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364 results for “health risk”
Health of the Nation. National NCD risk factor survey, Barbados (2012-13)
<p><strong>Executive Summary</strong></p> <div> <div>The Caribbean is experiencing increasing levels of illness and death from non-communicable disease (NCD) causes. Regional leaders pledged to combat this epidemic through increased surveillance and intervention, implementing healthcare policies and programmes across our countries. In Barbados, one of the Ministry of Health (MoH)’s initiatives has been the Health of the Nation (HotN) Survey, to provide information on the prevalence and social determinants of risk factors for lifestyle-related NCD. This will allow identification of potential targets for future interventions to improve prevention and control of these diseases in the Barbadian population. In this comprehensive, cross-sectional survey, data were collected for 1234 participants aged at least 25 years (response rate: 55%) on demographics, behavioural risk factors, medical history, place of treatment and costs incurred, blood pressure and anthropometry, and biochemical measures. The survey sample under-represented young adults (particularly men) and over-represented the elderly (particularly women), so a weighting scheme was utilised to balance the sample distribution for age and sex with that of the Barbados 2010 Census. Prevalence of each risk factor was estimated overall, for each sex separately, and stratified by three broad age-groups.</div> <br> <div>Main findings show that Barbadian adults are at high risk from NCDs due to high prevalence of biological and behavioural risk factors. Most alarming is that two in every three adults in our population (and three-quarters of women) are overweight and/or obese. In addition, more than one in three adults in Barbados (more than one in two of those aged at least 45 years) are hypertensive, and one in five have diabetes (almost one in two of those aged 65 years or older). At least one in three of those with known hypertension or diabetes who were receiving treatment had sub-optimal control. </div> <br> <div>Daily tobacco use was reported by one in 10 men, vs one in 50 women. Harmful alcohol use followed a similar pattern, i.e. was mainly reported by young men, with excessive weekly alcohol consumption over the past 30 days reported by roughly the same proportions of men and women reporting daily tobacco use. One in three men aged 25–44 years reported binge drinking in the past 30 days. Core survey results show that Barbadian residents have low fruit and vegetable consumption, while half of the sample reported low levels of physical activity. About one in four adults had healthcare insurance (one in three of those who were employed). More in-depth information on diet, physical activity and cost/insurance will be provided from the relevant survey sub-studies at a later date. Urgent action is required to address the low levels of healthy behavioural risk and high levels of biological risk present in the Barbadian adult population. Community and civil society involvement could help support healthier behaviours. A multi-sectoral approach is required to combat NCD risk on all levels, with creation of national guidelines to supplement an appropriate regulatory framework within an enabling environment.</div> </div>
Source Data and ambient ozone dataset generated in "Substantially underestimated global health risks of current ozone pollution"
<p>Existing assessments might have underappreciated ozone-related health impacts worldwide. Here our study assesses current global ozone pollution using the high-resolution (0.05°) estimation from a geo-ensemble learning model, with key focuses on population exposure and all-cause mortality burden. Our model demonstrates strong performance, achieving a mean bias of less than -1.5 parts per billion against in-situ measurements. We estimate that 66.2% of the global population is exposed to excess ozone for short term (> 30 days per year), and 94.2% suffers from long-term exposure. Furthermore, severe ozone exposure levels are observed in Cropland areas, particularly over Asia. Importantly, the all-cause ozone-attributable deaths significantly surpass previous recognition from specific diseases worldwide. Notably, mid-latitude Asia (30°N) and the western United States show high mortality burden, contributing substantially to global ozone-attributable deaths. Our study highlights current significant global ozone-related health risks and may benefit the ozone-exposed population in the future.</p>
Risk and symptoms of COVID-19 in health professionals according to baseline immune status and booster vaccination during the Delta and Omicron waves in Switzerland – a multicentre cohort study
<p>For details, see publication</p>
Respondents' perspectives on the impact of digital data-based health services on disaster risk management in Indonesia.
<p>This data contains respondents' perspectives on the impact of digital data-based health services on disaster risk management. Digital health services are the implementation of digital, information, and communication technologies in the context of health services. Digital health services include: mHealth, Health Information Technology, Wearable Devices, Telehealth and Telemedicine, and Personalized Medicine. </p> <p>Data was collected and processed as part of the ODDEA (Overcoming Digital Divide Between Europe and Southeast Asia) EU research project (Project ID: HORIZON MSCA-SE 101086381) would be advisable.</p>
A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy: Summary statistics - Health records
<p>Infectious agents contribute significantly to the global burden of diseases, through both acute infection and their chronic sequelae. We leveraged the UK Biobank to identify genetic loci that influence humoral immune response to multiple infections. From 45 genome-wide association studies in 9,611 participants from UK Biobank, we identified NFKB1 as a locus associated with quantitative antibody responses to multiple pathogens including those from the herpes, retro- and polyoma-virus families. An insertion-deletion variant thought to affect NFKB1 expression (rs28362491), was mapped as the likely causal variant. This variant has persisted throughout hominid evolution and could play a key role in regulation of the immune response. Using 121 infection and inflammation related traits in 487,297 UK Biobank participants, we show that the deletion allele was associated with an increased risk of infection from diverse pathogens but had a protective effect against allergic disease. We propose that altered expression of NFKB1, as a result of the deletion, modulates haematopoietic pathways, and likely impacts cell survival, antibody production, and inflammation. Taken together, we show that disruptions to the tightly regulated immune processes may tip the balance between exacerbated immune responses and allergy, or increased risk of infection and impaired resolution of inflammation. </p> <p>-------------------------------------------------------------------------------------</p> <p>This dataset contains GWAS summary statistics for infection, inflammation, and allergy related traits in 487,297 individuals</p>
Data for The impact of information about tobacco-related reproductive vs. general health risks on South Indian women's tobacco use decisions
<p>Tobacco Intervention Study Mysore India March-April 2016</p> <p>Published version: <a href="https://doi.org/10.1017/ehs.2020.61">https://doi.org/10.1017/ehs.2020.61</a></p>
Disease and lesion maps - part of the Scientific opinion on the evaluation of public and animal health risks in case of a delayed post-mortem inspection in ungulates
<p>EFSA was requested to assess the impact on effectiveness of <em>post-mortem</em> inspection in terms of any change in the sensitivity of detection of animal diseases of domestic and wild ungulates listed according to Article 5 of Regulation (EC) No 2016/429 and septicaemia, pyaemia, toxaemia or viraemia, when carried out after up to 24 hours or up to 72 hours after slaughter in comparison to when it is carried out immediately after slaughter. In order to identify the main lesions associated with the target diseases, a so called “disease map” was built, with the information about the clinical forms of the diseases (acute, subacute, chronic, or latent forms) and clinical signs, as well as potential lesions that could be observed on the respective diseased animals.</p> <p>The following information is indicated for each disease/condition in the disease map:</p> <ol> <li>The susceptible animal species</li> <li>Whether there is any surveillance programme in place in the EU</li> <li>The signs associated with the disease that could be detected at <em>ante mortem </em>inspection;</li> <li>The lesions associated with the disease that could be detected at <em>post mortem</em> inspection</li> <li>The probability of detecting the disease during the PMI as normally carried out.</li> <li>Whether carcass swabbing and/or laboratory tests are normally carried out.</li> </ol> <p>From the disease map, the list of organs to be considered at <em>post mortem</em> inspection and the lesions, a “lesion map” was built by connecting animal species with organs, lesions and corresponding disease. This was done to facilitate the construction of a questionnaire where, for each organ and the five types of lesions, the respondents (meat inspectors) had to provide a numerical answer about how many carcasses out of 100 with the given lesion, will be still detected after 24- or 72-h of refrigerated storage.</p>
A Tool for Uncertainty Quantification in Reconstructing Sparse Water Quality Time Series Data to Assess Risk Metrics for Watershed Health and TMDL Analysis
<p>The uploaded file contains the input and output data which can be used to reproduce the results in the research article 'Uncertainty Quantification in Reconstruction of Sparse Water Quality Time Series: Implications for Watershed Health and Risk-Based TMDL Assessment'. Please refer to the file '<a href="https://zenodo.org/api/files/31b59cce-8eb2-4ee7-93aa-61474c6f6359/dst_2019_SJRW_TP_TDS.zip?versionId=2af2b54d-d5fb-4720-919d-de2e827595e2">dst_2019_SJRW_TP_TDS.zip'</a> for updated files..</p>
EFSA Opinion Update of risks for animal health related to the presence of ochratoxin A (OTA) in feed: Annexes on Occurrence data in feed submitted to EFSA
<p>Annexes to EFSA's Update Opinion on the risks for animal health related to the presence of OTA in feed. Annex B includes the occurrence data in feed extracted from EFSA Data Warehouse for the period from 2012 to 2021. Annex C contains the occurrence data expressed in dry matter following analysis and cleansing of the dataset as detailed in EFSA's Opinion. Annex D lists the samples of 'Compound feed' and other feed materials except forage expressed in whole weight. The number of samples across some of the feed categories differ among the two annex C and D because in few cases the moisture content was not reported (and no assumption on the moisture could be done), precluding the conversion of the analytical results to either whole weight or dry matter. </p>
Measuring the risk of violence through health surveillance.
<p>database used for the study "M<span>easuring the risk of violence through health surveillance" to be published.</span></p>
Assessment of Potential Risk Factors for COVID-19 among Health Care Workers in a Health Care Setting in Delhi, India
<p><strong><em>Executive summary</em></strong></p> <p>The novel coronavirus SARS-CoV2 (COVID-19), first detected by Wuhan Municipal Health Commission, China, in Wuhan, Hubei Province in December 2020 and eventually the disease became pandemic. It was declared as Public Health Emergency of International Concern (PHEIC) by WHO in January 2020. The COVID-19 disease primarily spreads through droplets of saliva or discharge from the nose when an infected person coughs or sneezes. People infected with the COVID-19 virus experiences mild, moderate or serious respiratory illness. </p> <p>Health workers play a critical role in the clinical management of patients with COVID-19 and hence are likely to be the most vulnerable for contracting the disease. Therefore, investigating the extent of infection in health care settings and identifying risk factors for infection among health workers along with follow-up within a facility in which a confirmed case of COVID-19 infection is receiving care can provide useful information on virus transmissibility and routes of transmission, and will bear important step in limiting amplification events in health care facilities. </p> <p> </p> <p><strong>Objectives:</strong></p> <p>1. To find out the extent of human-to-human transmission of the SARS-CoV-2 infection among health workers<br> 2. To study the clinical presentations of COVID-19 infection and the risk factors for infection among health workers.<br> 3 To evaluate the effectiveness of infection prevention and control measures among health workers in protecting against COVID-19.<br> 4. To evaluate the effectiveness of infection prevention and control programmes at health facility level <br> 5. To determine the serological response of health workers with symptomatic and possibly asymptomatic COVID-19 infection.</p> <p> </p> <p><strong>Materials and Methods:</strong></p> <p>This was a prospective cohort study conducted over a period of seven months, from December 2020 to June 2021, the period covering India’s deadly second wave of COVID-19 pandemic. This was done among the health care workers working in HIMSR & HAHC hospital, a tertiary health care setting (Dedicated COVID-19 Hospital) providing care to patients with a laboratory-confirmed COVID-19 infection. This hospital located in South East Delhi has 200 bedded COVID-19 Care Hospital and 1050 registered healthcare workers who come in contact with COVID-19-infected persons. The study population (sampling frame) included all the health personnel like doctors, nurses, paramedical staff, housekeeping staff, security staff, students of medical, nursing and paramedical sciences and other front office staff who come in contact with the patients. In this study, the first visit / interview (Baseline) was done when the staff came in contact with a confirmed COVID-19 case. The second visit / interview (Endline) was done between 22-28 days. During each of these two visits, biological sample in the form of serum was collected to check the presence of anti-COVID-19 antibodies</p> <p> </p> <p><strong>Results:</strong></p> <p>A total of 192 HCW were recruited in this study. All of them were interviewed and blood was collected for serology at the baseline visit as well as at endline. Out of 192 participants, 119 (61.97%) were detected with SARS-CoV2 antibodies at baseline whereas 73 (38.02%) were seronegative. Again, on22-28 days of follow-up, the seropositivity was 77.7% at the endline. We found that seropositivity was significantly and negatively associated with doctor as profession [OR:0.353, CI:0.176-0.710], COVID-19 symptoms [OR:0.210, CI:0.054-0.820], comorbidities [OR:0.139 , CI: 0.029 - 0.674], recent IPC Training [OR:0.250, CI:0.072 -0.864] , while positively associated with Partially [OR:3.303,CI: 1.256-8.685], as well as fully Vaccinated for COVID-19 [OR:2.428, CI:1.118-5.271]. We also observed seroconversion among 36.7% while 64.0% had increase in titre of antibodies during our follow-up period. The seroconversion was 63.2% in doctors, 42.9% in nurses and 13.0% in paramedics staff. Seroconversion was positively associated with doctor as profession [OR:11.43, CI:2.47 - 52.79] and with partially, as well as fully vaccinated for COVID-19 [OR: 32.63, CI: 5.11 - 208.49]. None of the HCW who were smokers and with any comorbidity did not found to have been seroconversion. We observe a negative and significant relationship of increase in titre of antibodies with recent any ILI symptoms [OR:0.17, 0.13 - 0.94], smokers[OR: 0.35, 95%CI: 0.13 - 0.94], HCW with comorbidities [OR:0.08,95CI: 0.01 - 0.71],, recent full IPC Training [OR:0.07, CI:0.01 -0.63] , while positively associated with partially [OR: 7.87, 95CI: 2.18 - 28.40)], as well as fully Vaccinated for COVID-19 [OR: 3.59, 95CI: 1.46 - 8.87]. Majority of the health care worker enrolled in our study had close contact exposure with COVID-19 patients while 5 had indirect exposure. It was observed that almost all (100% in both) doctors and nurses as well as almost all paramedical staff (99%) were wearing some kind of personal protective equipment (PPE) when they were exposed to a COVID-19 patient. We did not found adherences to any of the infection prevention measure adopted by the enrolled HCW during the recent contact with COVID-19 patients to be significantly associated with seroconversion. </p> <p><strong>Conclusion:</strong></p> <p>Majority of the health care worker (67% doctor, 80% nurses & 55% paramedics) enrolled in our study had close contact exposure with COVID-19 patient. The results show that among 192 HCW enrolled, 62% were seropositive at the baseline. At end line the seropositivity was increased to 77.7%. The seroconversion rate was also studied. It was found to be 36.7% in our study population (63.2% in doctors, 42.9% in nurses and 13.0% in paramedic’s staff.). Adherence to the recommended IPC measures was reported by most participants. About two third (63%) of the HCW in our study were not vaccinated against COVID-19; nurses and paramedics were higher in proportion among those who were unvaccinated. Fifteen percentage were partially vaccinated and 22% were fully vaccinated against COVID-19, with doctors comprising majority among them. We also found that vaccination had the strongest association with seropositivity, seroconversion as well as serial rise of titre.</p>
Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry
<p>These are a collection of EWAS summary statistics for the following publication:</p> <p>Deng Wei Q, Cawte Nathan, Campbell Natalie, Azab Sandi M, de Souza Russell J, Lamri Amel, Morrison Katherine M, Atkinson Stephanie A, Subbarao Padmaja, Turvey Stuart E, Moraes Theo J, Teo Koon K, Mandhane Piush, Azad Meghan B, Simons Elinor, Pare Guillaume, Anand Sonia S (2024) Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry eLife 13:RP93260, https://doi.org/10.7554/eLife.93260.3</p> <p>1. CHILD_450K_R1_March2024_mateversmk_Regression_CpGWide.csv</p> <p>Maternal smoking using ever definition in CHILD (HM450K array).</p> <p>2. CHILD_450K_R1_March2024_matsmoke_Regression_CpGWide.csv</p> <p>Maternal smoking using current smoking definition in CHILD (HM450K array).</p> <p>3. CHILD_450K_R1_March2024_mblsmkexp_Regression_CpG_Wide.csv</p> <p>Maternal smoking exposure (hours per week) in CHILD (HM450K array).</p> <p>4. FAMILY_EPIC_R1_March2024_mateversmk_Regression_CpGWide.csv</p> <p>Maternal smoking using ever definition in FAMILY (customized EPIC array).</p> <p>5. FAMILY_EPIC_R1_March2024_matsmoke_Regression_CpGWide.csv</p> <p>Maternal smoking using current smoking definition in FAMILY (customized EPIC array).</p> <p>6. FAMILY_EPIC_R1_March2024_mblsmkexp_Regression_CpG_Wide.csv</p> <p>Maternal smoking exposure (hours per week) in FAMILY (customized EPIC array).</p> <p>7. START_450K_R1_March2024_mblsmkexp_Regression_CpG_Wide.csv</p> <p>Maternal smoking exposure (hours per week) in START (HM450K array).</p> <p>8. mateversmk_meta_annot_R1.csv</p> <p>Meta-analyzed european EWAS of maternal smoking using ever definition.</p> <p>9. matsmoke_meta_annot_R1.csv</p> <p>Meta-analyzed european EWAS of maternal smoking using current smoking definition.</p> <p>10. mblsmkexp_meta_annot_R1.csv</p> <p>Meta-analyzed european EWAS of maternal smoking exposure (hours per week).</p>
Evaluating Human Health Risks with Microbial Source Tracking and Quantitative Microbial Risk Assessment in Little Bay, Texas
<p>These results are the median human health risks associated with a range of recreational activities (i.e., swimming, kayaking, fishing, boating, jet skiing) in Little Bay, Texas. The health risks were estimated based on a quantiative microbial risk assessment (QMRA) that was performed using enterococci concentrations as well as host-associated molecular marker (i.e., human, canine, gull) concentrations measured previously in Little Bay. These human health risks represent the probability of a gastrointestinal illness for recreators.</p>
Dataset related to article "Acetaldehyde in polyethylene terephthalate (PET) bottledwater: assessment and mitigation of health risk for consumers"
<p><em>The file contains the raw data related to the manuscript: "Acetaldehyde in Polyethylene Terephthalate (PET) Bottled Water: Assessment and Mitigation of Health Risk for Consumers"</em></p> <p><strong>Abstract</strong>: This study was designed to investigate the levels of acetaldehyde residues in polyethylene terephthalate bottled water and its significance in terms of consumer health. We analyzed 104 samples collected throughout Italy, so as to be representative of the national market. Parameters such as CO<sub>2</sub> level, shelf life, weight of the empty bottle and distance from the production sites to the point of sale were also collected. Although the levels of acetaldehyde complied with the limits established by Italian legislation, they varied widely, with concentrations ranging from 0.41 to 76.2 µg/L. An assessment of safety for human health, using the margin of exposure approach, showed that the amount of acetaldehyde in bottled water is unlikely to be of any safety concern for human health. The acetaldehyde residues were mainly due to CO<sub>2</sub> levels which influence solubility of acetaldehyde in water. They are also related to the size of the bottle and the distance from the store, but not to the shelf life, at least for 40 days. The findings suggest some good practices for a better product from the point of view of public health, like polymer quality and limitation of transport distances.</p> <p><strong>Funding</strong>: This research was funded by Mineracqua.</p> <p> </p>
Health Risks Forecast of Regional Air Pollution on Allergic Rhinitis: High-Resolution City-Scale Simulations in Changchun, China
<p>Here presented the forcasted results of Potential Morbidity Risk Index (PMRI) for the personal patients with allerigc rhinitis and the public health administrations, and these results are supplied to the published paper of "Health Risks Forecast of Regional Air Pollution on Allergic Rhinitis: High-Resolution City-Scale Simulations in Changchun, China".</p>
Data from: A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial
Open the record for dataset details and reuse information.
Health AI Risk Taxonomy (HART)
Open the record for dataset details and reuse information.
Data reported in development and cross-validation of a veterans mental health risk factor screen
<p>Background. VA primary care patients are routinely screened for current symptoms of PTSD, depression, and alcohol disorders, but many who screen positive do not engage in care. In addition to stigma about mental disorders and a high value on autonomy, some veterans may not seek care because of uncertainty about whether they need treatment to recover. A screen for mental health risk could provide an alternative motivation for patients to engage in care.</p> <p>Results. Twelve items assessing dissociation, emotional lability, life stress, and moral injury correctly classified 86% of those who later had elevated PTSD and/or depression symptoms (sensitivity) and 75% of those whose later symptoms were not elevated (specificity). Performance was also very good for 110 veterans who identified as members of ethnic/racial minorities.</p> <p>Conclusions. Mental health status was prospectively predicted in VA primary care patients with high accuracy using a screen that is brief, easy to administer, score, and interpret, and fits well into VA's integrated primary care. When care is readily accessible, appealing to veterans, and not perceived as stigmatizing, information about mental health risk may result in higher rates of engagement than information about current mental disorder status.</p>
Figure 1 in Heavy metal (cadmium, lead, and chromium) contamination in farmed fish: a potential risk for consumers' health
Figure 1. Map of the study area.
Figure. Location of the Beyşehir and Eğirdir lakes in Türkiye. in Health risk assessments of heavy metal concentrations via consumption of an invasive species, Carassius gibelio, from two large freshwater lakes of Türkiye
Figure. Location of the Beyşehir and Eğirdir lakes in Türkiye.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.