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Dataset results
126 results for “mechanical signaling”
An Open-access Database for the Evaluation of Cardio-mechanical Signals from Patients with Valvular Heart Diseases
<p>This dataset is for the paper "An Open-access Database for the Evaluation of Cardio-mechanical Signals from Patients with Valvular Heart Diseases" published to Frontiers in Physiology. Please cite "Yang C, Fan F, Aranoff N, Green P, Li Y, Liu C and Tavassolian N (2021) An Open-Access Database for the Evaluation of Cardio-Mechanical Signals From Patients With Valvular Heart Diseases.<br> Front. Physiol. 12:750221. doi: 10.3389/fphys.2021.750221" when using this database.</p> <p>The archive comprises SCG and GCG recordings sourced from and processed at multiple sites worldwide, including Columbia University Medical Center and Stevens Institute of Technology in the USA, as well as Southeast University, Nanjing Medical University, and the first affiliated hospital of Nanjing Medical University in China. It includes electrocardiogram (ECG), SCG, and GCG recordings collected from 100 patients with various conditions of valvular heart diseases, such as aortic and mitral stenosis. The recordings were collected from clinical environments with the same types of wearable sensor patch. Besides the raw recordings of ECG, SCG and GCG signals, a set of hand-corrected fiducial point annotations is provided by manually checking the results of the annotated algorithm. The database also includes relevant echocardiogram parameters associated with each subject such as ejection fraction, valve area, and mean gradient pressure.</p>
Dataset: The role of social costs as a mechanism enforcing the honesty of ultraviolet-reflecting signals in a lizard
<p>Here are the data associated with the study entitled "The role of social costs as a mechanism enforcing the honesty of ultraviolet-reflecting signals in a lizard<strong>"</strong> authored by Anna Kawamoto, Jean-François Le Galliard, and Arnaud Badiane and published in <em>Biological Journal of the Linnean Society</em>.</p> <p>Four different data sets are provided and the Notes.xlsx file explains the content of these data sets.</p> <p>We also added three short videos showing typical lizards' behaviours scored in this study.</p> <p> </p>
Data set for manuscript 'A universal poroelastic mechanism for hydraulic signals in biomimetic and natural branches'
<p>The zip file contains all raw data associated with the manuscript 'A universal poroelastic mechanism for hydraulic signals in biomimetic and natural branches' with Python files used to process the data and plot the figures of the manuscript.</p>
Data from: Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex
<p>The brain predicts regularities in sensory inputs at multiple complexity levels, with neuronal mechanisms that remain elusive. Here, we monitored auditory cortex activity during the local-global paradigm, a protocol nesting different regularity levels in sound sequences. We observed that mice encode local predictions based on stimulus occurrence and stimulus transition probabilities, because auditory responses are boosted upon prediction violation. This boosting was due to both short-term adaptation and an adaptation-independent surprise mechanism resisting anesthesia. In parallel, and only in wakefulness, VIP interneurons responded to the omission of the locally expected sound repeat at sequence ending, thus providing a chunking signal potentially useful for establishing global sequence structure. When this global structure was violated, by either shortening the sequence or ending it with a locally expected but globally unexpected sound transition, activity slightly increased in VIP and PV neurons respectively. Hence, distinct cellular mechanisms predict different regularity levels in sound sequences.</p>
Data from: LAR1 activates NF-κB signaling pathway by binding to APOC1 mRNA and enhancing its expression: A novel mechanism underlying breast carcinogenesis
Open the record for dataset details and reuse information.
Data and code for Mechanisms of damage prevention, signalling, and repair impact the ability of Drosophila to tolerate enteric bacterial infection
<p>Data and code for</p> <p>Prakash, A., Monteith, K. M., & Vale, P. F. (2021). Mechanisms of damage prevention, signalling, and repair impact the ability of Drosophila to tolerate enteric bacterial infection. <em>bioRxiv</em>.</p> <p> </p> <p> </p>
Dataset for "A micro-opto-mechanical glass interferometer for megahertz modulation of optical signals"
<p>This dataset contains the raw data at the basis of the graphs reported in the paper:<br>"A micro-opto-mechanical glass interferometer for megahertz modulation of optical signals"<br>by Roberto Memeo, Andrea Crespi and Roberto Osellame.</p> <p>The preprint is uploaded in the arXiv.org repository: <br> arXiv:2402.01374 https://doi.org/10.48550/arXiv.2402.01374<br>This paper is published as:<br> Optica 11, 178-183 (2024). https://doi.org/10.1364/OPTICA.506669</p> <p>It contains one CSV file per graph. Figure numbering of the arXiv preprint is followed in naming the folders.</p>
Raw data for: Simulation of neurotrophin receptor transmembrane helix interactions reveals active states and distinct signaling mechanisms
<p>This repository contains raw data and code related to "Simulation of neurotrophin receptor transmembrane helix interactions reveals active states and distinct signaling mechanisms" by Athanasiou et al.</p> <p>Included are molecular dynamics parameter files, initial structures and structures shown in the figures of the manuscript.</p> <p> </p> <p>Contact information:</p> <p>Name: Rebecca C. Wade<br>Institution: Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS); Heidelberg, Germany<br>Email: Rebecca.wade@h-its.org</p> <p> </p> <p>This research was funded by the European Union’s Horizon 2020 research and innovation programme “Euroneurotrophin” under the Marie Skłodowska-Curie grant agreement No 765704 and the Klaus Tschira Foundation. </p>
Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data
<p>Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data</p>
Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data
<p>Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data</p>
Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling
<p><span>Biophysical cues of rigid tumor matrix play a critical role in cancer cell malignancy. Herein, we report that stiffly confined cancer cells exhibit robust growth of spheroids in the stiff hydrogel that exerts substantial confining stress on the cells. The stressed condition activated Hsp (heat shock protein)-STAT3 signaling via the TRPV4-PI3K/Akt axis, thereby upregulating the expression of the stemness-related markers in cancer cells, whereas these signaling activities were suppressed in cancer cells cultured in softer hydrogels or stiff hydrogels with stress relief or Hsp70 knockdown/inhibition. This mechanopriming based on 3D culture enhanced cancer cell tumorigenicity and metastasis in animal models upon transplantation, and pharmaceutically inhibiting Hsp70 improved the anticancer efficacy of chemotherapy. Mechanistically, our study reveals the crucial role of Hsp70 in regulating cancer cell malignancy under mechanically stressed conditions and its impacts on cancer prognosis-related molecular pathways for cancer treatments. </span></p>
White Blood Cell Signaling and Defense Mechanisms in Patients With Diabetes Mellitus Type 2 and Periodontitis
ClinicalTrials.gov study NCT01848379. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Signaling Mechanisms and Vascular Function in Patients With Diabetes Mellitus
ClinicalTrials.gov study NCT00762671. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling
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Data for "Molecular mechanism of biased signaling in a prototypical G protein–coupled receptor"
<p>Data and analysis code for "Molecular mechanism of biased signaling in a prototypical G protein–coupled receptor" (Suomivuori <em>et al.</em>, Science 367, 881–887 (2020)). See the included READMEs for more details. Please cite the paper if you use these data.</p>
Data from: What doesn't kill you makes you stronger: detoxification ability as mechanism of honesty in a sexually selected signal
<p>These files contain the data to perform all analysis done for the submitted manuscript <b>What doesn't kill you makes you stronger: detoxification ability as mechanism of honesty in a sexually selected signal.</b></p> <p> </p>
SP datasets for experimental study on the redox mechanism of geobattery and related electrical signals
<p><strong>The uploaded datasets are from the paper "Redox mechanism of geobattery and related electrical signals using a novel real-time self-potential monitoring experimental platform", which has been published at the <em>Journal of Central South University</em>. The laboratory data is available to all readers, and you can cite it by "Xie, J., Cui, Y., Zhang, L., et al. 2024. Redox mechanism of geobattery and related electrical signals using a novel real-time self-potential monitoring experimental platform. Journal of Central South University, 2024, 31(11): 1-19.".</strong></p> <p><strong>Note that there is a wrong description about the title of the journal paper in the "read me" file. Please ignore this issue. </strong></p> <p> </p>
Study on the Antidepressant Effects and Mechanism of Action of Cang-ai Volatile Oil Based on Near-Infrared Functional Brain Imaging and the NT-Trk Signalling Pathway
ClinicalTrials.gov study NCT07384312. IPD Sharing: NO. Countries: 1. Publications: 0.
Downstream Molecular Signals of P2Y12 Receptors in Hyporeactive Patients Under Clopidogrel Treatment A Possible Mechanism of HOTPR(High On-Treatment Platelet Reactivity)
ClinicalTrials.gov study NCT03190005. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: The return to water in ancestral Xenopus was accompanied by a novel mechanism for producing and shaping vocal signals
Open the record for dataset details and reuse information.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.