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4 results for “hematoma expansion”
Noncontrast CT-Based Deep Learning for Predicting Hematoma Expansion Risk in Patients with Spontaneous Intracerebral Hemorrhage
ClinicalTrials.gov study NCT06602115. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Hematoma expansion shift analysis to assess acute intracerebral hemorrhage treatments
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Association between Medial Intracranial Carotid Artery Calcifications and Hematoma Expansion in Deep Intracerebral Hemorrhage.
<p>Background: Medial intracranial carotid arteries calcifications (ICAC) are associated with impaired vascular physiology, increased arterial stiffness and pulse pressure. Their presence might therefore be associated with increased risk of intracerebral hemorrhage (ICH) expansion, according to the avalanche model. We explored the association between ICAC presence and pattern and hematoma expansion (HE).</p> <p>Methods: retrospective analysis of a monocentric, prospectively collected cohort of ICH patients admitted between June 2017 and October 2023. ICAC pattern was determined by Kockelkoren’s rating scale on admission CT and medial ICAC were defined with a > 6 points cutoff. HE was analyzed as a dichotomous (≥6 mL and/or ≥33%) and as a categorical (none/mild/moderate/severe) variable and its predictors were explored with logistic and ordinal regression respectively, accounting for baseline volume, onset-to-CT time and anticoagulation. All the analyses were stratified by ICH location (supratentorial deep vs lobar ICH).</p> <p>Results: A total of 201 patients were included (median age 78, 42% females, 59% deep ICH). Medial ICAC were significantly more common in deep ICH with HE compared to non-expanders (72% vs 49%, p=0.03) whereas there was no association between ICAC and HE in lobar ICH (53% vs 52%, p=0.85).This association between medial ICAC and HE in deep ICH remained significant in logistic (aOR 3.11, 95%CI [1.19-9.06], p=0.03) and ordinal regression (acOR 2.42, 95%CI [1.19-4.99], p=0.01).</p> <p>Interpretation: Ipsilateral medial ICAC are associated with higher odds of HE in deep ICH. Our findings are best interpreted as hypothesis generating, requiring prospective validation and further research to characterize the underlying biological mechanisms.</p>
Predictors of Early Hematoma Expansion in Patients With Acute Intracerebral Hemorrhage (Clinical and Laboratory Study)
ClinicalTrials.gov study NCT06490978. IPD Sharing: Not stated. Countries: 0. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.