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ShareScore release 0.9.0
Dataset results
169 results for “inflammatory biomarkers”
Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease
ClinicalTrials.gov study NCT04514510. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Resveratrol Effects on Inflammatory Biomarkers and Cardiometabolic Parameters.
ClinicalTrials.gov study NCT07395921. IPD Sharing: NO. Countries: 1. Publications: 0.
Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal Conditions
ClinicalTrials.gov study NCT03912428. IPD Sharing: YES. Countries: 1. Publications: 7.
Data from: Maternal pre-pregnancy weight status modifies the influence of PUFAs and inflammatory biomarkers in breastmilk on infant growth
Background: Human breastmilk contains pro- and anti-inflammatory compounds and hormones that can influence infant growth. However, little is known about the specific interrelationships between these compounds and whether their effects on infant growth may be influenced by pre-pregnancy weight status. Objective: The purpose of this novel, prospective cohort study was to assess the interrelationships between pro-inflammatory cytokines (TNF-α, IL-6), hormones (insulin, leptin) and PUFAs (n-6, n-3) in blood and breastmilk in early postpartum between women with normal BMI (Group 1, n=18; 18.5
Data from: The interest of inflammatory biomarkers in the diagnostic approach
<p><span>Background</span><span>: </span><span>The role of inflammatory biomarkers in the etiological orientation is increasingly under study, and their potential significance is recognized. </span></p> <p><span>Methods:</span><span> Procalcitonin (PCT), neutrophil-lymphocyte ratio (NLR), C-reactive-protein (CRP), fibrinogen, ferritinaemia and lactate were measured on admission in all patients. The optimal cut-off values for the sensitivities and specificities to the infectious diseases were determined using the receiver operating curve(ROC) analysis and Youden's index. The diagnostic accuracy of biomarkers and their combinations for predicting infectious etiologies was calculated by area under the curve(AUC).</span></p> <p><span>Results:</span> <span>A total of 164 patients were included in the study.</span><span> The mean age was 50.7 ± 18 years [18 – 92 years]. Fifty-three patients (32.3%) were over 65 years old. Patients were split into four groups: 53 patients (32.3%) with infectious diseases of which 45 patients (84.9%) presented bacterial infections, 62 patients (37.8%) with inflammatory diseases, 14 patients (8.5%) with neoplasms and 35 patients (21.3%) with other diagnosis.</span><span> The high mean levels of Leukocytes (12047 cells/mm3, Neutrophils (9015 cells/mm<sup>3</sup>), Neutrophils to lymphocytes ratio (NLR) (9.7), C reactive protein (CRP) (152.5 mg/L), Procalcitonin (PCT)(3.28 ng/ml)and fibrinogen (5.37g/L) were </span><span>associated to infectious etiologies with statistically significant difference</span><span>s. Thus, we identified cut-offs of NLR(6.1), CRP (</span><span>123 mg/L),</span><span>PCT(0</span><span>.24 ng/mL)</span><span> and fibrinogen (4.9 g/L) to discriminate infectious etiologies in our population. </span><span>For diagnosing infectious diseases, the CRP showed higher AUC( Area under the curve) </span><span>(Sp: 89.7%, Se: 64.3%, AUC=0.9, CI: 0.83-0.96, p<10<sup>-3</sup>) t</span><span>han PCT (Sp: 86.1%,Se: 62.3%, AUC=0,87, CI:0.80-0.93, p<10-3), NLR (</span><span>Sp: 87.1%, Se: 61%, AUC=0.81, CI: 0.731- 0.902, p <10<sup>-3</sup></span><span>)</span><span> and Fibrinogen (Sp: 84.7%, Se:68.3%, AUC=0.77, CI: 0.65 – 0.98, p<10<sup>-3</sup>).</span><span>The combination of CRP and NLR levels improved the diagnostic accuracy (AUC 0.93, 95% CI 0.84–0.96; p< 10<sup>-3</sup>) for distinguishing between infectious and non-infectious diseases.</span></p> <p><span>Conclusions:</span> <span>Our study is characterized by the variety of included disease categories. It</span><span> showed the usefulness of inflammatory biomarkers, particularly the NLR and its combination with CRP, which are low cost and easy to assess, in promoting the diagnostic accuracy to distinguish infections among inflammatory, neoplasia and other diagnoses.</span></p>
Inflammatory and metabolic biomarker assessment in a randomized presurgical trial of curcumin and anthocyanin supplements in patients with colorectal adenomas
<p>Supplementary Figures of the manuscript entitled: Inflammatory and metabolic biomarker assessment in a randomized presurgical trial of curcumin and anthocyanin supplements in patients with colorectal adenomas.</p> <p>Supplementary Figure S1. Univariate analysis of IL-10 changes by BMI</p> <p>Supplementary Figure S2. Univariate analysis of leptin changes by dietary anthocyanin intake</p> <p>Supplementary Figure S3. Mixed models analysis of post-intervention IGFBP-3 by colorectal cancer family history</p> <p>Supplementary Figure S4. Mixed models analysis of adiponectin by treatment arm</p>
The Comparison Between the Biomarkers in Inflammatory Bowel Disease Patients and General Control Group
ClinicalTrials.gov study NCT03778918. IPD Sharing: NO. Countries: 1. Publications: 3.
The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in Migraine
ClinicalTrials.gov study NCT07292506. IPD Sharing: NO. Countries: 1. Publications: 3.
Investigation of the Effects of Curcumin and Resveratrol Supplements Added to the Mediterranean Diet on Disease Severity and Inflammatory Biomarkers in Patients With Ulcerative Colitis
ClinicalTrials.gov study NCT05761327. IPD Sharing: NO. Countries: 1. Publications: 12.
New Biomarkers in the Intracystic Liquid of Inflammatory and Non-inflammatory Pancreatic Cysts
ClinicalTrials.gov study NCT05568433. IPD Sharing: NO. Countries: 1. Publications: 10.
Association Between Inflammatory Biomarkers in CVD Patients on Empagliflozin.
ClinicalTrials.gov study NCT05911724. IPD Sharing: NO. Countries: 1. Publications: 6.
Effects of Vitamin D and Calcium Supplementation on Inflammatory Biomarkers and Adypocytokines in Diabetic Patients
ClinicalTrials.gov study NCT01662193. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Autoimmune and Inflammatory Response Biomarkers in Fabry Disease
ClinicalTrials.gov study NCT06007768. IPD Sharing: YES. Countries: 1. Publications: 11.
Biomarkers in Inflammatory Rheumatic Diseases Diagnosis
ClinicalTrials.gov study NCT06778343. IPD Sharing: NO. Countries: 1. Publications: 7.
Inflammatory Mediators as Potential Non-Invasive Biomarkers in Subjects With Eosinophilic Esophagitis
ClinicalTrials.gov study NCT03822325. IPD Sharing: UNDECIDED. Countries: 1. Publications: 12.
Evaluation of Systemic Inflammatory Index and Biomarkers in Relation to Inferior Alveolar Nerve Block Success and Postoperative Pain
ClinicalTrials.gov study NCT07163065. IPD Sharing: NO. Countries: 1. Publications: 2.
Inflammatory Biomarkers to Diagnose and Monitor Diabetic Foot Osteomyelitis
ClinicalTrials.gov study NCT04025853. IPD Sharing: NO. Countries: 1. Publications: 4.
Inflammatory Biomarkers and Brain Metabolites, a Study Based on Magnetic Resonance Spectroscopy
ClinicalTrials.gov study NCT03052855. IPD Sharing: NO. Countries: 1. Publications: 1.
Oral DLBS1033 as Adjunctive Therapy in Acute Ischemic Stroke: Impact on Inflammatory Biomarkers and Outcomes
ClinicalTrials.gov study NCT07121569. IPD Sharing: YES. Countries: 1. Publications: 2.
Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers
ClinicalTrials.gov study NCT01448291. IPD Sharing: Not stated. Countries: 1. Publications: 5.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.