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232 results for “healthcare workers”

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zenodo40/100

IMPLEMENTING AND EVALUATING A PAEDIATRIC EMERGENCY MANAGEMENT TRAINING PROGRAM FOR PRIMARY HEALTHCARE WORKERS IN ZARIA

<p>Nigeria continues to grapple with alarmingly high under-five mortality rates, with approximately 2,300 children dying daily due to preventable and treatable diseases such as pneumonia, malaria, and diarrheal illnesses. This crisis is particularly pronounced in rural areas, where childhood mortality rates are significantly higher than in urban centres. For many rural communities, primary healthcare (PHC) centres serve as the sole access point to medical services, making these centres critical to addressing this public health challenge. Despite their importance, PHC centres often face significant challenges, including inadequate infrastructure, limited access to essential medications, and a shortage of adequately trained health personnel.</p> <p>This study aimed to implement and evaluate a Paediatric Emergency Management Training Program for healthcare workers at PHC centres in Zaria, Kaduna State. The primary objective was to assess the effectiveness of the training in improving the competency of health workers in managing common paediatric emergencies, thereby enhancing the overall quality of care provided at these centres.</p> <p>A cross-sectional descriptive study was conducted involving 139 healthcare workers from selected PHC centres in Sabon Gari and Zaria Local Government Areas, utilizing a multi-stage random sampling technique. Data collection was performed using a pre-tested, semi-structured, self-administered questionnaire designed to evaluate the participants' baseline knowledge, followed by an assessment after the training intervention. The data were analysed using SPSS version 21, with chi-square tests employed to examine the associations between variables. Results were presented using tables and charts for clarity.</p> <p>The findings revealed a generally low baseline competency in managing common paediatric emergencies among the healthcare workers. Specifically, 66 (48.5%) of the respondents demonstrated very poor knowledge regarding the causes of common paediatric emergencies, 32 (23.5%) had poor knowledge, 34 (25.0%) had good knowledge, and only 4 (2.9%) of the respondents exhibited excellent knowledge. Similarly, knowledge regarding the treatment of these emergencies was also lacking, with 46.7% of respondents showing very poor understanding, 34.1% having poor knowledge, 16.3% demonstrating good knowledge, and only 3.0% showing excellent knowledge. A statistically significant relationship was observed between academic qualifications and knowledge levels in both causes (p = 0.004) and treatment (p = 0.000) of paediatric emergencies.</p> <p>The low baseline knowledge underscores the critical need for targeted training interventions. The study highlights the importance of establishing a sustained partnership between the Department of Paediatrics at Ahmadu Bello University Teaching Hospital and the Departments of Primary Health Care in Zaria and Sabon Gari Local Governments. Regular training workshops, held quarterly, are recommended to continuously equip PHC workers with the necessary skills to effectively manage paediatric emergencies, ultimately contributing to a reduction in childhood mortality rates in the region.</p>

opencc-by-4.0Nov 2024View details →
zenodo40/100

Quality of work organization, distress and absenteeism among healthcare workers

<p>Database of the study &quot;Quality of work organization, distress and absenteeism among healthcare workers&quot; to be published.</p>

opencc-by-4.0Sep 2022View details →
zenodo40/100

Changing birth places to care for healthcare workers, lessons from the pandemic: a scoping review.

<p><strong>Abstract</strong></p> <p><strong>Background:</strong> Together with women giving birth, healthcare professionals involved in perinatal care faced significant challenges due to Covid-19 restrictions. The birth environment has been affected, influencing the quality and nature of interactions between care providers, women, and their families as well as the quality of care provided to women.</p> <p><strong>Aim:</strong> To identify, categorize and reflect on the most relevant aspects of the experience of healthcare workers, especially obstetricians and gynecologists, involved in the peripartum period, after the first wave of the Covid-19 pandemic up till now.</p> <p><strong>Methods:</strong> A scoping review was conducted. After conducting a literature search using a variety of online data- bases, 22 articles were included, and the main/recurrent themes were identified.</p> <p><strong>Results: </strong>The following main themes were described: fear of the virus, changes in the way care is provided, increase in the workload, mental health, psychological distress, support strategies, university education, and perspectives of health managers.</p> <p><strong>Discussion:</strong> Standard maternity departments appeared not appropriate to face the pandemic. Psychological distress on perinatal healthcare workers&rsquo;, the majority of whom were women, led to the impairment of their mental health, affecting the quality of care provided to women.&nbsp; A key role was played by healthcare managers support in shaping how doctors can cope and recover, and in reducing the mental health impact.</p> <p><strong>Conclusion:</strong> It is very important to address some of the most relevant issues to acknowledge the role of healthcare workers and improve the health systems organization to face future pandemics.</p>

opencc-by-4.0Nov 2022View details →
ClinicalTrials.gov40/100

Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine

ClinicalTrials.gov study NCT04334148. IPD Sharing: YES. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →
zenodo36/100

Prevalence of psychopathological symptoms and their determinants in 4 healthcare workers categories during the second year of COVID-19 pandemic

<p>Dataset including data presented in the paper:&nbsp;<strong>Prevalence of psychopathological symptoms and their determinants in 4 healthcare workers categories during the second year of COVID-19 pandemic</strong></p>

opencc-by-4.0Jan 2022View details →
dryad36/100

Protective effect conferred by prior infection and vaccination on COVID-19 in a healthcare worker cohort in South India

<p><span>The emergence of newer variants with the immune escape potential raises concerns about breakthroughs and re-infections resulting in future waves of infection. We examined the protective effect of prior COVID-19 disease and vaccination on infection rates among a cohort of healthcare workers (HCW) in South India during the second wave driven mainly by the delta variant. </span><span>Symptomatic HCWs were routinely tested by RT-PCR as per institutional policy. Vaccination was offered to all HCWs in late January, and the details were documented. We set up a non-concurrent cohort to document infection rates and estimated protective efficacy of prior infection and vaccination between 16th Apr to 31st May 2021, using a Cox proportional hazards model with time-varying covariates adjusting for daily incidence.</span></p> <p><span>Between June 2020 and May 2021, 2735 (23.9%) of 11,405 HCWs were infected, with 1412, including 32 re-infections, reported during the second wave. 6863 HCWs received two doses of vaccine and 1905 one dose. The protective efficacy of prior infection against symptomatic infection was 86.0% (95% CI 76.7% - 91.6%). Vaccination combined with prior infection provided 91.1% (95% CI 84.1% - 94.9%) efficacy. In the absence of prior infection, vaccine efficacy against symptomatic infection during the second wave was 31.8% (95% CI 23.5% – 39.1%).</span></p> <p><span>Prior infection provided substantial protection against symptomatic re-infection and severe disease during a delta variant-driven second wave in a cohort of health care workers.</span></p>

opencc-zeroApr 2022View details →
dryad36/100

Data from: Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trial

<p>Morbidity and mortality attributable to COVID-19 is devastating global health systems and economies. Bacillus Calmette Guérin (BCG) vaccination has been in use for many decades to prevent severe forms of tuberculosis in children. Studies have also shown a combination of improved long-term innate or trained immunity (through epigenetic reprogramming of myeloid cells) and adaptive responses after BCG vaccination, which leads to non-specific protective effects in adults. Observational studies have shown that countries with routine BCG vaccination programs have significantly less reported cases and deaths of COVID-19, but such studies are prone to significant bias and need confirmation. To date, in the absence of direct evidence, WHO does not recommend BCG for the prevention of COVID-19. This project aims to investigate in a timely manner whether and why BCG-revaccination can reduce infection rate and/or disease severity in health care workers during the SARS-CoV-2 outbreak in South Africa. </p> <p>These objectives will be achieved with a blinded, randomised controlled trial of BCG revaccination versus placebo in exposed front-line staff in hospitals in Cape Town. Observations will include the rate of infection with COVID-19 as well as the occurrence of mild, moderate or severe ambulatory respiratory tract infections, hospitalisation, need for oxygen, mechanical ventilation or death. HIV-positive individuals will be excluded. Safety of the vaccines will be monitored. A secondary endpoint is the occurrence of latent or active tuberculosis. Initial sample size and follow-up duration is at least 500 workers and 52 weeks. Statistical analysis will be model-based and ongoing in real time with frequent interim analyses and optional increases of both sample size or observation time, based on the unforeseeable trajectory of the South African COVID-19 epidemic, available funds and recommendations of an independent data and safety monitoring board. The study will be supported by a novel 3D lung organoid model of SARS-CoV-2 infection system that can mimic the cascade of immunological events after SARS-CoV-2 infection to determine and analyse the contribution of cellular components to the impact of BCG revaccination in this study.</p> <p>Given the immediate threat of the SARS-CoV-2 epidemic the trial has been designed as a pragmatic study with highly feasible endpoints that can be continuously measured. This allows for the most rapid identification of a beneficial outcome that would lead to immediate dissemination of the results, vaccination of the control group and outreach to the health authorities to consider BCG vaccination for all qualifying health care workers.</p>

opencc-zeroJul 2024View details →
zenodo36/100

SARS-CoV-2 vaccine breakthrough infections by Omicron and Delta variants in healthcare workers

<p>An observational prospective cohort study was conducted in vaccinated employees with acute SARS-CoV-2 infection between October 2021 and February 2022. Serological and molecular testing was performed to determine SARS-CoV-2 viral load, lineage, antibody levels, and neutral-ising antibody titres. A total of 571 (9.7%) employees experienced SARS-CoV-2 breakthrough infections during the enrolment period, of which 81 were included. The majority (n=79, 97.5%) was symptomatic and most (n=75, 92.6%) showed Ct-values &lt; 30 in RT-PCR assays. Twenty-four (30%) remained PCR-positive for &gt; 15 days. Neutralizing antibody titres were strongest for the wildtype, intermediate for Delta and lowest for Omicron variants. Omicron infections occurred at higher anti-RBD-IgG serum levels (p= 0.00001) and showed a trend for higher viral loads (p=0.14, median Ct-difference 4.3, 95% CI [-2.5-10.5]). For both variants, viral loads were signifi-cantly higher in participants with lower anti-RBD-IgG serum levels (p=0.02).&nbsp;</p>

opencc-by-4.0Mar 2023View details →
ClinicalTrials.gov36/100

A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers

ClinicalTrials.gov study NCT04816708. IPD Sharing: NO. Countries: 1. Publications: 1.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov36/100

Mindful Hand Hygiene for Healthcare Workers

ClinicalTrials.gov study NCT05261282. IPD Sharing: YES. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov36/100

AWARENESS Trial (AWARENESS) of Storytelling Through Music in Healthcare Workers

ClinicalTrials.gov study NCT04775524. IPD Sharing: YES. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov36/100

Emails Promoting COVID-19 Vaccination Among Healthcare Workers

ClinicalTrials.gov study NCT04728594. IPD Sharing: YES. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov36/100

Cereset Research In Healthcare Workers During COVID-19

ClinicalTrials.gov study NCT04682197. IPD Sharing: NO. Countries: 1. Publications: 63.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov36/100

Exhaustion and Needs in Frontline COVID-19 Healthcare Workers: Cross-sectional Study in a Belgian Population

ClinicalTrials.gov study NCT04344145. IPD Sharing: UNDECIDED. Countries: 1. Publications: 17.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov36/100

Online Multi-component Psychological Intervention for Healthcare Workers During COVID-19 Pandemic

ClinicalTrials.gov study NCT04890665. IPD Sharing: YES. Countries: 1. Publications: 20.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov36/100

BCG Vaccination to Protect Healthcare Workers Against COVID-19

ClinicalTrials.gov study NCT04327206. IPD Sharing: YES. Countries: 5. Publications: 6.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov36/100

Bacterial Contamination of Healthcare Worker Uniforms

ClinicalTrials.gov study NCT01537835. IPD Sharing: Not stated. Countries: 1. Publications: 2.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov36/100

Vanderbilt Pertussis Exposure Study: PEP in Vaccinated Healthcare Workers Following Pertussis Exposure

ClinicalTrials.gov study NCT00469274. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov36/100

New Jersey Healthcare Essential Worker Outreach and Education Study - Testing Overlooked Occupations

ClinicalTrials.gov study NCT04766333. IPD Sharing: NO. Countries: 1. Publications: 4.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov36/100

HepB-CpG Series for Healthcare Workers Who Are Hepatitis B Vaccine Nonresponders

ClinicalTrials.gov study NCT04456504. IPD Sharing: NO. Countries: 1. Publications: 1.

closedIPD-NOFeb 2026View details →

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record