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ShareScore release 0.9.0
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3 results for “fimh”
Binding site plasticity regulation of the FimH catch-bond mechanism: Molecular Dynamics dataset
<p>Dataset of Molecular Dynamics simulations and analysis scripts used in the article "Binding site plasticity regulation of the FimH catch-bond mechanism" [<a href="https://doi.org/10.1016/j.bpj.2023.05.029">paper</a>][<a href="https://doi.org/10.1101/2022.11.15.516604">bioRxiv</a>].</p> <p>Contains:</p> <ul> <li>Replica Exchange with Solute Scaling (REST2) simulations of the FimH protein lectin domain in its two main allosteric states (Associated and Separated), in presence and absence of its synthetic ligand heptyl α-ᴅ-mannose (input files and trajectories of the unscaled replicas)</li> <li>Replica Exchange Umbrella Sampling (REUS) simulations of the liganted systems along a collective variable (CV) describing binding site opening (input files and trajectories)</li> <li>REUS simulations in presence of a pulling force on the protein-ligand complex.</li> </ul> <p>See the article for more details.</p>
A Study of a FimH Blocker, EB8018, in Crohn's Disease Patients
ClinicalTrials.gov study NCT03709628. IPD Sharing: Not stated. Countries: 4. Publications: 0.
Antibodies to FimH in Anti-neutrophil cytoplasmic antibody - associated vasculitis
<p>Peptide microarray containing 4216 unique peptides from 88 different microorganisms represented by validated B-cell epitopes selected from the Immune Epitope Database (<a href="http://www.iedb.org">http://www.iedb.org</a>). A total of 1509 bacterial, 2311 viral, 12 fungal and 384 protozoal epitopes were printed on the arrays. This array was probed with serum from 8 patients with ANCA-associated vasculitis collected at presentation with the disease as well as in remission and analysed for binding by IgM and IgG.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.