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31
datasets available to search
ShareScore release 0.9.0
Dataset results
31 results for “interaction modification”
qPCR analysis: Arabidopsis AGO1 N-terminal extension acts as an essential hub for PRMT5 interaction and post-translational modifications
<p>Arabidopsis AGO1 N-terminal extension acts as an essential hub for PRMT5 interaction and post-translational modifications' qPCR data following the MIQE guidelines.</p>
Time dependent interaction modification generated from plant-soil feedback
<p>Pairwise interactions between species can be modified by other community members, leading to emergent dynamics contingent on community composition. Despite the prevalence of such higher-order interactions, little is known about how they are linked to the timing and order of species' arrival. We generate population dynamics from a mechanistic plant-soil feedback model, then apply a general theoretical framework to show that the modification of a pairwise interaction by a third plant depends on its germination phenology. These time-dependent interaction modifications emerge from concurrent changes in plant and microbe populations and are strengthened by higher overlap between plants' associated microbiomes. The interaction between this overlap and the specificity of microbiomes further determines plant coexistence. Our framework is widely applicable to mechanisms in other systems from which similar time-dependent interaction modifications can emerge, highlighting the need to integrate temporal shifts of species interactions to predict the emergent dynamics of natural communities.</p>
Time dependent interaction modification generated from plant-soil feedback
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Data from: Linking microenvironment modification to species interactions and demography in an alpine plant community
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Data from: The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications
<p></p><p>Microtubules are cytoskeletal structures involved in stability, transport and organization in the cell. The building blocks, the α- and β-tubulin heterodimers, form protofilaments that associate laterally into the hollow microtubule. Microtubule also exists as highly stable doublet microtubules in the cilia where stability is needed for ciliary beating and function. The doublet microtubule maintains its stability through interactions at its inner and outer junctions where its A- and B-tubules meet. Here, using cryo-electron microscopy, bioinformatics and mass spectrometry of the doublets of Chlamydomonas reinhardtii and Tetrahymena thermophila, we identified two new inner junction proteins, FAP276 and FAP106, and an inner junction-associated protein, FAP126, thus presenting the complete answer to the inner junction identity and localization. Our structural study of the doublets shows that the inner junction serves as an interaction hub that involves tubulin post-translational modifications. These interactions contribute to the stability of the doublet and hence, normal ciliary motility.</p><p></p>
Data from: The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications
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Dynamic regulation of histone modifications and long-range chromosomal interactions during post-mitotic transcriptional reactivation
GEO Series GSE141139. Homo sapiens. 114 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Dynamic regulation of histone modifications and long-range chromosomal interactions during post-mitotic transcriptional reactivation [ChIP-seq]
GEO Series GSE141081. Homo sapiens. 60 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Inseparable RNA binding and chromatin modification activities of a nucleosome-interacting surface in EZH2
GEO Series GSE199543. Homo sapiens. 77 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Dynamic regulation of histone modifications and long-range chromosomal interactions during post-mitotic transcriptional reactivation [EU-RNA-seq]
GEO Series GSE141137. Homo sapiens. 38 samples. Type: Expression profiling by high throughput sequencing.
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression [ChIP-Seq]
GEO Series GSE122757. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression [ATAC-Seq]
GEO Series GSE122756. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Glutamine 5 serotonylation on histone H3 is a permissive modification that functions combinatorialy with H3K4me3 to potentiate TFIID interactions
GEO Series GSE106495. Mus musculus; Homo sapiens; Rattus norvegicus. 87 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Inseparable RNA binding and chromatin modification activities of a nucleosome-interacting surface in EZH2
GEO Series GSE239447. Homo sapiens. 90 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Data from: Modification of Escherichia coli–bacteriophage interactions by surfactants and antibiotics in vitro
Although experiments indicate that the abiotic environment plays an important role in bacterial interactions with their parasitic viruses (bacteriophages or phages), it is not yet clear how exposure to compounds present in nature alters the impact of phages on bacterial growth and evolution. To address this question, we exposed Escherichia coli K12 MG1655, in combination with three lytic phages, to various substances that natural and clinical microbial populations are likely to encounter: bile salts (present in mammalian gastrointestinal tracts), sodium dodecyl sulfate (SDS, a common surfactant in cleaning and hygiene products) and four antibiotics (present at variable concentrations in natural and clinical environments). Our results show that bile salts and SDS can reduce the detrimental effect of phages on bacterial growth. In some cases these compounds completely mitigated any negative effects of phages on bacterial growth and consequently bacteria did not evolve resistance to phages in these conditions. The proportional effects of phages were unaffected by antibiotics in most combinations, excepting three cases of phage-drug synergy. These results suggest that accounting for interactions between phages and environmental factors such as surfactants and antibiotics will improve understanding of both bacterial growth and resistance evolution to phages in vivo and in nature.
Regulation of T helper cell differentiation by the interplay between histone modification and chromatin interaction
GEO Series GSE237916. Mus musculus. 197 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other.
Data from: Modification of Escherichia coli–bacteriophage interactions by surfactants and antibiotics in vitro
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HMGB1 prefers to interact with structural RNAs and regulates rRNA methylation modification and translation in HeLa cells
GEO Series GSE120693. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Maternal obesity disrupts histone modifications mediated by Ezh2 and Ampk interactions and induces cell fate defects during embryonic cortical neurogenesis. [ChIP-Seq]
GEO Series GSE255917. Rattus norvegicus. 30 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression
GEO Series GSE122758. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.