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6 results for “marine metabolomics”
Plasma NMR metabolomic of rainbow trout fed diets with different levels of marine and plant ingredients.
<p>The NMR and biochemical datasets used in the manuscript draft entiteld "Intestinal microbiota in rainbow trout, <em>Oncorhynchus mykiss</em>, fed diets with different levels of marine and plant ingredients: A correlative approach with some plasma metabolites."</p> <p>François-Joël Gatesoupe1*, Benoît Fauconneau1, Catherine Deborde2,3**, Blandine Madji Hounoum1,2, Daniel Jacob2,3,Annick Moing2,3, Geneviève Corraze1, Françoise Médale1. 1 UMR 1419 NuMeA, INRA, Université de Pau et des Pays de l’Adour, Saint Pée sur Nivelle, France 2 Bordeaux Metabolome Facility, CGFB, MetaboHUB, Centre INRA Nouvelle -Aquitaine-Bordeaux, Villenave d'Ornon, France 3 UMR1332 Biologie du Fruit et Pathologie, Centre INRA Nouvelle -Aquitaine-Bordeaux, Villenave d'Ornon, France<br> *Corresponding author Joel.Gatesoupe@partenaire-exterieur.ifremer.fr</p> <p>**NMR dataset Corresponding author catherine.deborde@inra.fr</p> <p> </p> <p> </p> <p> </p>
Data from: Expanding the described metabolome of the marine cyanobacterium Moorea producens JHB through orthogonal natural products workflows
Moorea producens JHB, a Jamaican strain of tropical filamentous marine cyanobacteria, has been extensively studied by traditional natural products techniques. These previous bioassay and structure guided isolations led to the discovery of two exciting classes of natural products, hectochlorin (1) and jamaicamides A (2) and B (3). In the current study, mass spectrometry-based 'molecular networking' was used to visualize the metabolome of Moorea producens JHB, and both guided and enhanced the isolation workflow, revealing additional metabolites in these compound classes. Further, we developed additional insight into the metabolic capabilities of this strain by genome sequencing analysis, which subsequently led to the isolation of a compound unrelated to the jamaicamide and hectochlorin families. Another approach involved stimulation of the biosynthesis of a minor jamaicamide metabolite by cultivation in modified media, and provided insights about the underlying biosynthetic machinery as well as preliminary structure-activity information within this structure class. This study demonstrated that these orthogonal approaches are complementary and enrich secondary metabolomic coverage even in an extensively studied bacterial strain.
Data from: Expanding the described metabolome of the marine cyanobacterium Moorea producens JHB through orthogonal natural products workflows
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Supplemental Tables for Heal et al: Marine community metabolomes carry fingerprints of phytoplankton community composition
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2D-LC-MS/MS based non-targeted metabolomics of marine DOM (.raw files)
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2D-LC-MS/MS based non-targeted metabolomics of marine DOM (.mzML files)
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