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95 results for “intestinal tumor”
Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR]
ClinicalTrials.gov study NCT00700258. IPD Sharing: NO. Countries: 1. Publications: 3.
Diagnostic Performances of Urine and Plasma 5-hydroxyindolacetic Acid (5HIAA) Values in Patients With Small-intestine Neuroendocrine Tumors
ClinicalTrials.gov study NCT02826928. IPD Sharing: Not stated. Countries: 1. Publications: 1.
taVNS Reduces Postoperative Pain and Complications in Patients With Gastric and Intestinal Tumors
ClinicalTrials.gov study NCT06763913. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Role of the Tumor Molecular Profile (CMS), UGT1A1 Genotype and Beta-glucuronidase Activity of the Intestinal Microbiota for Treatment Efficiency, Toxicity, Survival and Quality of Life in Patients
ClinicalTrials.gov study NCT05655780. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Retrospective Study of C-kit Mutation Status in Asian Patients With Advanced Gastro-intestinal Stromal Tumors (GIST) Treated With Imatinib.
ClinicalTrials.gov study NCT01227746. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data from: Paternal B vitamin intake is a determinant of growth, hepatic lipid metabolism and intestinal tumor volume in female Apc1638N mouse offspring
Background The importance of maternal nutrition to offspring health and risk of disease is well established. Emerging evidence suggests paternal diet may affect offspring health as well. Objective In the current study we sought to determine whether modulating pre-conception paternal B vitamin intake alters intestinal tumor formation in offspring. Additionally, we sought to identify potential mechanisms for the observed weight differential among offspring by profiling hepatic gene expression and lipid content. Methods Male Apc1638N mice (prone to intestinal tumor formation) were fed diets containing replete (control, CTRL), mildly deficient (DEF), or supplemental (SUPP) quantities of vitamins B2, B6, B12, and folate for 8 weeks before mating with control-fed wild type females. Wild type offspring were euthanized at weaning and hepatic gene expression profiled. Apc1638N offspring were fed a replete diet and euthanized at 28 weeks of age to assess tumor burden. Results No differences in intestinal tumor incidence or burden were found between male Apc1638N offspring of different paternal diet groups. Although in female Apc1638N offspring there were no differences in tumor incidence or multiplicity, a stepwise increase in tumor volume with increasing paternal B vitamin intake was observed. Interestingly, female offspring of SUPP and DEF fathers had a significantly lower body weight than those of CTRL fed fathers. Moreover, hepatic trigylcerides and cholesterol were elevated 3-fold in adult female offspring of SUPP fathers. Weanling offspring of the same fathers displayed altered expression of several key lipid-metabolism genes. Hundreds of differentially methylated regions were identified in the paternal sperm in response to DEF and SUPP diets. Aside from a few genes including Igf2, there was a striking lack of overlap between these genes differentially methylated in sperm and differentially expressed in offspring. Conclusions In this animal model, modulation of paternal B vitamin intake prior to mating alters offspring weight gain, lipid metabolism and tumor growth in a sex-specific fashion. These results highlight the need to better define how paternal nutrition affects the health of offspring.
Data from: Paternal B vitamin intake is a determinant of growth, hepatic lipid metabolism and intestinal tumor volume in female Apc1638N mouse offspring
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MACROD2 haploinsufficiency promotes chromosome instability and growth of intestinal tumors
GEO Series GSE93514. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Integrated DNA methylation and RNA expression in Small Intestinal neuroendocrine tumors
GEO Series GSE73832. Homo sapiens. 133 samples. Type: Methylation profiling by array.
Alternative poladenylation of tumor suppressor genes in small intestinal neuroendocrine tumors
GEO Series GSE56657. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
CeRNA Expression Profiling Identifies KIT Related circRNAs-miRNA-mRNA Networks in Gastro-intestinal Stromal Tumors
GEO Series GSE131481. Homo sapiens. 6 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Impact of intestinal ERβ on the colon transcriptome during colitis-induced tumor development
GEO Series GSE271135. Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing.
Intestinal IKKa is required for tumor initiation in APC mutant mice
GEO Series GSE101415. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Genes that are differentially expressed by 5AZA treatment and DNMT1 knockdown in intestinal tumor organoid
GEO Series GSE72768. Mus musculus. 4 samples. Type: Expression profiling by array.
Genome-wide analysis of gene expression profile of Intestinal (ILEUM) Tumors from APCmin/+/VP16LXRa vs APCmin/+/VP16
GEO Series GSE44071. Mus musculus. 8 samples. Type: Expression profiling by array.
R-Spondin chromosome rearrangements drive Wnt-dependent tumor initiation and maintenance in the intestine
GEO Series GSE98257. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Drosophila AHR limits tumor growth and stem cell proliferation in the intestine
GEO Series GSE229388. Drosophila melanogaster. 28 samples. Type: Expression profiling by high throughput sequencing.
Comparison of Prox1 expressing and Prox1 knockout intestinal tumors and the effect of A2V+CD40
GEO Series GSE124716. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors
GEO Series GSE115145. Homo sapiens. 651 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
Expression profiling of small intestine neuroendocrine tumors identifies subclasses with clinical relevance, therapeutic target and biomarkers for prognosis
GEO Series GSE65286. Homo sapiens. 43 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.