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ShareScore release 0.9.0
Dataset results
18 results for “immunome”
Dataset: Immunome, Inc. (IMNM) Stock Performance
This dataset provides historical stock market performance data for specific companies. It enables users to analyze and understand the past trends and fluctuations in stock prices over time. This information can be utilized for various purposes such as investment analysis, financial research, and market trend forecasting.
Data from: Immunomics of the koala (Phascolarctos cinereus )
The study of the koala transcriptome has the potential to advance our understanding of its immunome—immunological reaction of a given host to foreign antigens—and to help combat infectious diseases (e.g., chlamydiosis) that impede ongoing conservation efforts. We used Illumina sequencing of cDNA to characterize genes expressed in two different koala tissues of immunological importance, blood and spleen. We generated nearly 600 million raw sequence reads, and about 285 million of these were subsequently assembled and condensed into ~70,000 subcomponents that represent putative transcripts. We annotated ~16 % of these subcomponents and identified those related to infection and the immune response, including Toll-like receptors (TLRs), RIG-I-like receptors (RLRs), major histocompatibility complex (MHC) genes, and koala retrovirus (KoRV). Using phylogenetic analyses, we identified 29 koala genes in these target categories and report their concordance with currently accepted gene groups. By mapping multiple sequencing reads to transcripts, we identified 56 putative SNPs in genes of interest. The distribution of these SNPs indicates that MHC genes (34 SNPs) are more diverse than KoRV (12 SNPs), TLRs (8 SNPs), or RLRs (2 SNPs). Our sequence data also indicate that KoRV sequences are highly expressed in the transcriptome. Our efforts have produced full-length sequences for potentially important immune genes in koala, which should serve as targets for future investigations that aim to conserve koala populations.
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset
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Data from: Immunomics of the koala (Phascolarctos cinereus )
Open the record for dataset details and reuse information.
Data from: Profiling the immunome of little brown myotis provides a yardstick for measuring the genetic response to white-nose syndrome
White-nose syndrome (WNS) has devastated populations of hibernating bats in eastern North America, leading to emergency conservation listings for several species including the previously ubiquitous little brown myotis (Myotis lucifugus). However, some bat populations near the epicenter of the white-nose syndrome panzootic appear to be stabilizing after initial precipitous declines, which could reflect a selective immunogenetic sweep. To investigate the hypothesis that WNS exerts significant selection on the immunome of affected bat populations, we developed a novel, high-throughput sequence capture assay targeting 138 adaptive, intrinsic, and innate immunity genes of putative adaptive significance, as well as their respective regulatory regions (~370-kbp of genomic sequence/individual). We used the assay to explore baseline immunogenetic variation in M. lucifugus and to investigate whether particular immune genes/variants are associated with WNS susceptibility. We also used our assay to detect 1,038 putatively neutral single-nucleotide polymorphisms and characterize contemporary population structure, providing context for the identification of local immunogenetic adaptation. Sequence capture provided a cost-effective, 'all-in-one' assay to test for neutral genetic and immunogenetic structure and revealed fine-scale, baseline immunogenetic differentiation between sampling sites < 600 kilometers apart. We identified functional immunogenetic variants in M. lucifugus associated with WNS susceptibility. This study lays the foundations for future investigations of range-wide immunogenetic adaptation to white-nose syndrome in M. lucifugus, and provides a blueprint for studies of evolutionary rescue in other host-pathogen systems.
Immunomics datasets: to identify potential candidates for chimeric vaccine design to cervix papilloma
<p>Immunomics datasets: to identify potential candidates for chimeric vaccine design to cervix papilloma</p>
Metabolic and Immunomic Differential Analysis of Primary Central Nervous System Diffuse Large B-Cell Lymphoma
ClinicalTrials.gov study NCT07188077. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Data from: Profiling the immunome of little brown myotis provides a yardstick for measuring the genetic response to white-nose syndrome
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RNA-seq tumor immunome analysis of murine breast cancer model EMT6-hHER2 responsive to novel antibody drug conjugate T-PNU
GEO Series GSE120888. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
HBV Immunomics 10X and Smart-seq2 integrated data
<p>Here, we established a single-cell RNA-sequencing (scRNA-seq) dataset of HBV immune responses in patients to contribute to a better understanding of the dysregulated immune response in CHB. We collected blood samples of a well-defined cohort of CHB and healthy controls including a subset of matched blood and liver samples. scRNA-seq data of 55,825 total immune cells as well as 131,367 sorted HBV-specific, non-naive and PD1+ T cells was generated using the 10X Genomics platform (186,123 cells) and the full-length Smart-seq2 protocol (1,069 cells). This unique scRNA-seq dataset serves as a resource describing T cell responses in patients and offers the opportunity to explore transcriptional changes underlying HBV-related immune cell dysfunction in blood and liver tissue and to identify new targets or biomarkers for HBV-related immune exhaustion.</p> <p><strong>This dataset includes the 10X and Smart-seq2 integrated data.</strong></p>
HBV Immunomics 10X data
<p>Here, we established a single-cell RNA-sequencing (scRNA-seq) dataset of HBV immune responses in patients to contribute to a better understanding of the dysregulated immune response in CHB. We collected blood samples of a well-defined cohort of CHB and healthy controls including a subset of matched blood and liver samples. scRNA-seq data of 55,825 total immune cells as well as 131,367 sorted HBV-specific, non-naive and PD1+ T cells was generated using the 10X Genomics platform (186,123 cells) and the full-length Smart-seq2 protocol (1,069 cells). This unique scRNA-seq dataset serves as a resource describing T cell responses in patients and offers the opportunity to explore transcriptional changes underlying HBV-related immune cell dysfunction in blood and liver tissue and to identify new targets or biomarkers for HBV-related immune exhaustion.</p> <p>This dataset incluces the 10X Genomics data only.</p> <p> </p>
Human Immunome Program
ClinicalTrials.gov study NCT03118687. IPD Sharing: YES. Countries: 1. Publications: 0.
Minimally INvasive Colon Cancer Surgery Through IMmunomics and Optical Mapping of the Sentinel Lymph Node.
ClinicalTrials.gov study NCT03779009. IPD Sharing: NO. Countries: 1. Publications: 0.
Immunome Project Consortium for Autoinflammatory Disorders
ClinicalTrials.gov study NCT03919110. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence in Glioblastoma
ClinicalTrials.gov study NCT05941234. IPD Sharing: NO. Countries: 1. Publications: 0.
Effects of Systemically Administered Hydrocortisone on the Human Immunome
GEO Series GSE67255. Homo sapiens. 108 samples. Type: Expression profiling by array.
The Immunome in Two Inherited Forms of Pulmonary Fibrosis
GEO Series GSE107797. Homo sapiens. 21 samples. Type: Expression profiling by array.
HBV Immunomics Smart-seq2 data
<p>Here, we established a single-cell RNA-sequencing (scRNA-seq) dataset of HBV immune responses in patients to contribute to a better understanding of the dysregulated immune response in CHB. We collected blood samples of a well-defined cohort of CHB and healthy controls including a subset of matched blood and liver samples. scRNA-seq data of 55,825 total immune cells as well as 131,367 sorted HBV-specific, non-naive and PD1+ T cells was generated using the 10X Genomics platform (186,123 cells) and the full-length Smart-seq2 protocol (1,069 cells). This unique scRNA-seq dataset serves as a resource describing T cell responses in patients and offers the opportunity to explore transcriptional changes underlying HBV-related immune cell dysfunction in blood and liver tissue and to identify new targets or biomarkers for HBV-related immune exhaustion.</p> <p><strong>This dataset includes the Smart-seq2 data only.</strong></p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.