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235
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ShareScore release 0.9.0
Dataset results
235 results for “intracerebral hemorrhage”
MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage
<p>Supplementary data and code of the article "MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage".</p>
Normobaric Hyperoxia for Intracerebral Hemorrhage
ClinicalTrials.gov study NCT04144868. IPD Sharing: NO. Countries: 1. Publications: 11.
Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation
ClinicalTrials.gov study NCT00224770. IPD Sharing: Not stated. Countries: 4. Publications: 5.
Simvastatin For Intracerebral Hemorrhage Study
ClinicalTrials.gov study NCT00718328. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage
ClinicalTrials.gov study NCT04027049. IPD Sharing: NO. Countries: 1. Publications: 50.
Safety and Tolerability of PF-05230907 in Intracerebral Hemorrhage
ClinicalTrials.gov study NCT02687191. IPD Sharing: NO. Countries: 4. Publications: 1.
MIND: Artemis in the Removal of Intracerebral Hemorrhage
ClinicalTrials.gov study NCT03342664. IPD Sharing: Not stated. Countries: 4. Publications: 1.
Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage
ClinicalTrials.gov study NCT04088630. IPD Sharing: NO. Countries: 1. Publications: 84.
Dutch Intracerebral Hemorrhage Surgery Trial
ClinicalTrials.gov study NCT05460793. IPD Sharing: YES. Countries: 1. Publications: 1.
High-Dose Deferoxamine in Intracerebral Hemorrhage
ClinicalTrials.gov study NCT01662895. IPD Sharing: Not stated. Countries: 2. Publications: 6.
Conivaptan for the Reduction of Cerebral Edema in Intracerebral Hemorrhage- A Safety and Tolerability Study
ClinicalTrials.gov study NCT03000283. IPD Sharing: NO. Countries: 1. Publications: 44.
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
ClinicalTrials.gov study NCT05611918. IPD Sharing: YES. Countries: 1. Publications: 1.
Transcranial Ultrasound Via Sonolucent Cranioplasty After Minimally Invasive Intracerebral Hemorrhage Evacuation
ClinicalTrials.gov study NCT05538286. IPD Sharing: NO. Countries: 1. Publications: 10.
Intracerebral Hemorrhage Deferoxamine Trial - iDEF Ttrial
ClinicalTrials.gov study NCT02175225. IPD Sharing: Not stated. Countries: 2. Publications: 14.
A Pilot Study of Minocycline in Intracerebral Hemorrhage Patients
ClinicalTrials.gov study NCT01805895. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Location specific risk factors for intracerebral hemorrhage: Systematic review and meta-analysis
Open the record for dataset details and reuse information.
Rare missense functional variants at COL4A1 and COL4A2 in sporadic intracerebral hemorrhage
<p><b>Objective</b><br> To test the genetic contribution of rare missense variants in <i>COL4A1</i> and <i>COL4A2</i> in which common variants are genetically associated with sporadic intracerebral hemorrhage (ICH), we performed rare variant analysis in multiple sequencing data for the risk for sporadic ICH.</p> <p><b>Methods</b><br> We performed sequencing across 559Kbp at 13q34 including <i>COL4A1</i> and <i>COL4A2</i> among 2,133 individuals (1,055 ICH cases; 1,078 controls) in US-based and 1,492 individuals (192 ICH cases; 1,300 controls) from Scotland-based cohorts, followed by sequence annotation, functional impact prediction, genetic association testing, and <i>in silico</i> thermodynamic modeling.</p> <p><b>Results</b><br> We identified 107 rare nonsynonymous variants in sporadic ICH, of which 2 two missense variants, rs138269346 (COL4A1<sup>I110T</sup>) and rs201716258 (COL4A2<sup>H203L</sup>), were predicted to be highly functional and occurred in multiple ICH cases but not in controls from the US-based cohort. The minor allele of rs201716258 was also present in Scottish ICH patients, and rs138269346 was observed in two ICH-free controls with a history of hypertension and myocardial infarction. Rs138269346 was nominally associated with non-lobar ICH risk (P=0.05), but not with lobar ICH (P=0.08), while associations between rs201716258 and ICH subtypes were non-significant (P>0.12). Both variants were considered pathogenic based on minor allele frequency (<0.00035 in EUR), predicted functional impact (<i>deleterious</i> or <i>probably</i> <i>damaging</i>), and <i>in silico</i> modeling studies (substantially altered physical length and thermal stability of collagen).</p> <p><b>Conclusions</b><br> We identified rare missense variants in <i>COL4A1</i>/<i>A2</i> in association with sporadic ICH. Our annotation and simulation studies suggest that these variants are highly functional and may represent targets for translational follow-up.</p>
China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH）
ClinicalTrials.gov study NCT05975398. IPD Sharing: NO. Countries: 1. Publications: 27.
Etiology and Prognostic Risk Factors of Intracerebral Hemorrhage in Beijing
ClinicalTrials.gov study NCT02350010. IPD Sharing: Not stated. Countries: 1. Publications: 7.
MOBILE Health Intervention in IntraCerebral Hemorrhage Survivors
ClinicalTrials.gov study NCT05830305. IPD Sharing: Not stated. Countries: 1. Publications: 2.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.