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347 results for “hypothermia”
The model output for the hypothermia case during the 2021 Ultramarathon
<p>The datasets are WRF model outputs for the hypothermia case during the 2021 Ultramarathon. The essential datasets are selected to support the study "Simulation of the effect of small-scale mountains on weather conditions during the May 2021 Ultramarathon in Gansu Province, China".</p>
Raw data of hypothermia and seizure intensity scores
Open the record for dataset details and reuse information.
Data from: Neuroprotection provided by hypothermia initiated with high transnasal flow with ambient air in a model of pediatric cardiac arrest
<p>Clinical trials of hypothermia after pediatric cardiac arrest have not seen robust improvement in functional outcome, possibly because of the long delay in achieving target temperature. Previous work in infant piglets showed that high nasal airflow, which induces evaporative cooling in the nasal mucosa, reduced regional brain temperature uniformly in half the time needed to reduce body temperature. The mouth is kept open to allow the high nasal airflow to easily exit. Here, we evaluated whether initiation of hypothermia with high transnasal airflow (32 L/min) provides neuroprotection without adverse effects in the setting of asphyxic cardiac arrest. Anesthetized, mechanically ventilated piglets (approximately 2-weeks-old) underwent sham-operated procedures (Group 1) or asphyxic cardiac arrest (Groups 2-6). The asphyxic insult consisted of reducing the inspired oxygen from 30% to 9.5-10% for 45 minutes (hypoxia period), then briefly increasing the inspired oxygen to 21% for 5 min (to improve the later success of cardiac resuscitation), and then completely stopping ventilation for 7 minutes. Cardiopulmonary resuscitation (CPR) commenced by re-establishing ventilation, performing chest compression, and injecting epinephrine as needed. The five cardiac arrest groups were further divided into those with normothermic recovery (38.5°C; Group 2), with mild hypothermia (34°C) initiated by surface cooling at 10 minutes (Group 3) or 120 minutes (Group 5) after resuscitation, or with mild hypothermia (34°C) initiated by transnasal cooling initiated at 10 minutes (Group 4) or 120 minutes (Group 6) after resuscitation. In the two transnasal cooling groups, the high nasal airflow continued for 2 hours and was then stopped; thereafter, surface cooling was used to maintain hypothermia. In all four groups with induced hypothermia, rectal temperature was sustained at the targeted temperature of 34°C with surface cooling until 20 hours after resuscitation, followed by 6 hours of gradual rewarming and cessation of fentanyl/70% nitrous oxide anesthesia.<strong> </strong>At four days of recovery, the piglets were euthanized and their brains were analyzed for the density of morphologically intact neurons in putamen, sensorimotor cortex, ventrolateral thalamus, and prefrontal cortex. The data sheet shows the density of viable neurons in these 4 brain regions for the 45 piglets that completed the study. The data sheet also shows the serial measurements of rectal temperature, mean arterial blood pressure, heart rate, and arterial blood measurements of the partial pressure of oxygen (PO2) and carbon dioxide (PCO2), oxyhemoglobin saturation, and pH obtained at baseline, during the period of hypoxia, at 4 minutes of ventilation with 21% O2, during the period of asphyxia, and during the first 24 hours of recovery. The piglets are assigned the same unique identifier number, labelled 1-45, for each set of measurements. Transnasal cooling initiated at 10 minutes after resuscitation was able to significantly rescue neurons in the highly vulnerable putamen without adverse effects.</p>
A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest
ClinicalTrials.gov study NCT01413399. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
ClinicalTrials.gov study NCT03111875. IPD Sharing: YES. Countries: 2. Publications: 2.
Safety and Efficacy of Hypothermia to Treat Neonatal Hypoxic-Ischemic Encephalopathy
ClinicalTrials.gov study NCT00890409. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial
ClinicalTrials.gov study NCT00880087. IPD Sharing: Not stated. Countries: 3. Publications: 10.
Mild Hypothermia and Acute Kidney Injury in Liver Transplantation
ClinicalTrials.gov study NCT03534141. IPD Sharing: NO. Countries: 1. Publications: 6.
Impact of Speed Of Rewarming After CaRdiac Arrest and ThErapeutic Hypothermia
ClinicalTrials.gov study NCT02555254. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia
ClinicalTrials.gov study NCT00934700. IPD Sharing: NO. Countries: 1. Publications: 2.
Preemie Hypothermia for Neonatal Encephalopathy
ClinicalTrials.gov study NCT01793129. IPD Sharing: YES. Countries: 1. Publications: 1.
Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO)
ClinicalTrials.gov study NCT01913340. IPD Sharing: Not stated. Countries: 1. Publications: 7.
The Effect of Perioperative Heated Sock Use in Preventing Hypothermia During Total Hip Prosthesis Surgery
ClinicalTrials.gov study NCT06541054. IPD Sharing: YES. Countries: 1. Publications: 1.
Optimising Newborn Nutrition During Therapeutic Hypothermia.
ClinicalTrials.gov study NCT03278847. IPD Sharing: YES. Countries: 1. Publications: 4.
Kangaroo Mother Care to Prevent Hypothermia in Term Infants
ClinicalTrials.gov study NCT02189759. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Anti-inflammatory Effect of Therapeutic Hypothermia in Out-hospital Cardiac Arrest Patients With Cardiogenic Shock
ClinicalTrials.gov study NCT02633358. IPD Sharing: NO. Countries: 1. Publications: 8.
The Effect of Perioperative Heated Sock Application on Hypothermia and Vital Signs in Bladder Tumor Surgery
ClinicalTrials.gov study NCT06988696. IPD Sharing: YES. Countries: 1. Publications: 1.
Influence of Mild Hypothermia on Reversal of Rocuronium With Sugammadex
ClinicalTrials.gov study NCT01965067. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Hypothermia Upon Outcomes After Acute Traumatic Brain Injury
ClinicalTrials.gov study NCT00178711. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Safety of Clonidine in Infants With Hypoxic Ischemic Encephalopathy During Therapeutic Hypothermia
ClinicalTrials.gov study NCT01862250. IPD Sharing: NO. Countries: 1. Publications: 5.
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International Brain Laboratory public data
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OpenNeuro
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