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15 results for “group II intron”
First unravelling of the hidden and intricate evolutionary history of a bacterial group II intron family
<p>Bacterial group II introns are large RNA enzymes that self-splice from primary transcripts. Following excision, they can invade various DNA target sites using RNA-based mobility pathways. <span>As fast-evolving retromobile elements that move between genetic loci within and across species, their evolutionary history was proved difficult to study and infer. Here we identified several homologs of Ll.LtrB, the model group II intron from <em>Lactococcus lactis</em>, and traced back</span> their evolutionary relationship through phylogenetic analyses. Our data demonstrate that the Ll.LtrB homologs in Lactococci originate from a single and recent lateral transfer event of Ef.PcfG from <em>Enterococcus faecalis</em>. We also show that these <span>introns disseminated in </span>Lactococci <span>following recurrent episodes of independent mobility events in conjunction with occurences of lateral transfer. Our phylogenies identified additional lateral transfer events from the environmental clade of the more diverged Lactococci introns to a series of low GC gram-positive bacterial species including <em>E. faecalis</em>. We also determined that functional intron adaptation occurred early in Lactococci following Ef.PcfG acquisition from <em>E. faecalis </em>and that two of the more diverged Ll.LtrB homologs remain proficient mobile elements despite the significant number of mutations acquired.</span><span> This study describes the first comprehensive </span>evolutionary history of a bacterial group II intron family.</p>
First unravelling of the hidden and intricate evolutionary history of a bacterial group II intron family
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Template switching by a group II intron reverse transcriptase: biochemical analysis and implications for RNA-seq
GEO Series GSE138200. synthetic construct. 11 samples. Type: Other.
NicOPURE: Nickless RNA Circularization and One-Step Purification with Engineered Group II Introns and Cyclizing UTRs
GEO Series GSE246246. Gaussia princeps (in: crustaceans). 6 samples. Type: Other.
Arabidopsis CFM6, a CRM domain protein, is involved in the splicing of mitochondrial group II intron 4 of nad5 and normal plant growth
GEO Series GSE181108. Arabidopsis thaliana. 6 samples. Type: Expression profiling by high throughput sequencing.
Two novel PLS-class pentatricopeptide repeat proteins are involved in the group II intron splicing of mitochondrial transcripts in the moss Physcomitrella patens
GEO Series GSE145050. Physcomitrium patens. 4 samples. Type: Expression profiling by array.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq) [kidney]
GEO Series GSE140097. Mus musculus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq) [Proximal Colon]
GEO Series GSE140100. Mus musculus. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq)
GEO Series GSE140105. Mus musculus. 76 samples. Type: Non-coding RNA profiling by high throughput sequencing.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq) [Distal Colon]
GEO Series GSE140103. Mus musculus. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq) [brain]
GEO Series GSE140099. Mus musculus. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq) [spleen]
GEO Series GSE140095. Mus musculus. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq) [Thymus]
GEO Series GSE140094. Mus musculus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq) [heart]
GEO Series GSE140098. Mus musculus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
AlkB-facilitated RNA methylation sequencing (ARM-seq) and Demethylase-thermostable group II intron RT tRNA sequencing (DM-tRNA-seq) [liver]
GEO Series GSE140096. Mus musculus. 10 samples. Type: Non-coding RNA profiling by high throughput sequencing.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.