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Dataset results
155 results for “iPSC-derived neurons”
Molecular and functional variation in iPSC-derived sensory neurons
<p>These files contain summary statistics for gene expression QTLs and splicing QTLs from an RNA-sequencing study of iPSC-derived sensory neurons from 97 individuals.</p>
Somatic mutations alter the differentiation outcomes of iPSC-derived neurons (Metadata and AnnData/H5AD files)
<p><strong>Data S1:</strong> Metadata information for the 828,937 processed cells from the DN dataset: donor identity, cell type annotation, pool identifier, 10x sample, time point and replicate information. Related to STAR Methods: Reanalysis of pooled single-cell data (DA).</p> <p><strong>Data S2-S4:</strong> AnnData/H5AD files containing the single-cell gene expression matrices and the metadata for day 11, day 30 and day 52, respectively. The gene expression is normalised and log-transformed, but not scaled. md5 files are also included. Related to STAR Methods: DE analysis between failed and successful lines.</p> <p>#File names:</p> <p><strong>File-Data S1: </strong>suppData1.RDS</p> <p><strong>File-Data S2: </strong>allpools.scanpy.D11.wMetaClustUmapGraph.exprLogNormNotScaled_notKO.h5ad</p> <p><strong>File-Data S3: </strong>allpools.scanpy.D30.wMetaClustUmapGraph.exprLogNormNotScaled_notKO.h5ad</p> <p><strong>File-Data S4: </strong>allpools.scanpy.D52.wMetaClustUmapGraph.exprLogNormNotScaled_notKO.h5ad</p>
Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial
ClinicalTrials.gov study NCT06976229. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Autologous iPSC-Derived Dopamine Neuron Transplantation for Parkinson's Disease
ClinicalTrials.gov study NCT06422208. IPD Sharing: NO. Countries: 1. Publications: 12.
Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons
<p>The tabular dataset for all graphs in Rafiq et al 2024 can be found in the ASAP data repository</p>
Efficacy of iPSC-Derived Motor Neuron Cells (XS228) in Subacute Spinal Cord Injury: A Phase II Randomized Controlled Trial
ClinicalTrials.gov study NCT06974968. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Human Huntington’s Disease iPSC-derived cortical neurons display altered transcriptomics, morphology and electrophysiological maturation
GEO Series GSE109534. Homo sapiens. 42 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder
GEO Series GSE142670. Homo sapiens. 52 samples. Type: Expression profiling by high throughput sequencing.
A de novo Missense Mutation in PPP2R5D Alters Dopamine Pathways and Morphology of iPSC-derived Midbrain Neurons
GEO Series GSE238213. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons
GEO Series GSE86464. Homo sapiens; Mus musculus. 124 samples. Type: Expression profiling by array; Expression profiling by high throughput sequencing; Other; Non-coding RNA profiling by high throughput sequencing.
DPYSL2/CRMP2 isoform B knockout in human iPSC-derived glutamatergic neurons confirms its role in mTOR signaling and neurodevelopmental disorders
GEO Series GSE268103. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
GEO Series GSE25542. Homo sapiens. 59 samples. Type: Expression profiling by array.
Genome-wide transcriptome analysis of human iPSC-derived healthy control vs schizophrenia developmental glutamatergic neurons.
GEO Series GSE184102. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons [hnRNPA2B1_small_rnaseq]
GEO Series GSE86227. Homo sapiens; Mus musculus. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
H3K4me3 ChIP-Seq profiles of control and huntington's disease iPSC-derived medium spiny neuron-like cells
GEO Series GSE144493. Homo sapiens. 17 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program
GEO Series GSE88773. Mus musculus; Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
scRNAseq in human iPSC-derived motor neurons(hiPSC-MNs).
GEO Series GSE267791. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Genome wide analysis of SAHA (vorinostat) treatment in human iPSC-derived neurons from Tau A152T patients and controls
GEO Series GSE115205. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide analysis of iPSC-derived neurons with EGFP or TERT transduction
GEO Series GSE163525. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death.
GEO Series GSE207986. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.