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38 results for “medicinal herbs”
An unexpected genetic diversity pattern and a complex demographic history of a rare medicinal herb, Chinese asparagus (Asparagus cochinchinensis) in Korea
Range-wide population studies of wide spread species are often associated with complex diversity patterns resulting from genetically divergent evolutionary significant units (ESUs). The compound evolutionary history creating such a pattern of diversity can be inferred through molecular analyses. Asparagus cochinchinensis, a medicinally important perennial herb, is in decline due to overharvesting in Korea. Eight A. cochinchinensis populations in Korea and three neighboring countries (China, Japan and Taiwan) were examined using nine nuclear microsatellite loci and three chloroplast microsatellite loci to characterize molecular diversity patterns. The average within-population diversity was limited likely due to long-term bottlenecks observed in all eight populations. High pairwise FST values indicated that the populations have largely diverged, but the divergences were not correlated with geographic distances. Clustering analyses revealed a highly complex spatial structure pattern associated with two ESUs. Approximate Bayesian Computation (ABC) suggest that the two ESUs split about 21,000 BP, were independently introduced to Korea approximately 1,800 years ago, and admixed in secondary contact zones. The two ESUs found in our study may have different habitat preferences and growth conditions, implying that the two genetically divergent groups should be considered not only for conservation and management but also for breeding programs in agricultural areas.
TCMID: Traditional Chinese Medicine integrative database for herb molecular mechanism analysis
<p><strong>ABSTRACT: </strong>Traditional Chinese Medicines Integrated Database and the description about Chinese herbs, including English and Latin names, properties, meridians, medicinal parts, herbal effect and indication. Traditional Chinese Medicine (TCM) is a system of healthcare and healing that has been practiced for thousands of years in China. It is based on a holistic approach that views the human body and its various systems as interconnected. TCM encompasses a wide range of practices, including herbal medicine, acupuncture, massage (tui na), exercise (qigong), and dietary therapy.</p> <p><strong>Instruction: </strong></p> <p>Data was cleaned and duplicates were removed.</p> <p><strong>Inspiration: </strong>The dataset was uploaded to UBRITE for "DGR_DEPOT" summer 2023 team project</p> <p><strong>Acknowledgements: </strong>Ruichao Xue 1, Zhao Fang, Meixia Zhang, Zhenghui Yi, Chengping Wen, Tieliu Shi</p> <p>TCMID: Traditional Chinese Medicine integrative database for herb molecular mechanism analysis. Nucleic Acids Res. 2013 Jan;41(Database issue):D1089-95. doi: 10.1093/nar/gks1100. Epub 2012 Nov 29. PMID: 23203875; PMCID: PMC3531123.</p> <p><strong>U-BRITE LAST UPDATED June 19, 2023</strong></p>
Fig. 7 in Preliminary investigations on the pathogenesis-related protein expression profile of the medicinal herb Macleaya cordata and anti-bacterial properties of recombinant proteins
Fig. 7. Antibacterial effects of a series of purified McDef1 concentration against S. aureus (A), E. coli (B), S. pullorum (C) and A. hydrophila (D). 1: 30 μg/ml, 2: 40 μg/ ml, 3: 50 μg/ml, 4: 60 μg/ml, 5: 80 μg/ml, 6: 100 μg/ml, 7: Negative control, empty vector expression supernatant; 8: Positive control, for A̢B̢C: 0.2 mg/mL Ampicillin, for D: 0.5 mg/mL Kanamycin.
Fig. 6 in Preliminary investigations on the pathogenesis-related protein expression profile of the medicinal herb Macleaya cordata and anti-bacterial properties of recombinant proteins
Fig. 6. Antibacterial effects of recombinant yeasts with McDef1 or McDef2 fermentation supernatant on S. aureus (A), S. pullorum (B), E. coli (C) and A. hydrophila (D). 1: Fermentation supernatant of the recombinant McDef1; 2: Fermentation supernatant of the recombinant McDef2; 3: Negative control, empty vector expression supernatant; 4: Positive control, A̢B̢C: 0.2 mg/mL Ampicillin; D: 0.5 mg/mL Kanamycin.
Fig. 4 in Preliminary investigations on the pathogenesis-related protein expression profile of the medicinal herb Macleaya cordata and anti-bacterial properties of recombinant proteins
Fig. 4. Multiple sequence alignments of the mature peptides of McLTP1 homologs from different plants with ClustalW2. The target proteins McLTP1 of this study are highlighted with yellow fluorescent background. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2 in Preliminary investigations on the pathogenesis-related protein expression profile of the medicinal herb Macleaya cordata and anti-bacterial properties of recombinant proteins
Fig. 2. Multiple sequence alignments of the McDef1 (A) and McDef2-5 (B) homologs from different plants with ClustalW2. The conserved domains α-core and γ-core are marked under the homologous sequences respectively. The target proteins McDef1 in (A) and McDef2-5 in (B) of this study are highlighted with yellow fluorescent background. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 1 in Preliminary investigations on the pathogenesis-related protein expression profile of the medicinal herb Macleaya cordata and anti-bacterial properties of recombinant proteins
Fig. 1. The alignment analysis of McDef1-5. The underlined amino acids represent the signal sequence predicted with SignalP. The cysteines are marked in yellow background and the putative disulfide bonds are also shown. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 8 in Preliminary investigations on the pathogenesis-related protein expression profile of the medicinal herb Macleaya cordata and anti-bacterial properties of recombinant proteins
Fig. 8. Antibacterial effects of a series of purified McDef2 concentration against S. aureus (A), E. coli (B), S. pullorum (C) and A. hydrophila (D). 1: 30 μg/ml, 2: 40 μg/ ml, 3: 50 μg/ml, 4: 60 μg/ml, 5: 80 μg/ml, 6: 100 μg/ml, 7: Negative control, empty vector expression supernatant; 8: Positive control, for A̢B̢C: 0.2 mg/mL Ampicillin, for D: 0.5 mg/mL Kanamycin.
Fig. 2 in Comparative transcriptome analysis infers bulb derived in vitro cultures as a promising source for sipeimine biosynthesis in Fritillaria cirrhosa D. Don (Liliaceae, syn. Fritillaria roylei Hook.) - High value Himalayan medicinal herb
Fig. 2. (A–E) Differential gene expression analysis in comparative F. roylei transcriptome: (A) Heat-map showing differential gene expression in the bulb (PKW) vs callus (PK2); bulb (PKW) vs in vitro regenerated plantlets (PK1) and callus (PK2) vs in vitro regenerated plantlets (PK1); (B) Venn diagram represents the differential gene expression in PKW vs PK1; PKW vs PK2; PK2 vs PK1, (C–E) Volcano plots represents the differential gene expression in PKW vs PK1; PKW vs PK2; PK2 vs PK1 as colour description image, where p-value & log2 fold-change in red colour represents genes with log2 fold-change cut off 2 and p-value <=0.05; p-value in blue colour represents genes with no cut off on log2 fold-change and p-value <=0.05. Whereas, log2 fold-change in green colour represents genes with fold-change cut off 2 but no p-value cut off and non-significant (NS) in grey colour represents genes with no filter on log2 fold-change and p-value, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 1 in Comparative transcriptome analysis infers bulb derived in vitro cultures as a promising source for sipeimine biosynthesis in Fritillaria cirrhosa D. Don (Liliaceae, syn. Fritillaria roylei Hook.) - High value Himalayan medicinal herb
Fig. 1. (A–F) Functional annotations and unigenes classification of comparative F. roylei transcriptome: (A) Unigenes annotation with top 15 different plant species; (B) Top 5 pathway representation as per Kyoto Encyclopedia of Genes and Genomes; (C) Gene Ontology classification under the cellular component, molecular function, and biological process categories; (D) COG (Cluster of Orthologous Groups of proteins) classification into nine different categories; (E) Unigenes classification into major transcription factor families; (F) Gene family and sub-family classification using TAIR database.
Fig. 4 in Comparative transcriptome analysis infers bulb derived in vitro cultures as a promising source for sipeimine biosynthesis in Fritillaria cirrhosa D. Don (Liliaceae, syn. Fritillaria roylei Hook.) - High value Himalayan medicinal herb
Fig. 4. Comparative expression pattern validation for the sipeimine biosynthetic pathway genes as obtained from RNA-Seq data and qRT-PCR.
Fig. 3 in Comparative transcriptome analysis infers bulb derived in vitro cultures as a promising source for sipeimine biosynthesis in Fritillaria cirrhosa D. Don (Liliaceae, syn. Fritillaria roylei Hook.) - High value Himalayan medicinal herb
Fig. 3. Proposed sipeimine biosynthetic pathways in F. roylei. Heat-map showing gene expression in the bulb, callus, and regenerated plantlets. The genes were mapped using TPM (transcripts per kilobase million) values and colour-coded by increasing relative expression. The broken dotted arrow represents putative terminal biosynthesis steps. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Chinese Medicinal Herbs Treatment on Novel Influenza A (H1N1) : Multi-centre, Prospective, Randomized Controlled Study
ClinicalTrials.gov study NCT00935194. IPD Sharing: Not stated. Countries: 1. Publications: 1.
An unexpected genetic diversity pattern and a complex demographic history of a rare medicinal herb, Chinese asparagus (Asparagus cochinchinensis) in Korea
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Figure 1 from: Proskurina K, Yevtifieieva O, Mala O, Mashtaler V (2021) Development of the method for standardization of the medicinal plant raw material of Cichorium intybus L. herb by the total amount of hydroxycinnamic acid derivatives. Pharmacia 68(1): 167-173. https://doi.org/10.3897/pharmacia.68.e49273
Figure 1 The TLC chromatogram of hydroxycinnamic acids in ethanolic extracts of different samples of chicory herb originating from Ukraine. S1–3: chlorogenic acid, caffeic acid and ferulic acid as references; for plant extracts, see abbreviations in Table 3.
Figure 2 from: Proskurina K, Yevtifieieva O, Mala O, Mashtaler V (2021) Development of the method for standardization of the medicinal plant raw material of Cichorium intybus L. herb by the total amount of hydroxycinnamic acid derivatives. Pharmacia 68(1): 167-173. https://doi.org/10.3897/pharmacia.68.e49273
Figure 2 The absorption spectrum of ethanol (50 per cent V/V) chicory herb extracts for 8 sample of the raw plant material. See abbreviations in Table 3. UV/Vis absorption spectra of chlorogenic acid chemical standard at 10.08 µg/ml in ethanol (50 per cent V/V).
Figure 3 from: Proskurina K, Yevtifieieva O, Mala O, Mashtaler V (2021) Development of the method for standardization of the medicinal plant raw material of Cichorium intybus L. herb by the total amount of hydroxycinnamic acid derivatives. Pharmacia 68(1): 167-173. https://doi.org/10.3897/pharmacia.68.e49273
Figure 3 Absorbance values of chlorogenic acid as a function of the solution concentrations. The data correlation was calculated by a linear fit.
Survey data of Chinese medicinal herb farmers
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Characterization of the complete chloroplast genome of the medicinal herb Veronica polita Fr. (Lamiales: Plantaginaceae)
<p><em>Veronica polita</em> Fr. (synonym: <em>Veronica didyma</em> Ten.), an annual herbaceous species with high medicinal values, is originally from Southwest Asia but has been naturalized widely in many regions of the world. In this study, the complete chloroplast genome of <em>V. polita</em> was determined to be 150,191 bp long with a typical quadripartite structure. It encodes a panel of 114 genes with 18 of them being completely or partially duplicated and 19 of them possessing one or two introns. The phylogenetic analysis appeared to support the tribal-level taxonomy of the family Plantaginaceae, and revealed that <em>V. polita</em> was most closely related to the congener <em>V. persica</em>.</p>
Fig. 4 in Ethnobotanical survey of culinary herbs and spices used in the traditional medicinal system of Nkonkobe Municipality, Eastern Cape, South Africa
Fig. 4. Traditional methods of preparation of spices for medicinal use.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.