Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
381
datasets available to search
ShareScore release 0.9.0
Dataset results
381 results for “lung carcinoma”
Altered nanoparticle uptake by lung carcinoma cells when stimulated with epidermal growth factor
<p>This dataset provides the raw data supporting the paper "Altered nanoparticle uptake by lung carcinoma cells when stimulated with epidermal growth factor". The focus of the study was to investigate the uptake of two different sizes of silica NPs and gold NPs in lung epithelial cells A549 in the presence of epidermal growth factor (EGF). </p> <p>The data set includes:</p> <ul> <li>Screening for EGF receptor using western blot and confocal microscopy (Figure 1 and Figure S1)</li> <li>Investigating expression of RAC1/CDC42 proteins upon EGF stimulation using Western blot (Figure 2)</li> <li>Investigating expression of RAC1 gene upon EGF stimulation using RT-qPCR (Figure S2)</li> <li>Evaluating uptake of endocytic markers upon EGF stimulation using confocal laser scanning microscopy (Figure 3, Figure S4) and flow cytometry (Figure 3)</li> <li>Nanoparticle characterization using TEM (Figure 4, Figure S6) and UV-Vis (Figure S5, Figure S6)</li> <li>Evaluating silica nanoparticle uptake upon EGF stimulation using confocal laser scanning microscopy (Figure 5, Figure S8) and flow cytometry (Figure 5)</li> <li>Evaluating gold nanoparticle uptake upon EGF stimulation using dark-field microscopy and ICP-AES (Figure 6)</li> <li>Investigating expression of c-MYC gene upon EGF stimulation using RT-qPCR (Figure 6)</li> <li>Cell viability results, analysed via lactate dehydrogenase assay (Figure S3) and MTS assay (Figure S9)</li> <li>Raw integrated density data from dark-field images (Figure S9)</li> </ul>
Exploring NSD3 Driven Gene Expression Profiles in Lung Squamous Cell Carcinoma
<p><strong>SGC Open Notebook Project to Characterize the HMTase NSD3</strong></p> <p><strong>Exp026 Objective:</strong> NSD3 is frequently amplified as part of the 8p11-12 focal amplification in several types of cancer. Here we set out to explore the gene expression profiles of NSD3 amplified versus non-amplified lung squamous cancer samples from the TCGA. However, because this event takes place in the context of a focal amplification we will also compare samples with high versus low NSD3 expression. The goal of this experiment is to identify putative oncogenic signalling pathways NSD3 may regulate, as well as inform on the biological role of this protein in the context of gene expression. </p>
Assessment of changes in circRNA expression based on transcripts of genes encoding ADAMTS proteins in patients with non-small cell lung carcinoma compared to normal tissue
Open the record for dataset details and reuse information.
Testing Afatinib in Combination With Pembrolizumab in Patients With Squamous Cell Carcinoma of the Lung
ClinicalTrials.gov study NCT03157089. IPD Sharing: UNDECIDED. Countries: 5. Publications: 2.
A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors
ClinicalTrials.gov study NCT02573259. IPD Sharing: NO. Countries: 7. Publications: 3.
A Study of LY2510924 in Participants With Extensive-Stage Small Cell Lung Carcinoma
ClinicalTrials.gov study NCT01439568. IPD Sharing: YES. Countries: 1. Publications: 2.
Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Metastatic Small Cell Lung Carcinoma
ClinicalTrials.gov study NCT00483509. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of Erlotinib (Tarceva) After Surgery With or Without Adjuvant Chemotherapy in Non-Small Cell Lung Carcinoma (NSCLC) Patients Who Have Epidermal Growth Factor Receptor (EGFR) Positive Tumors
ClinicalTrials.gov study NCT00373425. IPD Sharing: Not stated. Countries: 19. Publications: 1.
A Phase I/Ib Study of MEK162, a MEK Inhibitor, in Combination With Carboplatin and Pemetrexed in Patients With Non-squamous Carcinoma of the Lung
ClinicalTrials.gov study NCT02185690. IPD Sharing: Not stated. Countries: 1. Publications: 21.
A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas
ClinicalTrials.gov study NCT00923481. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Investigation of GSK2879552 in Subjects With Relapsed/Refractory Small Cell Lung Carcinoma
ClinicalTrials.gov study NCT02034123. IPD Sharing: YES. Countries: 3. Publications: 1.
Small Cell Lung Carcinoma Trial With Nivolumab and IpiliMUmab in LImited Disease
ClinicalTrials.gov study NCT02046733. IPD Sharing: NO. Countries: 8. Publications: 3.
Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas
ClinicalTrials.gov study NCT02192541. IPD Sharing: NO. Countries: 1. Publications: 4.
Study CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC)
ClinicalTrials.gov study NCT02771626. IPD Sharing: NO. Countries: 1. Publications: 1.
Study to Evaluate Treatment Customized According to RAP80 and BRCA1 in Patients With Advanced Lung Carcinoma
ClinicalTrials.gov study NCT00617656. IPD Sharing: NO. Countries: 1. Publications: 2.
Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional Recu
ClinicalTrials.gov study NCT00915005. IPD Sharing: Not stated. Countries: 1. Publications: 4.
ABC-lung: Atezolizumab, Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung Carcinoma
ClinicalTrials.gov study NCT04245085. IPD Sharing: UNDECIDED. Countries: 5. Publications: 1.
NIvolumab COmbination With Standard First-line Chemotherapy and Radiotherapy in Locally Advanced Stage IIIA/B Non-Small Cell Lung Carcinoma
ClinicalTrials.gov study NCT02434081. IPD Sharing: NO. Countries: 5. Publications: 2.
AZD9291 Versus Placebo in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy.
ClinicalTrials.gov study NCT02511106. IPD Sharing: YES. Countries: 25. Publications: 13.
BAY43-9006 - Phase II Study in Non-Small Cell Lung Carcinoma (NSCLC)
ClinicalTrials.gov study NCT00101413. IPD Sharing: Not stated. Countries: 2. Publications: 2.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.