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100 results for “ionome”
Raw data for the article "The role of ionomers in the electrolyte management of zero-gap MEA-based CO2 electrolysers: A Fumion vs. Nafion comparison''
<p>Raw data for the article "The role of ionomers in the electrolyte management of zero-gap MEA-based CO2 electrolysers: A Fumion vs. Nafion comparison'', published in Applied Catalysis B: Environmental 2023 335:122885, doi: <a href="https://doi.org/10.1016/j.apcatb.2023.122885">10.1016/j.apcatb.2023.122885</a></p> <p>Folder names describe the type of data content.</p>
Dynamic sparse X-ray nanotomography reveals ionomer hydration mechanism in polymer electrolyte fuel-cell catalyst: Raw data and reconstruction software
<pre>Dynamic sparse X-ray nanotomography reveals ionomer hydration mechanism in polymer electrolyte fuel-cell catalyst: Raw data and reconstruction software Dataset structure: <strong>- Dynamic_PEFC_data.h5</strong> # Raw projection data for dynamic tomography imaging of PEFC catalyst hydration. - /sinogram # Sinogram of all projections, 3-dimensional array with axes (Nangle,X axis,Y axis). - /tomo_angle # Tomography rotation angle for each projection, 1D array with axis (Nangle). - /humidity_readout # Relative humidity value at the time each projection is measured, 1D array with axis (Nangle). - /Deform_X # X/Y/Z components for the deformation vector field which characterize nonrigid deformation of the sample. - /Deform_Y - /Deform_Z <strong>- liquid_simulation.h5</strong> # Numerical simulation of dynamic liquid filling process. - /sinogram # Sinogram of all projections, 3-dimensional array with axes (Nangle,X axis,Y axis). - /tomo_angle # Tomography rotation angle for each projection, 1D array with axis (Nangle). - /groundtruth_tomograms # Ground truth of the simulated tomograms, 4-dimensional array with axes (Timeframe,Y axis, Z axis, X axis). <strong>- phasetran_simulation.h5</strong> # Numerical simulation of gradual linear density change process. - /sinogram # Sinogram of all projections, 3-dimensional array with axes (Nangle,X axis,Y axis). - /tomo_angle # Tomography rotation angle for each projection, 1D array with axis (Nangle). - /groundtruth_tomograms # Ground truth of the simulated tomograms, 4-dimensional array with axes (Timeframe,Y axis, Z axis, X axis). Reconstruction codes: <strong>- astra_nonrigid.zip</strong> # Compressed python package of modified version of astra-toolbox with nonrigid computed tomography implementation. - /astra # Python package folder, need to be added to Python import search path (sys.path). # If the pre-compiled version doesn't work, source code of the pacakge can be downloaded: # https://github.com/zr-gao/astra-toolbox-nonrigid # Follow the instructions and requirements on the website to compile and install the package. <strong>- reconstruction_PEFC.py</strong> # Python script for sparse dynamic tomography of the PEFC dataset. # Need to be in the same folder with Dynamic_PEFC_data.h5 to load data. # Follow the instructions in the code to set reconstruction parameters and export results. # Requirements: cupy, numpy, astra(with nonrigid)*, h5py # * <strong>!!!</strong> Nonrigid computed tomography is used for the reconstruction, therefore the astra package with nonrigid implementation (in astra_nonrigid.zip) is required. <strong>- reconstruction_simulation.py</strong> # Python script for sparse dynamic tomography of numerical simulations. # Need to be in the same folder with liquid_simulation.h5 or phasetran_simulation.h5, loaded filename is selected in the code. # Follow the instructions in the code to set reconstruction parameters and export results. # Requirements: cupy, numpy, astra**, h5py # ** Reconstruction of numerical simulations does not use nonrigid computed tomography, therefore both the astra_nonrigid.zip and the official astra-toolbox package will work. # To download and install the official astra-toolbox refer to the repository: # https://github.com/astra-toolbox/astra-toolbox</pre>
Ionome analysis of Salmonella mutants by Inductively coupled plasma mass spectrometry (ICP-MS)
<p>In many Gram-negative bacteria, the stress sigma factor of RNA polymerase, σS/RpoS, remodels global gene expression to reshape the physiology of quiescent cells and ensure their survival under non-optimal growth conditions. In the foodborne pathogen <i>Salmonella enterica</i> serovar Typhimurium, σS is also required for biofilm formation and virulence.</p><p>We have previously shown that a Δ<i>rpoS</i> mutation affects the <i>Salmonella</i> ionome. Indeed, inductively coupled plasma mass spectrometry analyses have unraveled a significant effect of the Δ<i>rpoS </i>mutation on the cellular concentration of manganese, magnesium, cobalt and potassium, suggesting that σS controls fluxes of ions that might be important for the fitness of quiescent cells (Metaane et al. 2022, PLoS ONE 17(3): e0265511).</p><p>Study: These findings prompted us to evaluate the impact on the<i> Salmonella</i> ionome of deletions of genes encoding the <i>Salmonella</i> Mn2+ transporters (<i>sitABCD</i> and <i>mntH</i>), the Co2+ transporter (<i>cbiMNQO</i> operon) and small proteins of unkown function (<i>yqaE</i> and <i>yqjDEK</i>) that accumulate in quiescent <i>Salmonella</i> under the tight control of σS (Levi-Meyrueis et al. PloS one. 2014; 9(5):e96918, Lago et al. Scientific reports. 2017; 7(1):2127 and Metaane et al. 2022, PLoS ONE 17(3): e0265511).</p><p>Material and Methods: Cell-associated contents of several elements were measured by inductively coupled plasma mass spectrometry (ICP-MS) as previously described in Metaane <i>et al </i>2022 PLoS ONE 17(3): e0265511.Dried cell pellets were prepared by V. Monteil and F. Norel (Institut Pasteur, Université de Paris, CNRS UMR3528, Biochimie des Interactions Macromoléculaires, F-75015, Paris, France). Cell-associated contents of several elements were measured by S. Ayrault and L. Bordier (ICP-MS platform, Laboratoire des Sciences du Climat et de l'Environnement, LSCE/IPSL, CEA-CNRSUVSQ,Université Paris-Saclay, 91191, Gif-sur-Yvette, France)</p><p><strong>This work was supported by the French National Research Agency (ANR-19-CE44-0005-01, PERIOMET project).</strong></p><p><strong>Linked studies:</strong></p><ul><li>NOREL Francoise, MONTEIL Veronique, DOUCHE Thibaut, & MATONDO Mariette. (2023). Global effects of deletions of the sitABCD, mntH, cbiMNQO and corA genes, encoding transporters for manganese, cobalt and magnesium on protein abundance in Salmonella enterica serovar Typhimurium grown to stationary phase in LB. [Data set]. Zenodo. https://doi.org/10.5281/zenodo.8279780</li><li>Metaane S, Monteil V, Douché T, Giai Gianetto Q, Matondo M, Maufrais C, Norel F. Loss of CorA, the primary magnesium transporter of <i>Salmonella, </i>is alleviated by MgtA and PhoP-dependent compensatory mechanisms. PloS one. 2023;18(9):e0291736.</li></ul>
Kinetochore and ionomic adaptation to whole genome duplication
<p>Whole genome duplication (WGD) brings challenges to key processes like meiosis but nevertheless is associated with diversification in all kingdoms. How is WGD tolerated, and what processes commonly evolve to stabilize the new polyploid lineage? Here we study this in <em>Cochlearia</em> spp., which have experienced multiple rounds of WGD in the last 300,000 years. We first generate a chromosome-scale genome and sequence 113 individuals from 33 diploid, tetraploid, hexaploid, and outgroup populations. We detect the clearest post-WGD selection signatures in functionally interacting kinetochore components and ion transporters. We structurally model these derived selected alleles, associating them with known WGD-relevant functional variation, and compare these results to independent recent post-WGD selection in <em>Arabidopsis</em> <em>arenosa</em> and <em>Cardamine</em> <em>amara</em>. Some of the same biological processes evolve in all three WGDs, but specific genes recruited are flexible. This points to a polygenic basis for modifying systems that control the kinetochore, meiotic crossover number, DNA repair, ion homeostasis, and cell cycle. Given that DNA management (especially repair) is the most salient category with the strongest selection signal, we speculate that the generation rate of structural genomic variants may be altered by WGD in young polyploids, contributing to their occasionally spectacular adaptability observed across kingdoms.</p>
Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries
ClinicalTrials.gov study NCT01129440. IPD Sharing: YES. Countries: 1. Publications: 4.
Kinetochore and ionomic adaptation to whole genome duplication
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Raw mass-standardized ionomic data from seven fish species and raw transcriptome sequences for mosquitofish inhabiting the Tar Creek Superfund Site in OK, USA
<p>Our understanding of the mechanisms mediating the resilience of organisms to environmental change remains lacking. Heavy metals negatively affect processes at all biological scales, yet organisms inhabiting contaminated environments must maintain homeostasis to survive. Tar Creek in Oklahoma, USA, contains high concentrations of heavy metals and an abundance of Western mosquitofish (<em>Gambusia affinis)</em>, though several fish species persist at lower frequency. To test hypotheses about the mechanisms mediating the persistence and abundance of mosquitofish in Tar Creek, we integrated ionomic data from seven resident fish species and transcriptomic data from mosquitofish to test hypotheses about the mechanisms mediating the persistence of mosquitofish in Tar Creek. We predicted that mosquitofish minimize uptake of heavy metals more than other Tar Creek fish inhabitants and induce transcriptional responses to detoxify metals that enter the body, allowing them to persist in Tar Creek at higher density than species that may lack these responses. Tar Creek populations of all seven fish species accumulated heavy metals, suggesting mosquitofish cannot block uptake more efficiently than other species. We found population-level gene expression changes between mosquitofish in Tar Creek and nearby unpolluted sites. Gene expression differences primarily occurred in the gill, where we found upregulation of genes involved with lowering transfer of metal ions from the blood into cells and mitigating free radicals. However, many differentially expressed genes were not in known metal response pathways, suggesting multifarious selective regimes and/or previously undocumented pathways could impact tolerance in mosquitofish. Our systems-level study identified well characterized and putatively new mechanisms that enable mosquitofish to inhabit heavy metal-contaminated environments.</p>
Restoration Repairs Using Composite Resin Versus Glass Ionomer in Primary Molars: a Randomized Clinical Trial
ClinicalTrials.gov study NCT04491981. IPD Sharing: Not stated. Countries: 1. Publications: 17.
Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer
ClinicalTrials.gov study NCT04365270. IPD Sharing: NO. Countries: 1. Publications: 5.
Primary Molars Restorations With Encapsulated or Hand-Mixed Glass Ionomer: Clinical Trial
ClinicalTrials.gov study NCT02274142. IPD Sharing: Not stated. Countries: 1. Publications: 1.
This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affect
ClinicalTrials.gov study NCT06641011. IPD Sharing: YES. Countries: 1. Publications: 0.
Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity
ClinicalTrials.gov study NCT04591444. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Glass Ionomer-Based Fissure Sealants in Children
ClinicalTrials.gov study NCT07388472. IPD Sharing: YES. Countries: 1. Publications: 0.
Assessing Parental Acceptance to Silver Diamine Fluoride Staining Before and After Masking the Colour With Glass Ionomer
ClinicalTrials.gov study NCT04509232. IPD Sharing: NO. Countries: 1. Publications: 12.
Effectiveness of Atraumatic Restorative Treatment Using Glass Ionomer Cement of Different Costs
ClinicalTrials.gov study NCT02778503. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting
ClinicalTrials.gov study NCT06696105. IPD Sharing: NO. Countries: 1. Publications: 5.
Glass Ionomer Cement Sealant in the Prevention of Post-eruptive Fractures in Molars Affected by MIH
ClinicalTrials.gov study NCT03870958. IPD Sharing: NO. Countries: 1. Publications: 6.
Evaluation of Low-shrinkage Giomer Versus Resin-Modified Glass Ionomer in Cervical Caries Lesions: A Clinical Trial
ClinicalTrials.gov study NCT05930548. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Evaluation of High Viscosity Glass Ionomer Strip Crowns in Primary Maxillary Incisors
ClinicalTrials.gov study NCT05838469. IPD Sharing: NO. Countries: 1. Publications: 4.
Cost-efficacy of Atraumatic Restorations (ART) Using Different Encapsulated Glass Ionomer Cement
ClinicalTrials.gov study NCT02730000. IPD Sharing: NO. Countries: 1. Publications: 25.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.