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datasets available to search
ShareScore release 0.9.0
Dataset results
33 results for “gastrointestinal infections”
The repurposing of tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug resistant Shigella spp.
<p><strong>dataset for The repurposing of tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug resistant <em>Shigella</em> spp.</strong></p> <p>Elena Fernández Alvaro <sup>1*</sup>, Phat Voong Vinh <sup>2</sup>, Cristina de Cozar <sup>1</sup>, David Wille <sup>1</sup>, Beatriz Urones <sup>1</sup>,</p> <p>Alan Price <sup>1</sup>, Nhu Tran Do Hoang <sup>2</sup>, Tuyen Ha Thanh <sup>2</sup>, Molly McCloskey <sup>3</sup>, Shareef Shaheen<sup> 3</sup>, Denise Dayao<sup> 4</sup>, Jaime de Mercado <sup>1</sup>, Pablo Castañeda <sup>1</sup>, Adolfo García-Perez <sup>1</sup>, Benson Singa <sup>5</sup>, Patricia Pavlinac <sup>6</sup>,</p> <p>Judd Walson<sup>3</sup>, Maria Santos Martínez-Martínez <sup>1</sup>, Samuel L.M. Arnold <sup>3</sup>, Tzipori Saul <sup>4</sup>, Lluis Ballell <sup>1#</sup>,</p> <p>and Stephen Baker <sup>7,8*</sup></p> <p> </p>
Dataset of host, habitat and vegetation parameters in relation to gastrointestinal parasite infections of small mammalian hosts in Madagascar
<p>The dataset contains information on the endoparasite infection status of 903 individuals of four small mammal species (<em>Microcebus murinus</em>, <em>M. ravelobensis</em>, <em>Eliurus myoxinus</em>, <em>Rattus rattus</em>) in relation to host-specific (sex, body condition, population density) and habitat-specific factors (degree of habitat fragmentation, fragment size, distance to the edge of the fragment, percentage of edge habitat, vegetation structure).</p>
Fig. 2 in Patterns of gastrointestinal parasite infections in bighorn sheep, Ovis canadensis, with respect to host sex and seasonality
Fig. 2. Seasonal differences in fecal egg counts in female (blue) and male (red) bighorn sheep. Point intervals display the mean count ±95% confidence intervals as predicted by generalised linear mixed effects models. Seasons are: Late gestation (Late gestation/early lactation between April to June); Lactation/summer (between July and October); Rut (November and December); Winter (Winter/early gestation from January to March). Parasites are a) Strongyle; b) Nematodirus; c) Marshallagia; d) Protostrongylus lungworm; e) Eimeria. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 1 in Patterns of gastrointestinal parasite infections in bighorn sheep, Ovis canadensis, with respect to host sex and seasonality
Fig. 1. Schematic of the reproductive biology and seasons of bighorn sheep. The blue circle represents the entire year, where the top is December, 3 o'clock March, 6 o'clock June, 10 o'clock October etc. The grey quarter circle represents the season Jan–March = Winter/early gestation; the dark green quarter circles represent the season from April–June = late gestation/early lactation; the light green line represents the season between July and October, which is also representing lactation/summer; and the brown line is representing November and December, or the rutting season. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 3 in Patterns of gastrointestinal parasite infections in bighorn sheep, Ovis canadensis, with respect to host sex and seasonality
Fig. 3. Differences in mean and standard error in strongyle counts between males that use the coursing or tending mating tactic. Point intervals display the mean count ±95% confidence intervals as predicted by the generalised linear mixed effects model.
Data from: Nasopharyngeal microbiome profiles in rural Venezuelan children are associated with respiratory and gastrointestinal infections
<p>Background: Recent research suggests that the microbiota affects susceptibility to both respiratory tract infections (RTIs) and gastrointestinal infections (GIIs). In order to optimize global treatment options, it is important to characterize microbiota profiles across different niches and geographic/socioeconomic areas where RTI and GII prevalences are high.</p> <p>Methods: We performed 16S sequencing of nasopharyngeal swabs from 209 Venezuelan Amerindian children aged 6 weeks–59 months who were participating in a 13-valent pneumococcal conjugate vaccine (PCV13) study. Using random forest models, differential abundance testing, and regression analysis, we determined whether specific bacteria were associated with RTIs or GIIs and variation in PCV13 response.</p> <p>Results: Microbiota compositions differed between children with or without RTIs (P = .018) or GIIs (P = .001). Several species were associated with the absence of infections. Some of these health-associated bacteria are also observed in developed regions, such as Corynebacterium (log2(fold change [FC]) = 3.30 for RTIs and log2(FC) = 1.71 for GIIs), while others are not commonly observed in developed regions, such as Acinetobacter (log2(FC) = 2.82 and log2(FC) = 5.06, respectively). Klebsiella spp. presence was associ- ated with both RTIs (log2(FC) = 5.48) and GIIs (log2(FC) = 7.20).</p> <p>Conclusions: The nasopharyngeal microbiota of rural Venezuelan children included several bacteria that thrive in tropical humid climates. Interestingly, nasopharyngeal microbiota composition not only differed in children with an RTI but also in those with a GII, which suggests a reciprocal interplay between the 2 environments. Knowledge of region-specific microbiota patterns enables tailoring of preventive and therapeutic approaches.</p>
Tranexamic Acid to Reduce Infection After Gastrointestinal Surgery
ClinicalTrials.gov study NCT04192435. IPD Sharing: YES. Countries: 1. Publications: 2.
Viral Respiratory and Gastrointestinal Infections in Children Under 6 Years of Age
ClinicalTrials.gov study NCT00987519. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Determining the Worldwide Epidemiology of Surgical Site Infections After Gastrointestinal Surgery
ClinicalTrials.gov study NCT02662231. IPD Sharing: YES. Countries: 1. Publications: 15.
Parasitic Infections of the Gastrointestinal Tract
ClinicalTrials.gov study NCT00001162. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Efficacy of a 2'-Fucosylactose-based Food Supplement on the Prevention of Respiratory and Gastrointestinal Infections.
ClinicalTrials.gov study NCT07050693. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Data from: Nasopharyngeal microbiome profiles in rural Venezuelan children are associated with respiratory and gastrointestinal infections
Open the record for dataset details and reuse information.
Data from: Physiological and social consequences of gastrointestinal nematode infection in a nonhuman primate
Gastrointestinal nematodes are intensely studied models for host-pathogen interactions in wildlife, yet consequences of infections are not fully understood. Among the potential costs of nematode infection are physiological changes caused by immune system activation, reduction or reallocation of available energy, as well as potential social consequences in terms of decreased social activity or avoidance of infected individuals. We used experimental anthelmintic treatment to investigate effects of strongyle nematode infection in Barbary macaques (Macaca sylvanus), comparing 56 treated to 17 untreated individuals. Deworming success was monitored by coproscopy and infection probability estimated from patch occupancy models. Increasing strongyle infection probabilities were associated with increased fecal glucocorticoid metabolite levels and slightly decreased activity, and had no significant effect on energy balance quantified as urinary C-peptide levels. The frequency to approach into close spatial proximity of a partner was predicted by the partner's, but not focal individual's infection status, with a tendency towards infected individuals being approached less frequently. Although effects were weak, they suggest a co-occurrence of sickness and avoidance behavior, both possibly shaping social interaction patterns with potential consequences for an individual's social relationships. This study adds to the growing body of research on the complex interactions of sociality, health and fitness in a group living species.
Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants
ClinicalTrials.gov study NCT01249911. IPD Sharing: Not stated. Countries: 0. Publications: 15.
Incidence of Hospitalizations for Serious Infections in Patients Receiving Biologic Anti-Inflammatories for Rheumatologic, Psoriatic, and Gastrointestinal Conditions: A Descriptive Analysis
ClinicalTrials.gov study NCT02922192. IPD Sharing: YES. Countries: 0. Publications: 1.
Gastrointestinal Complications in Association With Oropharyngeal and Respiratory Infections in Mechanical Ventilation
ClinicalTrials.gov study NCT03267693. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Safety and Efficacy of Niclosamide in Patients With COVID-19 With Gastrointestinal Infection
ClinicalTrials.gov study NCT04858425. IPD Sharing: NO. Countries: 3. Publications: 0.
Data from: Physiological and social consequences of gastrointestinal nematode infection in a nonhuman primate
Open the record for dataset details and reuse information.
Dual RNA-seq reveals a type 6 secretion system-dependent blockage of TNF-alpha signaling and BicA as a Burkholderia pseudomallei virulence factor important during gastrointestinal infection
GEO Series GSE201263. Rattus norvegicus. 15 samples. Type: Expression profiling by high throughput sequencing.
Probiotic and Prebiotic Supplementation of Antiretroviral Therapy Improves Gastrointestinal Immunity in SIV-infected Macaques
GEO Series GSE42232. Homo sapiens; Macaca nemestrina. 8 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.