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ShareScore release 0.9.0
Dataset results
7 results for “infection probability”
Data from: Individual genetic diversity and probability of infection by avian malaria parasites in blue tits (Cyanistes caeruleus)
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Data from: The stochastic dynamics of early epidemics: probability of establishment, initial growth rate, and infection cluster size at first detection
<p>Emerging epidemics and local infection clusters are initially prone to stochastic effects that can substantially impact the epidemic trajectory. While numerous studies are devoted to the deterministic regime of an established epidemic, mathematical descriptions of the initial phase of epidemic growth are comparatively rarer. Here, we review existing mathematical results on the epidemic size over time, and derive new results to elucidate the early dynamics of an infection cluster started by a single infected individual. We show that the initial growth of epidemics that eventually take off is accelerated by stochasticity. These results are critical to improve early cluster detection and control. As an application, we compute the distribution of the first detection time of an infected individual in an infection cluster depending on the testing effort, and estimate that the SARS-CoV-2 variant of concern Alpha detected in September 2020 first appeared in the United Kingdom early August 2020. We also compute a minimal testing frequency to detect clusters before they exceed a given threshold size. These results improve our theoretical understanding of early epidemics and will be useful for the study and control of local infectious disease clusters.</p>
Data from: The stochastic dynamics of early epidemics: probability of establishment, initial growth rate, and infection cluster size at first detection
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The probability of being infected with haemosporidian parasites increases with host age
<p><span><span><span><span><span><span><span><span><span><span><span>In vertebrates, disease susceptibility often varies with age. Older individuals may be more susceptible than younger individuals due to senescent declines in immune function. Alternatively, disease susceptibility may decrease with age if older individuals are more likely to have had prior exposures to parasites and acquired adaptive immune responses that allowed them to resist future infections. Disease susceptibility can also vary with reproductive state, and reproductive hormones have been shown to increase infection susceptibility. Here we investigated how age and experimentally elevated levels of the reproductive hormone testosterone affected haemosporidian infections in free-living adult male dark-eyed juncos (<i>Junco hyemalis</i>). Samples were collected before and at least one year after experimental treatment with either a testosterone implant or empty control implant. The probability of being infected with haemosporidians in the <i>Plasmodium/Haemoproteus </i>group increased with host age but was unaffected by experimental testosterone elevation. Our longitudinal sampling design allowed us to determine that the increase in infections with host age was driven by variation within individuals, such that an individual's probability of being infected increased with age. This suggests that haemosporidian susceptibility increases with host age, and/or that haemosporidian-infected juncos sustain long-term chronic infections that are rarely completely cleared, and that the probability of being infected is higher in older juncos because they have experienced higher cumulative exposure risk.</span></span></span></span></span></span></span></span></span></span></span></p>
The probability of being infected with haemosporidian parasites increases with host age
Open the record for dataset details and reuse information.
Caspofungin Based Combined Anti-fungal Therapy for Proven or Probable Invasive Fungal Infection
ClinicalTrials.gov study NCT01501708. IPD Sharing: NO. Countries: 1. Publications: 0.
Probability of Target Attainment With Standard Intermittent Bolus Administration of Cefazolin in Patients With Complicated Infections Caused by Staphylococcus Aureus
ClinicalTrials.gov study NCT04503252. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.