata suricatta) live in family groups with despotic social hierarchies. During foraging, individuals emit close calls that help maintain group cohesion. These contact calls are acoustically distinctive and variable in rate across individuals, yet, information on which factors influence close calling behavior is missing. The aim of this study was to identify proximate factors that influence variation in call rate and acoustic structure of meerkat close calls. Specifically, we investigated whether close calling behavior is associated with sex, age and rank, or stress hormone output (i.e., measured as fecal glucocorticoid metabolite (fGCM) concentrations) as individual traits of the caller, as well as with environmental conditions (weather) and reproductive seasonality. To disentangle the effects of these factors on vocal behavior, we analyzed sound recordings and assessed fGCM concentrations in 64 wild but habituated meerkats from 9 groups during the reproductive and non-reproductive seasons. Dominant females and one-year old males called at significantly higher rates compared to other social categories during the reproductive season. Additionally, dominant females produced close calls with the lowest mean fundamental frequencies (F0) and the longest mean pulse durations. Windy conditions were associated with significantly higher call rates during the non-reproductive season. FGCM concentrations were unrelated to close calling behavior. Our findings suggest that meerkat close calling behavior conveys information regarding the sex and social category of the caller, but shows no association with fGCM concentrations. The change in call rate in response to variation in the social and ecological environments individuals experience indicates some degree of flexibility in vocal production.
Association Between Fecal Microbiota Composition, Metabolite Concentrations, and Indoxyl Sulfate Levels
ClinicalTrials.gov study NCT06877585. IPD Sharing: YES. Countries: 1. Publications: 29.
Characterization of Disease Related Changes in Inflammatory Bowel Disease Using Fecal Metabolite Profiling
ClinicalTrials.gov study NCT01666717. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Fecal corticosterone metabolite levels in two closely related rodent species in a sub-Mediterranean environment
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Data from: Meerkat close calling patterns are linked to sex, social category, season and wind, but not fecal glucocorticoid metabolite concentrations
Open the record for dataset details and reuse information.
Data from: Fecal cortisol metabolites to assess stress in wildlife: evaluation of a field method in free ranging chamois
1. Non-invasive faecal cortisol metabolite (FCM) analysis is a well-established tool to quantify stress in captive and free-ranging species. While the method has great potential, its suitability in field studies might be limited when faecal samples from unknown individuals are used. Possible factors affecting final results and thus jeopardizing correct data interpretation are individual and sex-specific variation, storage conditions and uneven distribution of metabolites in the faeces. 2. We tested these factors on a population of free-ranging Alpine chamois Rupicapra rupicapra rupicapra in the Austrian Alps. Faecal samples (n = 183) were analysed with an established enzyme immunoassay (EIA). To further validate the assay for FCM in chamois, a high-performance liquid chromatography (HPLC) was performed. Sex-specific differences in metabolite excretion were evaluated. Effects of storage length and temperature on FCM were tested with two experiments. The distribution of metabolites in the faeces was determined by the analysis of subsamples of single faecal samples. Potential individual effects on FCM levels and individually variable reactions to stressful events were evaluated with a simulation experiment. 3. Patterns of immunoreactive peaks after HPLC separation were similar for different faecal samples, except in one sample of a male. In the stability tests, storage time at ambient temperature prior to freezing and the individual were the most important variables in modulating FCM. Concentrations within single samples varied significantly between pellets. Analysis of faecal samples collected from June to October showed a highly significant seasonal trend (P < 0·001) and a considerable variance of FCM levels within the population. Simulations confirmed that individual reactions to stressors in terms of varying gradients and FCM levels can explain the observed FCM patterns. 4. Using FCM to assess adrenocortical function requires measuring extensively metabolized products of glucocorticoids, whose excretion and detection in faeces depend on several environmental, endogenous and methodological factors. In free-ranging wildlife, these factors and the intrinsic individual differences in FCM excretion generate systemic noise and substantially distort final results. Therefore, sampling of unknown individuals inevitably jeopardizes meaningful interpretation of data, if the above named factors are not taken into consideration.
Ingestion Effect of Formula Milk With Triple Bifidobacteria Strains on Fecal Quality and Metabolites in Healthy Children
ClinicalTrials.gov study NCT06044376. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Fecal cortisol metabolites to assess stress in wildlife: evaluation of a field method in free ranging chamois
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Fecal microbiota transplantation from young donor mice rejuvenates hematopoietic stem cell in aged recipients by suppressing inflammatory signals while modulating gut microbiota and metabolites
GEO Series GSE201920. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Diet and Stool Metabolites in Fecal Incontinence
ClinicalTrials.gov study NCT02485522. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Correlation of Fecal Microbiome and Its Metabolites With Outcome of Radiotherapy in Head and Neck Carcinoma
ClinicalTrials.gov study NCT05156177. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.