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56 results for “leukocyte profile”
Data from: Habitat and seasonal drivers of leukocyte profiles within and across Neotropical bat species
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Data from: Time-keeping programme can explain seasonal dynamics of leukocyte profile in a migrant bird
It has been proposed that immune functioning in wild animals is shaped by the trade-off between a probability of encountering pathogens and an availability of resources for maintaining immune system in active state. Due to resources' seasonality one can expect that immune functioning, e.g., absolute and relative counts of white blood cells, WBC (leukocyte profile) also follows an annual cycle. However, dynamics of the seasonal changes of leukocyte profile are controversial and specific inquiries so far addressed only a portion of annual cycle. To study the seasonal dynamics of the leukocyte profile and to test its possible endogenous basis we experimentally simulated annual cycle in a migratory passerine bird, chiffchaff (Phylloscopus collybita abietinus). We report here a clear seasonal pattern of leukocyte profile in that species. The highest WBC counts were observed during pre-alternate moult and the lowest during the subsequent spring migration; the seasonal dynamics of HL ratio showed the opposite tendency. Surprisingly, HL ratios during autumn migration were relatively low, indicating little to no stress. Observed seasonal changes in controlled experimental conditions suggest an existence of time-keeping programme underlying these variations. Additionally we found negative relationship between the body condition index and WBC counts and positive relationship with HL (heterophil to lymphocyte) ratio; these findings are controversial with the data obtained with other bird species in wild populations. Understanding the origins of variation of leukocyte profile per se and in relation with other parameters of physiological condition can be a useful tool in studying physiological response to environmental changes.
Data from: Leukocyte profiles are associated with longevity and survival, but not migratory effort: a comparative analysis of shorebirds
1. Assessment of leukocyte profiles has become an increasingly popular tool in the fields of ecology and ecophysiology. The ratio of heterophils to lymphocytes (H/L ratio) is of special utility, as it reflects physiological adaptation of an organism to cope either with an infection through injury (via heterophils) or a communicable disease (via lymphocytes). Thus, elevated H/L ratios may constitute an adaptation to risky environments (i.e. associated with high risk of injury). While intra-population variation in avian H/L ratio has been extensively studied, we are aware of no studies that linked this trait to life-history components at the inter-specific level. 2. We measured H/L ratio in over 400 shorebirds from 19 species during their autumn migration through Central Europe. Phylogenetically informed comparative methods were used to test whether H/L ratio was related to: i) annual survival and lifespan; ii) migratory effort, as measured with total migration distance and migratory energy reserves; and iii) confounding variables such as body size or breeding latitude. 3. A relatively strong phylogenetic signal and spatial phylogenetic autocorrelation indicated that most diversification in shorebird H/L ratios occurred relatively early in radiation of this group. 4. Comparative analysis gave strong support for the negative associations of H/L ratio with residual lifespan and annual survival. In contrast, we found no support for the effect of migratory behaviour on H/L ratios, suggesting that leukocyte profiles in shorebirds may not constitute an important physiological adaptation for long-distance migration. 5. Our study provided the first comparative evidence for a link between H/L ratios and important life-history traits in birds. Strong negative associations with annual survival and residual lifespan indicate that leukocyte profiles may form an adaptive basis for life-history strategies in birds.
Data from: Leukocyte profiles are associated with longevity and survival, but not migratory effort: a comparative analysis of shorebirds
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Data from: Time-keeping programme can explain seasonal dynamics of leukocyte profile in a migrant bird
Open the record for dataset details and reuse information.
Figures 1-3 from: Ribeiro PVA, Baesse CQ, Cury MC, de Melo C (2020) Leukocyte profile of the helmeted manakin, Antilophia galeata (Passeriformes: Pipridae) in a Cerrado forest fragment. Zoologia 37: 1-9. https://doi.org/10.3897/zoologia.37.e46441
Figures 1-3 Number of lymphocytes for Antilophia galeata in relation to sex (1), presence/absence of incubation patch (2) and presence/absence of ticks (3). Boxes represent mean values while bars represent the standard error.
Chromatin and gene expression profile at single nuclei level of CD45+ leukocytes from the rhesus brain parenchyma
GEO Series GSE261968. Macaca mulatta. 8 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
In vitro exposure of leukocytes to HIV pre-exposure prophylaxis (PrEP) decreases mitochondrial function and alters gene expression profiles.
GEO Series GSE159339. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profile of peripheral blood leukocytes of 60Co gamma-ray accidently-irradiated persons
GEO Series GSE34131. Homo sapiens. 4 samples. Type: Expression profiling by array.
Maternal influences on the transmission of leukocyte gene expression profiles in population samples (Red Cross Donors)
GEO Series GSE21311. Homo sapiens. 100 samples. Type: Expression profiling by array.
Single-cell transcriptomic profiling of dermal leukocytes
GEO Series GSE223845. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
10x single-cell RNAseq profiling of CD45+ melanoma-infiltrating leukocytes from APOE2 and APOE4 knock-in mice
GEO Series GSE146613. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Effect of exercise on gene expression profile in unfractionated peripheral blood leukocytes
GEO Series GSE18966. Homo sapiens. 20 samples. Type: Expression profiling by array.
Transcriptional profiling of whole blood leukocytes obtained from critically ill patients with sepsis treated with clarithromycin, or not, and healthy particpants
GEO Series GSE196117. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profile of leukocyte RNA from children with steroid sensitive and resistant nephrotic syndrome
GEO Series GSE145969. Homo sapiens. 56 samples. Type: Expression profiling by high throughput sequencing.
Expression profiling of selenium deficiency in mouse colon and splenic leukocytes
GEO Series GSE117027. Mus musculus. 48 samples. Type: Expression profiling by array.
Gene expression profile at single cell level of SiglecF positive bone marrow leukocytes.
GEO Series GSE248716. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis
GEO Series GSE60265. Bos taurus. 16 samples. Type: Expression profiling by high throughput sequencing.
Single-cell profiling reveals a critical role for hypoxia-inducible factor-1a signaling in leukocytes during human craniotomy infection
GEO Series GSE249319. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
DNA methylation profiling of whole blood and reconstructed mixtures of purified leukocytes isolated from human adult blood
GEO Series GSE77797. Homo sapiens. 18 samples. Type: Methylation profiling by genome tiling array.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
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