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48 results for “life course”

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zenodo40/100

Dataset for "Communication with family and friends across the life course"

<p>This is the dataset for "Communication with family and friends across the life course", to be published in PLOS One.</p> <p>The file contains data corresponding to egocentric networks of 3340868 individuals, derived from anonymized call detail records for a 7 months period in the year 2007 from a mobile phone service provider in a European country. Each line in the file corresponds to a different ego-alter pair and provides aggregated voice calling information for the concerned month.</p> <p>Details in README file.</p> <p> </p>

opencc-by-4.0Oct 2016View details →
zenodo40/100

Microspines in tropical climbing plants: a small-scale fix for life in an obstacle course

<p>This dataset is associated to the original research article &quot;Microspines in tropical climbing plants: a small-scale fix for life in an obstacle course&quot; published in the Journal of Experimental Botany.&nbsp;</p> <table> <tbody> <tr> <td>Variable</td> <td>Description</td> <td>Type of variable</td> <td>Units</td> </tr> <tr> <td>sample</td> <td>Sample identifiier</td> <td>Nominal Variable</td> <td>&nbsp;</td> </tr> <tr> <td>sp_code</td> <td>Species identifier</td> <td>Nominal Variable</td> <td>&nbsp;</td> </tr> <tr> <td>sp</td> <td>Species latin name</td> <td>Nominal Variable</td> <td>&nbsp;</td> </tr> <tr> <td>direction</td> <td>Friction test direction</td> <td>Categorical variable</td> <td>&nbsp;</td> </tr> <tr> <td>static_force</td> <td>Force needed to induce motion of the stem segment</td> <td>Continuous variable</td> <td>mN</td> </tr> <tr> <td>sliding_force</td> <td>Force needed to maintain the stem segment in motion</td> <td>Continuous variable</td> <td>mN</td> </tr> <tr> <td>sliding_dist</td> <td>Distance spanned by the stem segment during test</td> <td>Continuous variable</td> <td>mm</td> </tr> <tr> <td>nPeaks</td> <td>Number of force peaks detected during test</td> <td>Discrete variable</td> <td>mN</td> </tr> <tr> <td>peak_frequ</td> <td>Peak frequency during sliding (NPeaks/sliding_dist)</td> <td>Continuous variable</td> <td>peaks.mm<sup>-1</sup></td> </tr> <tr> <td>diam</td> <td>Diameter of the tested segment</td> <td>Continuous variable</td> <td>mm</td> </tr> </tbody> </table> <p>&nbsp;</p>

opencc-by-4.0May 2022View details →
dryad40/100

Subjective well-being across the life course among non-industrialized populations

Open the record for dataset details and reuse information.

publicFeb 2025View details →
dryad36/100

Data from: Eco-evolutionary feedbacks predict the time course of rapid life history evolution

Organisms can change their environment and, in so doing, change the selection they experience and how they evolve. Population density is one potential mediator of such interactions because high population densities can impact the ecosystem and reduce resource availability. At present, such interactions are best known from theory and laboratory experiments. Here we quantify the importance of such interactions in nature by transplanting guppies from a stream where they co-occur with predators into tributaries that previously lacked both guppies and predators. If guppies evolve solely because of the immediate reduction in mortality rate, the strength of selection and rate of evolution should be greatest at the outset then decline as the population adapts to its new environment. If indirect effects caused by the increase in guppy population density in the absence of predation prevail, then there should be a lag in guppy evolution because time is required for them to modify their environment. The duration of this lag is predicted to be associated with the environmental modification caused by guppies. We observed a lag in life history evolution associated with increases in population density and altered ecology. How guppies evolved matched predictions derived from evolutionary theory that incorporates such density effects.

opencc-zeroMay 2019View details →
dryad36/100

Reproductive strategies affect telomere dynamics across the life course

<p>Because parental care has a heritable basis, the benefits of receiving increased parental provisioning early in life are genetically linked to the costs of providing increased parental provisioning at adulthood. Reproductive strategies thus result in distinct cost-benefit syndromes across the life course that may shape individual health and ageing trajectories. Here we used an artificial selection approach in Japanese quail (<em>Coturnix japonica</em>) to test how reproductive strategies affect telomere length, a biomarker of somatic state, at different life stages. We show that males, but not females, from lines selected for low maternal investment (i.e. developing in a relatively small egg) had shorter telomeres at birth. These patterns were still weakly present at the end of the juvenile growth period. In contrast, significantly shorter telomeres were found in reproductively active adult birds from the high investment lines, suggesting that telomere attrition was accelerated in these individuals once they had become reproductively active. Our study shows that reproductive strategies differentially affect telomere dynamics across the life course, highlighting the role of cross-generational constraints in shaping individual ageing trajectories.  </p>

opencc-zeroDec 2020View details →
zenodo36/100

Taking up and terminating leisure-time physical activity over the life course: The role of life events in the familial and occupational life domains

<p>Dataset used for the analyses in the following publication:</p> <p>Lenze, L., Klostermann, C., Lamprecht, M. &amp; Nagel, S. (2021). Taking up and terminating leisure-time physical activity over the life course: The role of life events in the familial and occupational life domains. <em>International Journal of Environmental Research and Public Health</em>, <em>18</em>, 9809. https://doi.org/10.3390/ijerph18189809</p>

opencc-by-4.0Jun 2022View details →
dryad36/100

Hurricanes affect diversification among individual life courses of a primate population

<ol> <li>Extreme climatic events may influence individual-level variability in phenotypes, survival, and reproduction, and thereby drive the pace of evolution. Climate models predict increases in the frequency of intense hurricanes, but no study has measured their impact on individual life courses within animal populations.</li> <li>We used 45 years of demographic data of rhesus macaques to quantify the influence of major hurricanes on reproductive life courses using multiple metrics of dynamic heterogeneity accounting for life course variability and life history trait variances.</li> <li>To reduce intraspecific competition, individuals may explore new reproductive stages during years of major hurricanes, resulting in higher temporal variation in reproductive trajectories. Alternatively, individuals may opt for a single optimal life history strategy due to trade-offs between survival and reproduction.</li> <li>Our results show that heterogeneity in reproductive life courses increased by 4% during years of major hurricanes, despite a 2% reduction in the asymptotic growth rate due to an average decrease in mean fertility and survival, i.e. shortened life courses and reduced reproductive output. In agreement with this, the population is expected to achieve stable population dynamics faster after being perturbed by a hurricane (ρ = 1.512; 95% CI: 1.488, 1.538), relative to ordinary years (ρ = 1.482;1.475,1.490).</li> <li>Our work suggests that natural disasters force individuals into new demographic roles to potentially reduce competition during unfavorable environments where mean reproduction and survival are compromised. Variance in lifetime reproductive success and longevity are differently affected by hurricanes, and such variability is mostly driven by survival. </li> </ol>

opencc-zeroApr 2023View details →
dryad36/100

Data from: Eco-evolutionary feedbacks predict the time course of rapid life history evolution

Open the record for dataset details and reuse information.

publicMay 2019View details →
dryad36/100

Hurricanes affect diversification among individual life courses of a primate population

Open the record for dataset details and reuse information.

publicApr 2023View details →
dryad36/100

Reproductive strategies affect telomere dynamics across the life course

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publicApr 2022View details →
dryad32/100

Data from: Cognition at age 70: life course predictors and associations with brain pathologies

Objective: To investigate predictors of performance on a range of cognitive measures including the Preclinical Alzheimer Cognitive Composite (PACC) and test for associations between cognition and dementia biomarkers in Insight 46, a sub-study of the MRC National Survey of Health and Development. Methods: 502 individuals born in the same week in 1946 underwent cognitive assessment at age 69-71 years, including an adapted version of the PACC and a test of non-verbal reasoning. Performance was characterised with respect to sex, childhood cognitive ability, education and socioeconomic position (SEP). In a sub-sample of 406 cognitively-normal participants, associations were investigated between cognition and β-amyloid (Aβ) positivity (determined from Aβ-PET imaging), whole brain volumes, white matter hyperintensity volumes (WMHV), and APOE-ε4. Results: Childhood cognitive ability was strongly associated with cognitive scores including the PACC more than 60 years later, and there were independent effects of education and SEP. Sex differences were observed on every PACC sub-test. In cognitively-normal participants, Aβ-positivity and WMHV were independently associated with lower PACC scores, and Aβ-positivity was associated with poorer non-verbal reasoning. Aβ-positivity and WMHV were not associated with sex, childhood cognitive ability, education or SEP. Normative data for 339 cognitively-normal Aβ-negative participants are provided. Conclusions: This study adds to emerging evidence that subtle cognitive differences associated with Aβ deposition are detectable in older adults, at an age when dementia prevalence is very low. The independent associations of childhood cognitive ability, education and SEP with cognitive performance aged 70 have implications for interpretation of cognitive data in later life.

opencc-zeroJun 2020View details →
dryad32/100

Offspring sex-ratios are stable across the life-course in Drosophila simulans

Within populations, adult sex ratios influence population growth and extinction risk, mating behaviors and parental care. Additionally, sex ratio adjustment can have pronounced effects on individual fitness. Accordingly, it is important that we understand how often, and why, offspring sex ratios deviate from parity. In Drosophila melanogaster, females appear to improve their fitness by producing fewer sons when paired with older males. However, facultative sex ratio adjustment in D. melanogaster is controversial, and our understanding of how sex ratio skew affects fitness is hampered by pronounced sexual conflict in this species. Additionally, it is unclear if maternal age or quality interact with paternal age to influence offspring sex ratios. Here, we test whether offspring sex ratios vary as a function of maternal quality, and maternal and paternal age in Drosophila simulans, a sister species of D. melanogaster that lacks overt sexual conflict. We find that offspring sex ratios are slightly male biased overall, but constant across the female life-course, and independent of female quality, or paternal age. To really understand if, how and when females skew offspring sex ratios, we need studies linking offspring sex ratios to male and female phenotypes that are predicted to shift optimal investment in sons and daughters.

opencc-zeroSep 2020View details →
ClinicalTrials.gov32/100

Geographical Association Between Basic Life Support Courses, Bystander Cardiopulmonary Resuscitation and Survival

ClinicalTrials.gov study NCT04353089. IPD Sharing: Not stated. Countries: 1. Publications: 9.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Evaluation of Efficacy, Quality of Life and Cost Effectiveness of Short-course Radiotherapy Followed by Capecitabine Plus Oxaliplatin chemotheRapy and TME for High-risk Rectal Cancer (ESCORT Trial)

ClinicalTrials.gov study NCT03676517. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Can Undetectable (Viral Load) = Untransmissible (Virus) Change the Life Course of Adolescents Living in Africa

ClinicalTrials.gov study NCT05278559. IPD Sharing: YES. Countries: 1. Publications: 25.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov32/100

Investigating Food Intake Across the Adult Life Course and Relevant Communication Strategies

ClinicalTrials.gov study NCT06675630. IPD Sharing: NO. Countries: 1. Publications: 4.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov32/100

Group Size in Basic Life Support (BLS) Courses

ClinicalTrials.gov study NCT03773861. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Effects of an Online Meditation Course on Quality of Life

ClinicalTrials.gov study NCT04950543. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Total Energy Expenditure Across the Life Course in Low-and Middle-Income Countries -- Chinese Children

ClinicalTrials.gov study NCT07054294. IPD Sharing: Not stated. Countries: 1. Publications: 2.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

MultiMorbidity Life-Course Approach To Myocardial Health -A Cardiac Sub-Study of the MRC National Survey of Health and Development (NSHD)

ClinicalTrials.gov study NCT05455125. IPD Sharing: NO. Countries: 1. Publications: 2.

closedIPD-NOFeb 2026View details →

ScienceDex guides

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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