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316
datasets available to search
ShareScore release 0.9.0
Dataset results
316 results for “itraconazole”
Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Ha
ClinicalTrials.gov study NCT02157883. IPD Sharing: YES. Countries: 6. Publications: 1.
A Study to Evaluate Drug-Drug Interaction of TAK-788 With Itraconazole and Rifampin in Healthy Adult Participants
ClinicalTrials.gov study NCT03928327. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study to Investigate the Effect of Itraconazole on the PK of Multiple Doses of Balovaptan in Healthy Volunteers
ClinicalTrials.gov study NCT03579719. IPD Sharing: NO. Countries: 1. Publications: 1.
Itraconazole in Treating Patients With Biochemically Relapsed Prostate Cancer
ClinicalTrials.gov study NCT01787331. IPD Sharing: NO. Countries: 1. Publications: 0.
Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers
ClinicalTrials.gov study NCT03530995. IPD Sharing: NO. Countries: 1. Publications: 1.
Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail.
ClinicalTrials.gov study NCT00356915. IPD Sharing: Not stated. Countries: 7. Publications: 1.
Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer
ClinicalTrials.gov study NCT03994211. IPD Sharing: YES. Countries: 4. Publications: 1.
Endemic Mycoses Treatment With SUBA-itraconazole vs Itraconazole
ClinicalTrials.gov study NCT03572049. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Pilot Biomarker Trial to Evaluate the Efficacy of Itraconazole in Patients w/ Basal Cell Carcinomas
ClinicalTrials.gov study NCT01108094. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors
ClinicalTrials.gov study NCT03077607. IPD Sharing: NO. Countries: 4. Publications: 1.
A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib
ClinicalTrials.gov study NCT03398421. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study to Evaluate the Effect of the Potent Cytochrome P-450 3A4 (CYP3A4) Inhibitor Itraconazole on the Pharmacokinetics (PK) of TAK-954 in Healthy Adult Participants
ClinicalTrials.gov study NCT03173170. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours
ClinicalTrials.gov study NCT01772563. IPD Sharing: NO. Countries: 1. Publications: 1.
Phase II Study of Itraconazole and Pemetrexed in Patients With Previously Treated Non-Squamous NSCLC
ClinicalTrials.gov study NCT00769600. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Data from: Combining derivative and synchronous approaches for simultaneous spectrofluorimetric determination of Terbinafine and Itraconazole.
<p>In this study, determination of terbinafine and itraconazole down to biological concentration level has been carried out. The determination is based on increasing the selectivity of the spectrofluorimetric technique by combining both derivative and synchronous spectrofluorometric approaches which permits successful estimation of terbinafine at 257 and itraconazole at 319 in presence of each other at λ of 60 nm. ICH validation guidelines were followed to fully validate the method, and linearity was obtained for the two drugs over the range of 0.1-0.7 g/mL for terbinafine and 0.5-4.0 g/mL for itraconazole. Application of the method was successfully carried out in the commercial tablets with good agreement with the comparison spectrofluorometric methods. As the detection limits were down to 0.013 and 0.1 g/mL and quantitation limits were 0.04, 0.032 g/mL for terbinafine and itraconazole, respectively; the in-vitro determination of terbinafine and itraconazole in spiked plasma samples was applicable. The percentage recoveries in biological samples were 97.17 ± 4.54 and 98.75 ± 2.25 for Terbinafine and Itraconazole respectively. Water was utilized as the optimum diluting solvent in the proposed methodology which adds an eco-friendly merit.</p>
Factorial design assisted RP-HPLC method for simultaneous determination of fluconazole, itraconazole, and terbinafine
<p>A 2<sup>3</sup> full factorial design model was utilized for development of a new HPLC method with UV detection to estimate three antifungal drugs simultaneously. Fluconazole (FLU), itraconazole (ITR) and terbinafine (TRH), which are co-administered for severe fungal infections have been determined using MOS-1 Hypersil C18 column and an isocratic eluent; methanol 95% and phosphate buffer 5% with 0.001% triethylamine. The pH adjusted 7, and flow rate of 0.7 mL/min. The three drugs were separated within less than 7 minutes at 210 nm. The developed method gave linear response over 5-80, 5-50 and 1-50 μg/mL for FLU, ITR and TRH, respectively. It showed detection limits of 0.8761, 0.293 and 0.1965 μg/mL and quantification limits of 2.655, 0.8788 and 0.5956 μg/mL for the three drugs, respectively. The design of experiment facilitated the optimization of different variables affecting the separation of the three drugs. The designed method sensitivity permitted the simultaneous estimation of ITR and TRH in spiked human plasma successfully.</p>
A Study To Evaluate The Effect Of Itraconazole On Pharmacokinetics Of PF-06463922 In Healthy Volunteers
ClinicalTrials.gov study NCT02838264. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Drug-Drug Interaction Study of the Effect of Rabeprazole, Itraconazole or Fluconazole on the Pharmacokinetics of Vismodegib
ClinicalTrials.gov study NCT01772290. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy of Low-dose Venetoclax With Itraconazole + TACL for R/R ALL Patients
ClinicalTrials.gov study NCT07039877. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Itraconazole for the Prevention of Fungal Infections in Chronic Granulomatous Disease
ClinicalTrials.gov study NCT00001280. IPD Sharing: Not stated. Countries: 1. Publications: 2.
ScienceDex guides
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Allen Brain Atlas
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.