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22 results for “long-lasting effects”
Post-hypnotic safety suggestion improves stress coping with long-lasting effects
<p>Effective coping with acute stress is important to promote mental health and to build stress resilience. Interventions improving stress coping usually require long training periods. In this study, we present a hypnosis-based intervention that produces long-term effects after a single hypnosis session. In that session, we established a post-hypnotic safety suggestion that participants can activate afterwards with a cue. We tested 60 participants in our study who all received the hypnosis session and a stress task. The safety group used the post-hypnotic safety cue during acute stress (Trier Social Stress Test, TSST). The control group used a neutral trigger instead. We measured subjective stress responses via self-reports and physiological stress responses via saliva and blood samples as well as heart rate. One week later, all participants filled in an online survey to measure long-term effects of the post-hypnotic safety suggestion. We found that participants using the post-hypnotic safety cue during the TSST reported significantly lower stress compared to the control group. The safety group also reported significantly fewer negative thoughts concerning their TSST performance than the control group during the stress recovery phase and one week later. All participants indicated that the post-hypnotic safety suggestion still worked one week after its establishment. Suggestibility did not affect the efficacy of the post-hypnotic safety suggestion. Our findings demonstrate that post-hypnotic safety suggestions improve stress coping with long-lasting effects, which makes it a promising intervention to promote mental health and establish stress resilience in just one hypnosis session.</p> <p>The manuscript is published in Scientific Reports on February 12, 2024 and available here: https://doi.org/10.1038/s41598-024-54071-3</p>
Repeatedly experiencing the McGurk effect induces long-lasting changes in auditory speech perception
<p>In the McGurk effect, presentation of incongruent auditory and visual speech evokes a fusion percept different than either component modality. We show that repeatedly experiencing the McGurk effect for 14 days induces a change in auditory-only speech perception: the auditory component of the McGurk stimulus begins to evoke the fusion percept, even when presented on its own without accompanying visual speech. This perceptual change, termed fusion-induced recalibration (FIR), was talker-specific and syllable-specific and persisted for a year or more in some participants without any additional McGurk exposure. Participants who did not experience the McGurk effect did not experience FIR, showing that recalibration was driven by multisensory prediction error. A causal inference model of speech perception incorporating multisensory cue conflict accurately predicted individual differences in FIR. Just as the McGurk effect demonstrates that visual speech can alter the perception of auditory speech, FIR shows that these alterations can persist for months or years. The ability to induce seemingly permanent changes in auditory speech perception will be useful for studying plasticity in brain networks for language and may provide new strategies for improving language learning.</p>
Post-hypnotic suggestion improves confidence and speed of memory access with long-lasting effects
<p>The attempt to improve memory has a long tradition. Previous studies do not provide clear evidence concerning the longevity of memory-improving effects which is crucial for clinical applications. In our study, we use the post-hypnotic suggestion of easy remembering to establish long-lasting effects, as post-hypnotic suggestions can be activated with a cue after the hypnotic state. We tested 24 highly suggestible participants in an online study. Participants learned word lists and recalled them later in a recognition memory task where both learned and new words were presented and participants rated their recognition confidence. At the beginning of the study, participants were hypnotized and the post-hypnotic suggestion to remember easily was associated with a cue that participants used during the recognition memory task in the easy-remembering condition. In a control condition, the same participants used a neutral cue. One week later, participants repeated both conditions with new word lists, relying on the same post-hypnotic suggestion they received the week before.</p> <p>Participants were significantly faster and more confident in their recognition ratings in the easy-remembering condition compared to the control condition, and this effect persisted over one week. Crucially, the increased speed and confidence in the easy-remembering condition did not affect memory accuracy; numerically, participants were even slightly better at discriminating old from new words in the easy-remembering condition. These findings demonstrate that post-hypnotic suggestions of easy remembering improve recognition confidence and speed with long-lasting effects, which makes it a promising intervention for patients experiencing subjective memory impairments.</p> <p>All experimental files to run the study in Gorilla are accessible via this link: https://app.gorilla.sc/openmaterials/430668</p>
Repeatedly experiencing the McGurk effect induces long-lasting changes in auditory speech perception
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Data from: A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: a replicated, randomized controlled clinical trial
Purpose: Animal studies have demonstrated anti-inflammatory, and anti-nociceptive properties of hyperbaric oxygen therapy (HBOT). However, physiological data are scarce in humans. In a recent experimental study, the authors used the burn injury (BI) model observing a decrease in secondary hyperalgesia area (SHA) in the HBOT-group compared to a control-group.Surprisingly, a long-lasting neuroplasticity effect mitigating the BI-induced SHA-response was seen in the HBOT-preconditioned group. The objective of the present study, therefore, was to confirm our previous findings using an examiner-blinded, block-randomized, controlled, crossover study design. Patients and methods: Nineteen healthy subjects attended two BI-sessions with an inter-session interval of ≥28 days. The BIs were induced on the lower legs by a contact thermode (12.5 cm2, 47C°, 420 s). The subjects were block-randomized to receive HBOT (2.4 ATA, 100% O2, 90 min) or ambient conditions ([AC]; 1 ATA, 21% O2), dividing cohorts equally into two sequence allocations: HBOT-AC or AC-HBOT. All sensory assessments performed during baseline, BI, and post-intervention phases were at homologous time points irrespective of sequence allocation. The primary outcome was SHA, comparing interventions and sequence allocations. Data are mean (95% CI). Results: During HBOT-sessions a mitigating effect on SHAs was demonstrated compared to AC-sessions, ie, 18.8 (10.5–27.0) cm2 vs 32.0 (20.1–43.9) cm2 (P=0.021), respectively. In subjects allocated to the sequence AC-HBOT a significantly larger mean difference in SHA in the AC-session vs the HBOT-session was seen 25.0 (5.4–44.7) cm2 (P=0.019). In subjects allocated to the reverse sequence, HBOT-AC, no difference in SHA between sessions was observed (P=0.55), confirming a preconditioning, long-lasting (≥28 days) effect of HBOT. Conclusion: Our data demonstrate that a single HBOT-session compared to control is associated with both acute and long-lasting mitigating effects on BI-induced SHA, confirming central anti-inflammatory, neuroplasticity effects of hyperbaric oxygen therapy.
Data from: Long-lasting effects of logging on beetles in hollow oaks
There is growing evidence that biodiversity is important for ecosystem functions. Thus, identification of habitat requirements essential for current species richness and abundance to persist is crucial. Hollow oaks (Quercus spp.) are biodiversity hot spots for deadwood‐dependent insect species, and the main objective of this paper was to test the effect of habitat history and current habitat distribution at various spatial scales on the associated beetle community. We used a gradient spanning 40 km from the coast to inland areas reflecting historical logging intensity (later and lower intensities inland) through 500 years in Southern Norway, to investigate whether the historical variation in oak density is influencing the structure of beetle communities in hollow oaks today. We trapped beetles in 32 hollow oaks along this gradient in forested and seminatural landscapes over two summers. We found higher species richness and total abundance inland consistent with our expectation based on historic logging intensity. Scale‐specific environmental variables also affected the response; beetle abundances were controlled by local conditions, whereas beetle species richness responded to habitat on the landscape scale. This indicates that long time continuity as well as large areas of favorable habitat is necessary to maintain beetle species richness through time in these highly long‐lasting structures.
Effect of Long-lasting Adaptation to Endurance and Speed-power Training on Plasma Free Amino Acids Concentration
ClinicalTrials.gov study NCT05672758. IPD Sharing: YES. Countries: 1. Publications: 34.
The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) on Headache, Cranial Hemodynamic and Autonomic Symptoms in Healthy Volunteers
ClinicalTrials.gov study NCT03989817. IPD Sharing: NO. Countries: 1. Publications: 2.
Effects of Long-lasting Bicarbonate-Sulfate-Calcium-Magnesium Water Intake on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Related Outcome
ClinicalTrials.gov study NCT07211113. IPD Sharing: NO. Countries: 1. Publications: 1.
The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) in Episodic Migraine Patients
ClinicalTrials.gov study NCT04260035. IPD Sharing: NO. Countries: 1. Publications: 2.
Data from: Long-lasting effects of logging on beetles in hollow oaks
Open the record for dataset details and reuse information.
Data from: A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: a replicated, randomized controlled clinical trial
Open the record for dataset details and reuse information.
Single cell RNAseq analysis revealed long-lasting adverse effects of prenatal tamoxifen administration on neurogenesis
GEO Series GSE152125. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Long-lasting effect of jasmonic acid (JA) seedling treatment on the transcriptional response to JA challenge of five-week-old Arabidopsis thaliana (ecotype Col-0).
GEO Series GSE163270. Arabidopsis thaliana. 16 samples. Type: Expression profiling by high throughput sequencing.
Brain transcriptome analysis of Arid1b heterozygote mutation and long-lasting effects of early chronic fluoxetine treatment for mutant mice [RNA-Seq]
GEO Series GSE189653. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Myelin-Associated Oligodendrocytic Basic Protein-Dependent Myelin Repair Confers the Long-lasting Antidepressant Effect of Ketamine
GEO Series GSE214861. Mus musculus. 4 samples. Type: Other.
An Open-label, Multidose Dose-escalation Study to Understand the Safety of CRISPR Gene-editing Therapy and Its Long-Lasting Effects in DMD Patients (MUSCLE)
ClinicalTrials.gov study NCT06594094. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease
ClinicalTrials.gov study NCT05132166. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Long-lasting Effects of Repetitive Neck Muscle Vibrations on Postural Disturbances in Standing Position in Chronic Stroke Patients
ClinicalTrials.gov study NCT03112616. IPD Sharing: NO. Countries: 1. Publications: 0.
Intermittent neonatal hypoxia elicits the upregulation of inflammatory-related genes in the adult rat through long-lasting programming effects
GEO Series GSE74145. Rattus norvegicus. 8 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.