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13 results for “holocentric”
Data from: Sex-specific recombination landscape in a species with holocentric chromosomes
<p>Male and female meiosis typically exhibit significant differences in crossover locations along chromosomes. It has been suggested that higher recombination rates at chromosome centers in females counteract centromere-associated meiotic drivers, increasing their chances of segregating into the oocyte rather than to the non-viable polar bodies. Our research, employing the first sex-specific recombination map for an organism lacking defined centromeres revealed parallel recombination landscapes across the sexes, supporting the meiotic drive hypothesis.</p>
RAD-SEQ LINKAGE MAPPING AND PATTERNS OF SEGREGATION DISTORTION IN SEDGES: MEIOSIS AS A DRIVER OF KARYOTYPIC EVOLUTION IN ORGANISMS WITH HOLOCENTRIC CHROMOSOMES" in Journal of Evolutionary Biology
<p>This a data set from the paper RAD-SEQ LINKAGE MAPPING AND PATTERNS OF SEGREGATION DISTORTION IN SEDGES: MEIOSIS AS A DRIVER OF KARYOTYPIC EVOLUTION IN ORGANISMS WITH HOLOCENTRIC CHROMOSOMES" to be published in Journal of Evolutionary Biology</p>
Data from: Functional monocentricity with holocentric characteristics and chromosome-specific centromeres in a stick insect
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Data from: Chromosomes tell half of the story: the correlation between karyotype rearrangements and genetic diversity in sedges, a group with holocentric chromosomes
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Data from: The phylogenetic origins and evolutionary history of holocentric chromosomes
In eukaryotes, we can recognize two kinds of chromosomes, based on the location of the kinetochores. The majority of eukaryotes have monocentric chromosomes, in which kinetochoric activity is concentrated in a single locus. In several unrelated eukaryotic lineages, chromosomes are holocentric, having diffuse centromeric / kinetochoric activity along the length of the chromosome. Whether holocentric chromosomes are derived or ancestral is still under debate. This study uses the phylogenetic tree from Time Tree of Life project, comprising more than 50,000 sampled species, to reconstruct the evolution of holocentry. Asymmetrical two-state Markov (Mk2) models were compared with BiSSE models to assess sensitivity of our conclusions to possible effects of holocentry on lineage diversification rates. Our analyses based on Mk2 and BiSSE models inferred that the rate of transition from holocentric to monocentric chromosomes is two orders of magnitude higher than the reverse direction. The ancestral state of all eukaryotes is ambiguous depending on the model, inferred to be either monocentric (Mk2) or holocentric (BiSSE). Whatever the direction, the multiple transitions and high diversity of centromere organization across the tree of life are what we would expect if there are selective advantages to both chromosome types. Understanding those selective advantages is key to understanding how genetic information is organized and transmitted from one generation to the next, and why these major evolutionary transitions in centromere organization have occurred in the first place.
Figure 1-8 from: Suman V, Kaur H (2013) First report on C-banding, fluorochrome staining and NOR location in holocentric chromosomes of Elasmolomus (Aphanus) sordidus Fabricius, 1787 (Heteroptera, Rhyparochromidae). ZooKeys 319: 283-291. https://doi.org/10.3897/zookeys.319.4265
Figure 1-8 - C-banding (1, 2) 1, 2 Diplotene stages showing distribution of C-bands. Arrows showing heterochromatic chromosomes while arrowhead showing single euchromatic chromosome. Sequence-specific banding (3–6) 3 Diplotene stage with DAPI 4 Diplotene stage with localized CMA3 signals on one autosomal bivalent (shown by arrows) 5 Late diplotene stage with DAPI 6 Late diplotene stage with CMA3. Silver banding (7, 8) 7, 8 Diplotene stages showing location of NORs (shown by arrows) and nucleolar bodies (N). Bar=0.01 mm.
Data from: The phylogenetic origins and evolutionary history of holocentric chromosomes
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Unique territorial and sub-chromosomal organization revealed in the holocentric moth Bombyx mori [ChIP-seq]
GEO Series GSE228397. Bombyx mori. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Unique territorial and sub-chromosomal organization revealed in the holocentric moth Bombyx mori [Hi-C embryo]
GEO Series GSE228400. Bombyx mori. 3 samples. Type: Other.
Unique territorial and sub-chromosomal organization revealed in the holocentric moth Bombyx mori [Hi-C head]
GEO Series GSE228399. Bombyx mori. 1 samples. Type: Other.
Unique territorial and sub-chromosomal organization revealed in the holocentric moth Bombyx mori [RNA-seq]
GEO Series GSE228398. Bombyx mori. 3 samples. Type: Expression profiling by high throughput sequencing.
Unique territorial and sub-chromosomal organization revealed in the holocentric moth Bombyx mori
GEO Series GSE228401. Bombyx mori. 27 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
ChIP-seq of holocentric Chionographis japonica to determine the centromere distribution and genome organization
GEO Series GSE228407. Chionographis japonica; Secale cereale. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.