Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
34
datasets available to search
ShareScore release 0.9.0
Dataset results
34 results for “luminal epithelial cells”
GTEx analysis for the paper entitled: The histone variant H2A.J is enriched in luminal epithelial gland cells
<p>H2A.J is a poorly studied mammalian-specific variant of histone H2A. We used immunohistochemistry to study its localization in various human and mouse tissues. H2A.J showed cell-type specific expression with a striking enrichment in luminal epithelial cells of multiple glands including those of breast, prostate, pancreas, thyroid, stomach, and salivary glands. H2A.J was also highly expressed in many carcinoma cell lines and in particular, those derived from luminal breast and prostate cancer. H2A.J thus appears to be a novel marker for luminal epithelial cancers. Knocking-out the H2AFJ gene in T47D luminal breast cancer cells reduced the expression of several estrogen-responsive genes which may explain its putative tumorigenic role in luminal-B breast cancer.</p>
Mammary single-cell RNA-seq analysis and prostate cancer survival as a function of H2AFJ expression for the paper entitled: The histone variant H2A.J is enriched in luminal epithelial cells
<p>H2A.J is a poorly studied mammalian-specific variant of histone H2A. We used immunohistochemistry to study its localization in various human and mouse tissues. H2A.J showed cell-type specific expression with a striking enrichment in luminal epithelial cells of multiple glands including those of breast, prostate, pancreas, thyroid, stomach, and salivary glands. H2A.J was also highly expressed in many carcinoma cell lines and in particular, those derived from luminal breast and prostate cancer. H2A.J thus appears to be a novel marker for luminal epithelial cancers. Knocking-out the H2AFJ gene in T47D luminal breast cancer cells reduced the expression of several estrogen-responsive genes which may explain its putative tumorigenic role in luminal-B breast cancer.</p>
Transcriptome analysis of T47D cells and H2A.J-KO derivatives for the paper entitled: The histone variant H2A.J is enriched in luminal epithelial gland cells
<p>H2A.J is a poorly studied mammalian-specific variant of histone H2A. We used immunohistochemistry to study its localization in various human and mouse tissues. H2A.J showed cell-type specific expression with a striking enrichment in luminal epithelial cells of multiple glands including those of breast, prostate, pancreas, thyroid, stomach, and salivary glands. H2A.J was also highly expressed in many carcinoma cell lines and in particular, those derived from luminal breast and prostate cancer. H2A.J thus appears to be a novel marker for luminal epithelial cancers. Knocking-out the H2AFJ gene in T47D luminal breast cancer cells reduced the expression of several estrogen-responsive genes which may explain its putative tumorigenic role in luminal-B breast cancer.</p>
Dataset for "Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer"
<p>Processed single cell whole genome sequencing data from:</p> <p>Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer Williams, Vinci Oliphant et al 2024</p> <p>Included are processed copy number profiles for all cells included in the study.</p>
Gene expression profiling of Trop2+ and Trop2- luminal epithelial cells and stromal cells from young adult and old mouse prostates
GEO Series GSE128724. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
AR interacts with GATA3 to induce a luminal epithelial phenotype in breast cancer through regulation of lineage-restricted genes [ER-positive_cell_line_GATA3_ChIP-seq]
GEO Series GSE178253. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
AR interacts with GATA3 to induce a luminal epithelial phenotype in breast cancer through regulation of lineage-restricted genes [ER-positive cell line RNA-seq]
GEO Series GSE176005. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells
GEO Series GSE157333. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiling of basal and luminal epithelial cells from young adult and old mouse prostates
GEO Series GSE122367. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Immortalized breast epithelial cell lines from normal breast with luminal and intrinsic subtypes – enriched gene expression
GEO Series GSE108541. Homo sapiens. 59 samples. Type: Expression profiling by high throughput sequencing.
AR interacts with GATA3 to induce a luminal epithelial phenotype in breast cancer through regulation of lineage-restricted genes [ER-negative_cell_line_ChIP-seq]
GEO Series GSE178248. Homo sapiens. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ATAC-Seq chromatin profiling of Suz12-deleted or wild-type organoids derived from basal or luminal mouse mammary epithelial cells
GEO Series GSE116430. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
RNA-seq expression profiling of Suz12-deleted or wild-type organoids derived from basal or luminal mouse mammary epithelial cells.
GEO Series GSE107626. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
RNA-Seq data for Trp53/Brca1-null premalignant mammary epithelial cells with a K8+ luminal origin
GEO Series GSE126761. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state
GEO Series GSE58423. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells
GEO Series GSE153309. Homo sapiens. 10 samples. Type: Methylation profiling by high throughput sequencing.
Single cell RNA-seq of basal, luminal and total epithelial cells from the mammary glands of female mice
GEO Series GSE98131. Mus musculus. 1566 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq and ATAC-Seq profiling of Suz12-deleted or wild-type organoids derived from basal or luminal mouse mammary epithelial cells
GEO Series GSE116431. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
RNA-sequencing of luminal epithelial cells from adult murine mammary glands.
GEO Series GSE268540. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
AR interacts with GATA3 to induce a luminal epithelial phenotype in breast cancer through regulation of lineage-restricted genes [ER-negative cell line RNA-seq]
GEO Series GSE176006. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.