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datasets available to search
ShareScore release 0.9.0
Dataset results
49 results for “lesion model”
Quantification of stroke lesion volume using epidural EEG in a cerebral ischaemic rat model
<p>We have uploaded the dataset of rat EEG in response to the specific sound stimuli. The dataset includes rat EEG of normal subjects (n = 10), mild (n = 7), moderate (n = 7), and severe (n = 7) right auditory cortical infarction subjects. </p> <p>The dataset can be analyzed using MATLAB software. For power spectrum density (PSD) analysis of the data, we used the zero-phase forward and reverse Infinite Impulse Response Butterworth filter of 4th order. Further, we averaged the last 300 ms of the signal before stimulus onset as a baseline correction. Next, we down-sampled the data from 1,200 to 600 Hz. Subsequently, we conducted the PSD analysis using signals obtained from the target stimulus onset to 1 s using Welch’s method, which is one of the most widely used periodogram methods for determining the power density of EEG frequency components. The parameter was set to divide the EEG signals into eight sections of equal length, each with a 50% overlap based on the Hamming window. We defined the frequency range for each band as follows: Delta (1-4 Hz), theta (4-8 Hz), alpha (8-12 Hz), and beta (12-30 Hz). We calculated the relative power for each frequency band by summing all of the absolute PSD values across the four bands to compute the total power followed by dividing the absolute value for each frequency band with the total power. Finally, we calculated the DAR (delta/alpha ratio) and the DTABR ((delta + theta) / (alpha + beta) ratio), which were computed by the relative power of the relevant frequency bands. Further, we analysed AEPs in response to the target sound stimuli by averaging all of the epochs between 300 ms before the stimuli onset to 500 ms after it. The AEP amplitude was defined as the highest recorded voltage following the sound stimulus. The latency of the components of the AEPs was defined as the duration from stimulus onset to the peak amplitude.</p>
Osteolitic vs Osteoblastic metastatic lesion: Computational modeling of fracture risk in the human vertebra after screws fixation procedure
<p>Metastatic lesions compromise the mechanical integrity of vertebrae, increasing the fracture risk. Screwfixation is usually performed to guarantee spinal stability and prevent dramatic fracture events. Accordingly, predicting the overall mechanical response in such conditions is critical to planning and optimizing the surgical treatment. This work proposes an image-basedfinite element computational approach describing the mechanical behavior of a patient-specific instrumented metastatic vertebra by assessing the effect of lesion size, location, type and shape on the fracture load and fracture patterns under physiological loading conditions. A specific constitutive model for the metastasis is integrated to account for the effect of the diseased tissue on the bone material properties. Computational results demonstrate that size, location, and type of metastasis significantly affect the overall vertebral mechanical response, and suggest better account these parameters in estimating the fracture risk. Combining multiple osteolytic lesions to account for irregular shape of the overall metastatic tissue has a not significant effect on fracture load of vertebra macroscopically. In addition, the combination of loading mode and metastasis type is shown for the first time as a critical modeling parameter in determining the fracture risk. The proposed computational approach moves towards defining a clinically integrated tool to improve the management of metastatic vertebrae and quantitatively evaluate fracture risk.</p>
Peptide Pool Instability of Precancerous Lesion in Rats with Model of Chronic Pancreatitis and/or Without Type 1 Diabetes Mellitus
<p><span><strong>Supplementary table 1. </strong>Data of Shapiro-Wilk (W) normality test and Homogeneity of Variance Test (Levene's F Test).</span></p> <p> </p> <p><span><strong>Supplementary table 2. </strong>Kruskal-Wallis as the overall test (H-values) and posthoc Dunn's test with Bonferroni correction. The corrected α using the Bonferroni correction method is 0.017</span></p>
Predicting Tumor Metastasis by Employing a Target Organ/Primary Lesion Fusion Radiomics Model
ClinicalTrials.gov study NCT06202404. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Prediction Model of Pancreatic Neoplasms in CP Patients With Focal Pancreatic Lesions
ClinicalTrials.gov study NCT07045181. IPD Sharing: NO. Countries: 1. Publications: 3.
Pre-planning Mathematical Models in EUS-guided Laser Ablation of Pancreatic Lesions
ClinicalTrials.gov study NCT05549960. IPD Sharing: NO. Countries: 1. Publications: 16.
Ultrasound-based Diagnostic Model for Differentiating Malignant Breast Lesion From Benign Lesion
ClinicalTrials.gov study NCT03080623. IPD Sharing: NO. Countries: 1. Publications: 1.
Study to Validate a Model of Surgical Deescalation in Atypicals Breast Lesions
ClinicalTrials.gov study NCT02523612. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Mathematical modeling for the prediction of cerebral white matter lesions based on clinical examination data
Open the record for dataset details and reuse information.
Exploring the predictive value of lesion topology on motor function outcomes in a porcine ischemic stroke model
<p>Dataset to accompany manuscript currently in review at Scientific Reports (12/17/2020)</p>
Evaluation of Resin Composite Posterior Restorations Using Modeling Resin Insertion Technique in Class I Lesions
ClinicalTrials.gov study NCT05801458. IPD Sharing: Not stated. Countries: 0. Publications: 19.
The Tissue-Engineered Human Psoriatic Skin Substitute: A Valuable In Vitro Model to Identify Genes with Altered Expression in Lesional Psoriasis
GEO Series GSE120464. Homo sapiens. 13 samples. Type: Expression profiling by array.
Continuous ZnO nanoparticle exposure induces melanoma-like skin lesions in epidermal barrier dysfunction model mice through anti-apoptotic effects mediated by the oxidative stress–activated NF-κB path
GEO Series GSE183662. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome Clarifies Mechanisms of Lesion Genesis Versus Progression in Models of Ccm3 Cerebral Cavernous Malformations [RNA-seq]
GEO Series GSE134005. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
GEO Series GSE233866. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic changes in eutopic endometrium and ectopic lesions in mouse model during progression of endometriosis-related infertility
GEO Series GSE240392. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome of senescent and non-senescent cells within PanIN pancreatic premalignant lesions in a KRas-driven mouse model
GEO Series GSE128319. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Modeling epigenetic lesions that cause gliomas [ChIP-Seq]
GEO Series GSE225732. Homo sapiens; Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Low-dose anti-HIV drug efavirenz mitigates retinal vascular lesions in a mouse model of Alzheimer's disease
GEO Series GSE199867. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Modeling epigenetic lesions that cause gliomas
GEO Series GSE225794. Mus musculus; Homo sapiens. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.