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12
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ShareScore release 0.9.0
Dataset results
12 results for “high risk setting”
Managing Type 1 and High Risk Type 2 Diabetes in the Hospital Setting: Glucose as a Vital Sign
ClinicalTrials.gov study NCT03068273. IPD Sharing: NO. Countries: 1. Publications: 1.
Real wOrld studY in the Adjuvant Setting for High Risk earLy Breast Cancer Patients
ClinicalTrials.gov study NCT07151911. IPD Sharing: NO. Countries: 1. Publications: 9.
High Risk Crack Use Settings and HIV in El Salvador
ClinicalTrials.gov study NCT01279421. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Standardized Perioperative Management of Patients Operated With Acute Abdominal Surgery in a High-risk Emergency Setting
ClinicalTrials.gov study NCT03549624. IPD Sharing: NO. Countries: 1. Publications: 3.
A Study to Evaluate Alzheimer's Disease Conversion Rate Differences Between High-risk Mild Cognitive Impairment (MCI) and Low-risk MCI in a Real World Setting
ClinicalTrials.gov study NCT03448445. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
ClinicalTrials.gov study NCT06151158. IPD Sharing: NO. Countries: 1. Publications: 2.
data set related to article Parent-Infant interaction during the first year of life in infants at high risk for cerebral palsy: a systematic review of the litarature
<pre>This record contains raw data related to article Parent-Infant interaction during the first year of life in infants at high risk for cerebral palsy: a systematic review of the litarature</pre>
Phase II Study of RAD001 in a Neoadjuvant Setting in Men With Intermediate or High Risk Prostate Cancer
ClinicalTrials.gov study NCT00657982. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)
ClinicalTrials.gov study NCT01045798. IPD Sharing: YES. Countries: 0. Publications: 0.
Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting
ClinicalTrials.gov study NCT05079113. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluating the Feasibility of High-volume, Low-risk Penicillin Allergy De-labelling to Maximise Efficiency in a Resource-limited Setting
ClinicalTrials.gov study NCT06532448. IPD Sharing: NO. Countries: 0. Publications: 0.
Data set from Pappone C, Mecarocci V, Manguso F, Ciconte G, Vicedomini G, Sturla F, Votta E, Mazza B, Pozzi P, Borrelli V, Anastasia L, Micaglio E, Locati E, Monasky MM, Lombardi M, Calovic Z, Santinelli V. New electromechanical substrate abnormalities in high-risk patients with Brugada syndrome. Heart Rhythm. 2020 Apr;17(4):637-645. doi: 10.1016/j.hrthm.2019.11.019. Epub 2019 Nov 19. PMID: 31756528.
<p>Data set from Pappone C, Mecarocci V, Manguso F, Ciconte G, Vicedomini G, Sturla F, Votta E, Mazza B, Pozzi P, Borrelli V, Anastasia L, Micaglio E, Locati E, Monasky MM, Lombardi M, Calovic Z, Santinelli V. New electromechanical substrate abnormalities in high-risk patients with Brugada syndrome. Heart Rhythm. 2020 Apr;17(4):637-645. doi: 10.1016/j.hrthm.2019.11.019. Epub 2019 Nov 19. PMID: 31756528.</p> <p> </p> <p>This is the abstract:</p> <p><strong>Background: </strong> The relationship between the typical electrocardiographic pattern and electromechanical abnormalities has never been systematically explored in Brugada syndrome (BrS).</p> <p><strong>Objectives: </strong> The aims of this study were to characterize the electromechanical substrate in patients with BrS and to evaluate the relationship between electrical and mechanical abnormalities.</p> <p><strong>Methods: </strong> We enrolled 50 consecutive high-risk patients with BrS (mean age 42 ± 7.2 years), with implantable cardioverter-defibrillator implantation for primary or secondary prevention of ventricular tachyarrhythmias (ventricular tachycardia/ventricular fibrillation [VT/VF]), undergoing substrate mapping and ablation. Patients underwent 3-dimensional (3D) echocardiography with 3D wall motion/deformation quantification and electroanatomic mapping before and after ajmaline administration (1 mg/kg in 5 minutes); 3D mechanical changes were compared with 50 age- and sex-matched controls. The effect of substrate ablation on electromechanical abnormalities was also assessed.</p> <p><strong>Results: </strong> In all patients, ajmaline administration induced Brugada type 1 pattern, with a significant increase in the electrical substrate (P < .001), particularly in patients with previous spontaneous VT/VF (P = .007). Induction of Brugada pattern was associated with lowering of right ventricular (RV) ejection fraction (P < .001) and worsening of 3D RV mechanical function (P < .001), particularly in the anterior free wall of the RV outflow tract, without changes in controls. RV electrical and mechanical abnormalities were highly correlated (r = 0.728, P < .001). By multivariate analysis, only the area of RV dysfunction was an independent predictor of spontaneous VT/VF (odds ratio 1.480; 95% confidence interval 1.159-1.889; P = .002). Substrate ablation abolished both BrS-electrocardiographic pattern and mechanical abnormalities, despite ajmaline rechallenge.</p> <p><strong>Conclusion: </strong> BrS is an electromechanical disease affecting the RV. The typical BrS pattern reflects an extensive RV arrhythmic substrate, driving consistent RV mechanical abnormalities. Substrate ablation abolished both Brugada pattern and mechanical abnormalities.</p> <p> </p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.