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Dataset results
384 results for “hemoglobin”
Docking of GSH and BPG to the hemoglobin molecule in the oxy and deoxy state
<p>Oxy-Hb contains four bound GSH molecules inside the cavity, two of them at the β-β interface (sites 1 and 2) and two at the α-α chains interface (sites 3 and 4). In deoxy-Hb, two GSH molecules from the β-β subunits interface are released from the sites 1 and 2 allowing BPG to bind. Reoxygenation of Hbb is associated with release of BPG from its binding site and binding of two GSH molecules to the sites 1 and 2. The sites 3 and 4 remain occupied by GSH independent of the Hb conformation.</p>
Assessment of skin autofluorescence and its association with glycated hemoglobin, cardiovascular risk markers and concomitant chronic diseases in children with type 1 diabetes
<p>This is the dataset for the publication "Assessment of skin autofluorescence and its association with glycated hemoglobin, cardiovascular risk markers and concomitant chronic diseases in children with type 1 diabetes".</p>
Hemoglobin as oxygen-dependent glutathione buffer
<p>This dataset is associated with the pre-print "Hemoglobin as oxygen-dependent glutathione buffer" DOI 10.5281/zenodo.5817228 </p>
The efficacy of hemoglobin spray in wound management: a systematic review and network meta-analysis of comparative studies
<p>PRISMA flow</p>
VTR case studies datasets: myoglobin against hemoglobin, RBDs of SARS-CoV-1 vs. SARS-CoV-2, and glucose-tolerant vs. non-tolerant β-glucosidases
<p>Description of the four files:</p> <ol> <li><strong>contacts.xlsx</strong> <ul> <li>List of detected contacts for the three case studies</li> </ul> </li> <li><strong>pymol_files_case_study_1.zip</strong> <ul> <li>Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 1: comparison between contacts of myoglobin against hemoglobin</li> </ul> </li> <li><strong>pymol_files_case_study_2.zip</strong> <ul> <li>Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 2: comparison between contacts of RBDs of SARS-CoV-1 vs. SARS-CoV-2 both complexed with the cell receptor ACE2</li> </ul> </li> <li><strong>pymol_files_case_study_3.zip</strong> <ul> <li>Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 3: comparison between contacts of glucose-tolerant vs. non-tolerant β-glucosidases </li> </ul> </li> </ol>
Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes
The unusual pattern of expression of hemoglobin (Hb) and myoglobin (Mb) among Antarctic notothenioid fishes provides an exceptional model system for assessing the impact of these proteins on oxidative stress. We tested the hypothesis that the lack of oxygen-binding proteins may reduce oxidative stress. Levels and activity of pro-oxidants, small-molecule and enzymatic antioxidants, and levels of oxidized lipids and proteins in liver, oxidative skeletal muscle, and heart ventricle were quantified in five species of notothenioid fishes differing in the expression of Hb and Mb. Levels of ubiquitinated proteins and rates of protein degradation by the 20S proteasome were also quantified. Although levels of oxidized proteins and lipids, ubiquitinated proteins, and antioxidants are higher in red-blooded fishes than in Hb-less icefishes in some tissues, this pattern does not persist across all tissues. Expression of Mb is not associated with oxidative damage in heart ventricle, whereas the activity of citrate synthase and contents of heme are positively correlated with oxidative damage in most tissues. Despite some tissue differences in levels of protein carbonyls among species, rates of degradation by the 20S proteasome are not markedly different, suggesting either alternative pathways for eliminating oxidized proteins or redox tone varies among species. Together, our data indicate that the loss of Hb and Mb does not correspond with a clear pattern of either reduced oxidative defense or oxidative damage.
Computational modeling of hemoglobin saturation heterogeneity in capillary networks
<p>This repository contains the C++ code based on OpenFOAM used for simulating oxygen transport with moving red blood cells. The OpenFOAM cases used to generate all results in the research article "The heterogeneity of hemoglobin saturation in capillaries and its relation to red blood cell transit time" are included.</p> <p>The archive 'code-axisymmetric.tgz' contains the code for the simulations in axisymmetric domains. This code works with OpenFOAM 2.1.1.</p> <p>The archive 'code-parallel_capillaries.tgz' contains the code for the simulations with parallel capillaries. This code is based on OpenFOAM 2.3.0.</p> <p>The archive 'code-graph.tgz' contains the simulation code for the simulations in reconstructed capillary networks. The postprocessing and plotting script are also in this archive. This code is based on OpenFOAM 2.3.0.</p> <p>The archive 'code-flow_reconstruction.tgz' contains the code for the flow reconstruction algorithm.</p> <p>The remaining archives contain the OpenFOAM cases that were used to run the oxygen transport simulations reported in the research article "The Heterogeneity of Hemoglobin Saturation in Capillary Networks and its Relation to Red Blood Cell Transit Time".</p>
The efficacy of hemoglobin spray in wound management: a systematic review and network meta-analysis of comparative studies
<p>Dataset</p>
Acid blood gases including fetal hemoglobin from newborns, 2019-2023, General University Hospital in Prague
<p>This anonymized data is from the e-health database of the General University Hospital. It has blood gases that include the parameter of fetal hemoglobin percentage.</p> <p>The variables are as follows</p> <p>birthweight - birthweight</p> <p>EGA - gestational age in decimals</p> <p>day_of_life - postnatal day of life when the sample was taken</p> <p>blood_type - source of blood sample (a - arterial, c - capillary, v - venous)</p> <p>nr_of_preceding_trf - the amount of transfusions the patient has received preceding this blood sample</p> <p>hb - hemoglobin (g/l)</p> <p>F-hbf - fetal hemoglobin percentage</p> <p>pco2 - partial pressure of carbon dioxide (kPa)</p> <p>po2 - partial pressure of oxygen (kPa)</p> <p>so2 - oxygen saturation (ratio of oxyhemoglobin to total)</p> <p>pH - pH</p> <p>PO2 - partial pressure of oxygen (mmHg)</p> <p>estPaO2 - estimated partial pressure of oxygen at the given oxygen saturation according to the Severinghaus equation (mmHg)</p> <p>PaO2-extPO2 - difference between actual measured and estimated partial pressure of oxygen at the given oxygen saturation</p> <p>PCO2 - partial pressure of carbon dioxide (mmHg)</p>
fNIRS Hemoglobin Concentration Data
<p>Dataset taken from https://drive.google.com/drive/folders/0B1ZwONZKxJgTMUU0QnF6ZDE4ZVE?resourcekey=0-CrRWgI5JPNpSgk9FFsF7DQ</p> <p>Stored on Zenodo as backup for Stumpy Annotation Vectors</p>
The Relationship of Hemoglobin A1c and Diabetic Wound Healing
ClinicalTrials.gov study NCT01350102. IPD Sharing: NO. Countries: 1. Publications: 20.
Efficacy and Safety of Sotagliflozin in Young Adult Patients With Type 1 Diabetes Mellitus and Elevated Hemoglobin A1C
ClinicalTrials.gov study NCT02383940. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency
ClinicalTrials.gov study NCT02888171. IPD Sharing: NO. Countries: 1. Publications: 1.
A Randomized Clinical Trial on Hemoglobin Dose and Patient Matching
ClinicalTrials.gov study NCT01328262. IPD Sharing: NO. Countries: 1. Publications: 1.
STABIL Study: National Study With Mircera for Maintenance of Hemoglobin Level in Dialysis Patients
ClinicalTrials.gov study NCT00642850. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease
ClinicalTrials.gov study NCT00532883. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Utility of Postoperative Hemoglobin Testing
ClinicalTrials.gov study NCT04170764. IPD Sharing: Not stated. Countries: 1. Publications: 1.
CytoSorb Reduction of Free Hemoglobin During Cardiac Surgery
ClinicalTrials.gov study NCT02566525. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Hemoglobin-to-red Blood Cell Distribution Width Ratio and Hypothermia for Elderly Patient
ClinicalTrials.gov study NCT06790017. IPD Sharing: NO. Countries: 1. Publications: 2.
Non-Invasive Hemoglobin Monitoring in Patients With Hemorrhage
ClinicalTrials.gov study NCT01709786. IPD Sharing: NO. Countries: 1. Publications: 11.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.