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35 results for “heterotopic ossification”
Heterotopic Ossification Prophylaxis
ClinicalTrials.gov study NCT04867278. IPD Sharing: NO. Countries: 1. Publications: 5.
Prevention of Heterotopic Ossification With Arcoxia After Total Hip Replacement
ClinicalTrials.gov study NCT01022190. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Multi-center observational study on occurrence and related clinical factors of neurogenic heterotopic ossification in patients with disorders of consciousness
<p><strong>Aims</strong>: to assess occurrence and clinical correlates of neurogenic heterotopic ossifications (NHO) in patients with prolonged disorder of consciousness (DoC).<strong>Design</strong>: multi-center cross-sectional observational study.<strong>Setting</strong>: 23 intensive neurorehabilitation units.<strong>Subjects</strong>: 287 patients with prolonged disorder of consciousness (DoC; 150 in vegetative state, VS, and 128 in minimally conscious state, MCS) of different etiology (vascular = 125, traumatic = 83, anoxic = 56, others = 14).<strong>Main Measures</strong>: clinical evidence of NHO confirmed by standard radiological and/or sonographic evaluation; Coma Recovery Scale-Revised; Disability Rating Scale (DRS); Early Rehabilitation Barthel Index; presence of ventilator support, spasticity, bone fractures and paroxysmal sympathetic hyperactivity.<strong>Results</strong>: 31 patients (11.2%) presented NHO. Univariate analyses showed that NHO was associated with VS diagnosis, traumatic etiology, high DRS category and total score, and high occurrence of limb spasticity and bone fractures. A cluster-corrected binary logistic regression model (excluding spasticity available in a subset of patients) showed that only lower DRS total score and presence of bone fractures were independently associated with NHO.<strong>Conclusions</strong>: NHO are relatively frequent in patients with DoC, and are independently associated with functional disability, bone fractures and spasticity. These findings contribute to identifying patients with DoC prone to develop NHO and requiring special interventions to improve functional recovery.</p>
An Observational Pre-post Study to Observe if the Off Label Use of Anti-IL1 Therapies, Such as Anakinra or Canakinumab, Can Block ACVR1-induced Flare Activity and Heterotopic Ossification in FOP
ClinicalTrials.gov study NCT06724562. IPD Sharing: YES. Countries: 1. Publications: 2.
Elbow Heterotopic Ossifications Associated With Radial Head Prosthesis
ClinicalTrials.gov study NCT05547867. IPD Sharing: NO. Countries: 1. Publications: 18.
Heterotopic Ossification in Abdominal Incision and Pancreatic Cancer
ClinicalTrials.gov study NCT04049461. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Celecoxib for Primary Prophylaxis of Combat-Related Heterotopic Ossification
ClinicalTrials.gov study NCT01631669. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Continuous Passive Motion Versus Heterotopic Ossification
ClinicalTrials.gov study NCT05906056. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Engineered Osteoclasts as Living Treatment Materials for Heterotopic Ossification Therapy
<p>All data generated in this study are provided in the Supplementary materials and raw data. The data that support the findings of this study are available from the corresponding authors in reasonable request.</p>
Study of Pamidronate for the Prevention of Heterotopic Ossification
ClinicalTrials.gov study NCT00262392. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Differential expression profiles of circRNA in mice with traumatic heterotopic ossification
GEO Series GSE217301. Mus; Mus musculus. 8 samples. Type: Non-coding RNA profiling by array.
Transcriptome analysis of heterotopic ossification mesenchymal stromal cells
GEO Series GSE94683. Homo sapiens. 16 samples. Type: Expression profiling by array.
Palovarotene action against heterotopic ossification includes the inhibition of local participating activin-A expressing cell populations
GEO Series GSE233843. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
GEO Series GSE237512. Homo sapiens. 39 samples. Type: Expression profiling by high throughput sequencing.
Tenomodulin prevents trauma-induced heterotopic ossification in tendon
GEO Series GSE179454. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Elucidating the Mechanism of Radiation Therapy on Mesenchymal Cell Fate in Heterotopic Ossification
GEO Series GSE266978. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Activin A promotes the development of acquired heterotopic ossification and is an effective target for disease attenuation in mice
GEO Series GSE157679. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Role of myeloid cells in heterotopic ossification (HO) in a burn and incision-induced mouse model
GEO Series GSE126060. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
Gene expression microarray analysis of whole mouse hamstring muscles to identify genes promoting the devlopment of neurogenic heterotopic ossifications following spinal cord injury
GEO Series GSE165062. Mus musculus. 16 samples. Type: Expression profiling by array.
Radiation Therapy for Heterotopic Ossification Prophylaxis Acutely After Elbow Trauma
ClinicalTrials.gov study NCT00991887. IPD Sharing: NO. Countries: 0. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.