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24
datasets available to search
ShareScore release 0.9.0
Dataset results
24 results for “gliclazide”
Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers
ClinicalTrials.gov study NCT04198948. IPD Sharing: YES. Countries: 1. Publications: 9.
Comparative Efficacy and Safety of Sitagliptin Phosphate Combined with Gliclazide Sustained-Release Tablets Versus Metformin in Treatment-Naïve Patients with Type 2 Diabetes Mellitus and Glucotoxicity: A Single-Center, Prospective, Randomized Controlled Non-Inferiority Study
<p>This dataset supports the manuscript titled "Comparative Efficacy and Safety of Sitagliptin Phosphate Combined with Gliclazide Sustained-Release Tablets Versus Metformin in Treatment-Naïve Patients with Type 2 Diabetes Mellitus and Glucotoxicity: A Single-Center, Prospective, Randomized Controlled Non-Inferiority Study." The study aims to compare the efficacy and safety of sitagliptin phosphate combined with gliclazide sustained-release tablets against metformin in treatment-naïve patients with type 2 diabetes mellitus and glucotoxicity. Data include clinical measurements, laboratory test results, and adverse event records collected throughout the trial period. Statistical analyses were conducted to assess non-inferiority between the two treatment groups. This dataset provides valuable insights for researchers interested in diabetes management, pharmacotherapy, and randomized controlled trials.</p>
A Study of the Safety and Efficacy of Glimepiride, Gliclazide, Repaglinide or Acarbose When Added to Sitagliptin + Metformin Combination Therapy in Chinese Participants With Diabetes (MK-0431-313)
ClinicalTrials.gov study NCT01709305. IPD Sharing: YES. Countries: 0. Publications: 1.
Efficacy Comparison of Polyethylene Glycol Loxenatide and Gliclazide on the Brain Function in T2DM Patients
ClinicalTrials.gov study NCT06217887. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Study of Combination Therapy of Gliclazide MR and Basal Insulin Versus Insulin Monotherapy to Treat Type 2 Diabetes
ClinicalTrials.gov study NCT00736515. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Observational Study of Effectiveness and Tolerability of Gliclazide MR 60mg in Diabetic Patients Fasting During RAMADAN
ClinicalTrials.gov study NCT04132934. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Sulphonylurea Receptor Mutation and Responsiveness to Gliclazide - a Pilot Proof of Concept, Randomised Cross-over Study
ClinicalTrials.gov study NCT02201602. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Vildagliptin Compared to Gliclazide as Dual Therapy With Metformin in Muslim Patients With Type 2 Diabetes Fasting During Ramadan
ClinicalTrials.gov study NCT01758380. IPD Sharing: Not stated. Countries: 16. Publications: 2.
Efficacy and Safety of Vildagliptin Compared to Gliclazide in Drug Naive Patients With Type 2 Diabetes
ClinicalTrials.gov study NCT00102388. IPD Sharing: Not stated. Countries: 2. Publications: 3.
Real-world Clinical Effectiveness and Patient Insight Associated With Adding Sodium Glucose Co-transporter 2 Inhibitor to Gliclazide Modified Release
ClinicalTrials.gov study NCT06708091. IPD Sharing: NO. Countries: 1. Publications: 1.
Application of sulfur and nitrogen doped carbon quantum dots as sensitive fluorescent nanosensors for the determination of saxagliptin and gliclazide
<p>In this study, highly fluorescent sulfur and nitrogen doped carbon quantum dots (S,N-CQDs) were used as fluorescent nanosensors for direct spectrofluorimetric estimation of each of gliclazide and saxagliptin without any pre-derivatization steps for the first time. S,N-CQDs were synthesized employing a simple hydrothermal technique using citric acid and thiosemicarbazide. The produced S,N-CQDs were characterized using different techniques including fluorescence emission spectroscopy, UV spectrophotometry, high resolution transmission electron microscopy, and FT-IR spectroscopy. Following excitation at 360 nm, S,N-CQDs exhibited a strong emission peak at 430 nm. The native fluorescence of S,N-CQDs was quantitatively enhanced by addition of increased concentrations of the studied drugs. The fluorescence enhancement of S,N-CQDs and the concentrations of the studied drugs revealed a wide linear relationship in the range of 30.0-500.0 μM and 75.0-600.0 µM with limits of detection of 5.0 μM and 10.15 µM for gliclazide and saxagliptin, respectively. The proposed method was efficiently utilized for determination of cited drugs in their commercial tablets with % recoveries ranging from 98.6 to 101.2% and low % RSD values (less than 2%). The mechanism of interaction between S,N-CQDs and the two drugs was studied. Validation of the proposed method was carried out in accordance with ICH guidelines.</p>
Comparison of Repaglinide and Gliclazide in Chinese Subjects With Type 2 Diabetes Never Received Oral Antidiabetic Drug Treatment
ClinicalTrials.gov study NCT01022762. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Clinical Bioequivalence Study on Two Gliclazide 80mg Tablet Formulations
ClinicalTrials.gov study NCT02643329. IPD Sharing: NO. Countries: 1. Publications: 0.
Application of sulfur and nitrogen doped carbon quantum dots as sensitive fluorescent nanosensors for the determination of saxagliptin and gliclazide
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Observational Cohort Study Evaluating the Effectiveness of an Education Program (NGAYDAUTIEN) in Combination With Gliclazide MR in the Management of Uncontrolled Type 2 Diabetic Patients.
ClinicalTrials.gov study NCT06704802. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Dapagliflozin on Vascular Functions in Patients With Type 2 Diabetes Compared to Gliclazide
ClinicalTrials.gov study NCT02610088. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Co-administration of Cabergoline and Gliclazide Improve Glycemic Parameters and Lipid Profile in T2DM Patients
ClinicalTrials.gov study NCT03313661. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Gliclazide in Healthy Volunteers
ClinicalTrials.gov study NCT02777671. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Comparative Study of Sitagliptin and Gliclazide With Metformin in Type 2 Diabetes Patients With Glucotoxicity
ClinicalTrials.gov study NCT06613750. IPD Sharing: Not stated. Countries: 1. Publications: 0.
An Open-randomized, Balanced, Crossover Bioequivalence Study to Compare One MR Tablet of 60 mg Gliclazide and Two MR Tablets of 30 mg Gliclazide in Healthy Subjects
ClinicalTrials.gov study NCT01195532. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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