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79 results for “gatekeeper”

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zenodo40/100

HGDM - the Hysteretic and Gatekeeping Depressions Model

<p>The Hysteretic and Gatekeeping Depressions Model simulates the variable contributing fractions of Canadian Prairie basins.<br> These files will include the model code as well as data files used to develop and test the model.</p> <p>&nbsp;</p>

opencc-by-4.0Sep 2022View details →
zenodo40/100

Data Related to Osorio-Forero, Foustoukos, Cardis et al., "Noradrenergic locus coeruleus activity functionally partitions NREMS to gatekeep the NREM-REM cycle"

<p>This Zenodo Upload contains the Transparent Data Files for an updated version of the manuscript currently published in Nature Neuroscience</p> <p>and entitled&nbsp;</p> <p><em>'</em>Infraslow noradrenergic locus coeruleus activity fluctuations control are gatekeepers of the NREM&ndash;REM sleep cycle' &nbsp; </p> <p>published by the authors as indicated in the author list.</p>

opencc-by-4.0Nov 2024View details →
zenodo36/100

04 Stela of Maati, gatekeeper

Stela of Maati, gatekeeper (Dynasty 11) Middle Kingdom. Metropolitan Museum of Art, New York. Source: Objaverse 1.0 / Sketchfab

opencc-byApr 2019View details →
ClinicalTrials.gov36/100

Increasing Help-Seeking Behavior Among Transitioning Veterans at Risk for Suicide With Online Gatekeeper Training

ClinicalTrials.gov study NCT04565951. IPD Sharing: NO. Countries: 1. Publications: 1.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov32/100

Evaluating AI-Gatekeeper Software in Coronary Artery Stenosis Screening: a Multicenter RCT

ClinicalTrials.gov study NCT06178900. IPD Sharing: NO. Countries: 1. Publications: 7.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov32/100

Implementation of a Suicide Prevention Gatekeeper Program in the University Setting

ClinicalTrials.gov study NCT07052240. IPD Sharing: YES. Countries: 1. Publications: 7.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov32/100

Magnetic Resonance Adenosine Perfusion Imaging as Gatekeeper of Invasive Coronary Intervention

ClinicalTrials.gov study NCT02580851. IPD Sharing: Not stated. Countries: 1. Publications: 2.

restrictedIPD-UNDECIDEDFeb 2026View details →
zenodo28/100

Calpain DEK1 acts as a developmental switch gatekeeping cell fate transitions

<p>This is the supplementary data archive for our study showing that:</p> <p><em><strong>Calpain DEK1 acts as a developmental switch gatekeeping cell fate transitions</strong></em></p> <p><strong>Abstract:</strong> Calpains are cysteine proteases that control cell fate transitions. Although calpains are viewed as modulatory proteases displaying severe, pleiotropic phenotypes in eukaryotes, human calpain targets are also directed to the N-end rule degradatory pathway. Several of these destabilized targets are transcription factors, hinting at a gene regulatory role. Here, we analyze the gene regulatory networks of <em>Physcomitrium</em> <em>patens</em> and characterize the regulons that are deregulated in <em>DEK1</em> calpain mutants. Predicted cleavage patterns of regulatory hierarchies in the five DEK1-controlled subnetworks are consistent with the gene&rsquo;s pleiotropy and the regulatory role in cell fate transitions targeting a broad spectrum of functions. Network structure suggests DEK1-gated sequential transition between cell fates in 2D to 3D development. We anticipate that both our method combining phenotyping, transcriptomics and data science to dissect phenotypic traits and our model explaining the calpain&rsquo;s role as a switch gatekeeping cell fate transitions will inform biology beyond plant development.</p>

openSep 2021View details →
geo24/100

The mediator subunit Med23 serves as a gatekeeper of the myeloid-primed state of hematopoietic stem cells (RNA-Seq)

GEO Series GSE112358. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2018View details →
geo24/100

RIF1 acts as a gatekeeper of B cell identity during late differentiation

GEO Series GSE237560. Mus musculus. 29 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2024View details →
geo24/100

Molecular gatekeepers: how peptide maturation molecules coordinate cell-cell communication in Streptococcus pneumoniae

GEO Series GSE268602. Streptococcus pneumoniae. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo24/100

Dipeptidyl peptidase DPF-3 is a gatekeeper of microRNA Argonaute compensation in animals

GEO Series GSE276186. Caenorhabditis elegans. 18 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenMar 2025View details →
geo24/100

HMGA1 acts as an epigenetic gatekeeper of ASCL2 and Wnt signaling during colon tumorigenesis [RNA-seq]

GEO Series GSE279070. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

EGR1 is a gatekeeper of inflammatory enhancers in human macrophages

GEO Series GSE136216. Homo sapiens. 42 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.

openGEO-OpenJan 2020View details →
geo24/100

AP-1 is a temporally regulated dual gatekeeper of reprogramming to pluripotency (RNA-Seq)

GEO Series GSE121052. Mus musculus; Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2021View details →
geo24/100

yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [mouse]

GEO Series GSE115670. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2019View details →
geo24/100

Molecular gatekeepers balancing differentiation and maintenance of human male germline stem cells uncovered by single cell resolution analysis

GEO Series GSE153947. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2021View details →
geo24/100

A gatekeeper mechanism of the noradrenergic neural control of tear secretion via the NA-Adra1a-Ucp2 pathway

GEO Series GSE224484. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2025View details →
geo24/100

A Single Trophoblast Layer Acts as the Gatekeeper at the Endothelial-Hematopoietic Crossroad in the Placenta

GEO Series GSE163286. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo24/100

Calhm6: A Gatekeeper of Macrophage Plasticity and Immune Response [Raw264.7-OE]

GEO Series GSE249905. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2026View details →

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record