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70 results for “gene rearrangement”
Figure 1 in Mitochondrial gene rearrangement within genus Gasteruption (Hymenoptera: Evanioidea: Gasteruptiidae)
Figure 1. Gene rearrangement in the Gasteruption spp. mitochondrial genomes. The red line shows reversal of gene. The black line shows translocation of gene. Translocation of trnN occurred between Gasteruption sp. and G. parvicollarium.
Fig. 5 in The complete mitochondrial genome of Platygaster robiniae (Hymenoptera: Platygastridae): A novel tRNA secondary structure, gene rearrangements and phylogenetic implications
Fig. 5. Phylogenetic tree Note: (A): Maximum likelihood (ML) phylogenetic tree inferred from the mitochondrial genome based on the 13 PCGs dataset; (B): Bayesian inference (BI) phylogenetic tree inferred from the mitochondrial genome based on the 13 PCGs dataset.
Fig. 4 in The complete mitochondrial genome of Platygaster robiniae (Hymenoptera: Platygastridae): A novel tRNA secondary structure, gene rearrangements and phylogenetic implications
Fig. 4. Mitochondrial genome organization of Platygaster robiniae and 11 species of Platygastroidea, compared with the ancestral pancrustacean mt genome organization. Note: tRNA genes are indicated by single letter amino acid codes, L1, L2, S1 and S2 denote tRNALeu(CUN), tRNALeu(UUR), tRNASer(AGN) and tRNASer(UCN), respectively. Genes are transcribed from left to right except those indicated by underlining. Gene movements, relative to the ancestral organization, are indicated with arrows.
Fig. 2 in The complete mitochondrial genome of Platygaster robiniae (Hymenoptera: Platygastridae): A novel tRNA secondary structure, gene rearrangements and phylogenetic implications
Fig. 2. Amino acids (A) and relative synonymous codons (B) of protein-coding genes of the mitochondrial genome of Platygaster robiniae.
Fig. 1 in The complete mitochondrial genome of Platygaster robiniae (Hymenoptera: Platygastridae): A novel tRNA secondary structure, gene rearrangements and phylogenetic implications
Fig. 1. Genetic map of the complete mitochondrial genome of Platygaster robiniae. Notes: the blue arrow represents the direction of gene transcription; the black peak represents the deviation of GC%; the purple and green peaks represent the deviation in GC skew; green refers to positive skew, and purple indicates negative skew. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Inter-generational nuclear crosstalk links the control of gene expression to programmed genome rearrangements during the Paramecium sexual cycle
<p>Multinucleate cells are found in many eukaryotes, but how multiple nuclei coordinate their functions is still poorly understood. In the cytoplasm of the ciliate <em>Paramecium tetraurelia</em>, two micronuclei (MIC) serving sexual reproduction coexist with a somatic macronucleus (MAC) dedicated to gene expression. During sexual processes, the MAC is progressively destroyed while still ensuring transcription and new MACs develop from copies of the zygotic MIC. Several gene clusters are successively induced and switched off before vegetative growth resumes. Concomitantly, programmed genome rearrangements (PGR) remove transposons and their relics from the new MACs. Development of the new MACs is controlled by the old MAC, since the latter expresses genes involved in PGR, including the <em>PGM</em> gene encoding the essential PiggyMac endonuclease that cleaves the ends of eliminated sequences. Using RNA deep sequencing and transcriptome analysis, we show that impairing PGR up-deregulates key PGR genes, together with ~600 other genes possibly also involved in PGR. Among these genes, 42% are no longer induced when no new MACs are formed, including 180 genes that are co-expressed with <em>PGM </em>under all tested conditions. We propose that bi-directional crosstalk between the two coexisting generations of MACs links gene expression to the progression of MAC development.</p>
Alignments used for the phylogenies in "Caryophylliids (Anthozoa, Scleractinia) have a mitochondrial gene rearrangement: lesson learned from mitochondrial and nuclear phylogenomics"
<p>"mitochondrial_caryotree.phy": concatenated alignment of mitochondrial data in phylip format; "mitochondrial_caryotree.partitions.txt": indication of start/stop positions of each partition in the mitochondrial data alignment; "nuclear_caryotree_55taxa-50p.phylip": alignment of nuclear exons and ultraconserved elements in phylip format.</p>
Fig. 4 in The complete mitochondrial genome of Platygaster robiniae (Hymenoptera: Platygastridae): A novel tRNA secondary structure, gene rearrangements and phylogenetic implications
Fig. 4. (continued).
Fig. 3 in The complete mitochondrial genome of Platygaster robiniae (Hymenoptera: Platygastridae): A novel tRNA secondary structure, gene rearrangements and phylogenetic implications
Fig. 3. The secondary structure of 22 tRNA in Platygaster robiniae.
Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement
ClinicalTrials.gov study NCT02828358. IPD Sharing: UNDECIDED. Countries: 4. Publications: 1.
Data from: Chromosomal rearrangements do not seem to affect the gene flow in hybrid zones between karyotypic races of the common shrew (Sorex araneus)
Chromosomal rearrangements are proposed to promote genetic differentiation between chromosomally differentiated taxa and therefore promote speciation. Due to their remarkable karyotypic polymorphism, the shrews of the Sorex araneus group were used to investigate the impact of chromosomal rearrangements on gene flow. Five intraspecific chromosomal hybrid zones characterized by different levels of karyotypic complexity were studied using 16 microsatellites markers. We observed low levels of genetic differentiation even in the hybrid zones with the highest karyotypic complexity. No evidence of restricted gene flow between differently rearranged chromosomes was observed. Contrary to what was observed at the interspecific level, the effect of chromosomal rearrangements on gene flow was undetectable within the S. araneus species.
Figure 2 in Molecular phylogeny of Acanthochitonina (Mollusca: Polyplacophora: Chitonida): three new mitochondrial genomes, rearranged gene orders and systematics
Figure 2. Molecular phylogeny of Acanthochitonina. Majority-rule consensus tree from the Bayesian analysis of the multilocus nucleotide data set, which includes three mitochondrial and two nuclear markers. Additional phylogenetic results are available in the Supplemental File 2. Note the proposed taxonomic arrangements shown by vertical lines. Numbers at nodes are support values from posterior probabilities and maximum likelihood bootstrap proportions, respectively. Scale bar is in substitutions per site.
Figure 1 in Molecular phylogeny of Acanthochitonina (Mollusca: Polyplacophora: Chitonida): three new mitochondrial genomes, rearranged gene orders and systematics
Figure 1. Phylogenetic relationships and gene arrangements of available chiton mitochondrial genomes. Majority-rule consensus tree from the Bayesian analysis of the mitochondrial genome nucleotide data set (outgroup taxa is omitted for simplicity). Identical topologies were recovered from all other analyses of mitochondrial genome data sets (see main text). Numbers at nodes are posterior probabilities and maximum likelihood bootstrap proportions, respectively. Scale bar is in substitutions per site. Mitochondrial gene orders of Haliotis rubra (Gastropoda), Octopus vulgaris (Cephalopoda) and Solemya velum (Bivalvia) are shown for comparison. Genes encoded by the minus strand are underlined; rearranged genes are highlighted in red (translocations) and green (changes of coding strands).
Novel mitochondrial gene rearrangements pattern in the millipede Polydesmus sp. GZCS-2019 and phylogenetic analysis of the Myriapoda
<p>Novel mitochondrial gene rearrangements pattern in the millipede <em>Polydesmus</em> sp. GZCS-2019 and phylogenetic analysis of the Myriapoda-Supplementary Materials</p>
Immunoglobulin Gene Rearrangement and Repair in Healthy Donors
ClinicalTrials.gov study NCT04889573. IPD Sharing: NO. Countries: 1. Publications: 1.
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
ClinicalTrials.gov study NCT02568267. IPD Sharing: YES. Countries: 16. Publications: 9.
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
ClinicalTrials.gov study NCT04065399. IPD Sharing: NO. Countries: 11. Publications: 6.
Data from: Chromosomal rearrangements do not seem to affect the gene flow in hybrid zones between karyotypic races of the common shrew (Sorex araneus)
Open the record for dataset details and reuse information.
Pinometostat With Standard Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and MLL Gene Rearrangement
ClinicalTrials.gov study NCT03724084. IPD Sharing: YES. Countries: 1. Publications: 0.
Futibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements
ClinicalTrials.gov study NCT04093362. IPD Sharing: NO. Countries: 20. Publications: 0.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.