Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
18
datasets available to search
ShareScore release 0.9.0
Dataset results
18 results for “membrane repair”
Data from: Triggered Golgi membrane enrichment promotes PtdIns(4,5)P2 generation for plasma membrane repair
<p><span>The maintenance of plasma membrane integrity and a capacity for efficiently repairing damaged membranes are essential for cell survival. Large-scale wounding depletes various membrane components at the wound sites, including phosphatidylinositols, yet little is known about how phosphatidylinositols are generated after depletion. Here, working with our <em>in</em> <em>vivo C. elegans</em> epidermal cell wounding model, we discovered phosphatidylinositol 4-phosphate (PtdIns4<em>P</em>) accumulation and local phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)<em>P<sub>2</sub></em>] generation at the wound site. We found that PtdIns(4,5)<em>P<sub>2</sub></em> generation depends on the delivery of PtdIns4<em>P</em>, PI4K, and PI4P 5-kinase PPK-1. In addition, we show that wounding triggers enrichment of the Golgi membrane to the wound site, and that is required for membrane repair. Moreover, genetic and pharmacological inhibitor experiments support that the Golgi membrane provides the PtdIns4<em>P</em> for PtdIns(4,5)<em>P<sub>2</sub></em> generation at the wounds. Our findings demonstrate how the Golgi apparatus facilitates membrane repair in response to wounding and offers a valuable perspective on cellular survival mechanisms upon mechanical stress in a physiological context. </span></p>
Data from: Triggered Golgi membrane enrichment promotes PtdIns(4,5)P2 generation for plasma membrane repair
Open the record for dataset details and reuse information.
Mechanism for Vipp1 spiral formation, ring biogenesis and membrane repair
<p><span><span>Here</span><span>,</span><span> we collect </span><span>an image dat</span><span>aset</span><span> of Vipp1 polymerization dynamics on supported lipid bilayers </span><span>using atomic force microscopy (</span><span>AFM</span><span>)</span><span>. A JPK </span><span>NanoWizard</span> <span>Ultraspeed</span><span> AFM (Bruker and JPK </span><span>BioAFM</span><span>) equipped with USC-F0.3-k0.3-10 cantilevers with spring constant of 0.3N nm−1, resonance frequency of about 300 kHz (Nanoworld), was </span><span>employed </span><span>for image acquisition. The AFM was </span><span>operated</span><span> in tapping mode</span><span> with a</span><span> cantilever </span><span>oscil</span><span>l</span><span>ation </span><span>frequency </span><span>near </span><span>to 150kHz. </span><span>Both</span><span> topographic and phase images </span><span>were analysed </span><span>using</span><span> JPKSPM Data Processing, ImageJ, and </span><span>WSxM</span><span> software</span></span>.</p>
In-office Repair of Chronic Tympanic Membrane Perforations
ClinicalTrials.gov study NCT06448039. IPD Sharing: NO. Countries: 1. Publications: 3.
Mensenchymal Stem Cell (MSC) Included in OrthADAPT Membrane for Rotator Cuff Tears Repair
ClinicalTrials.gov study NCT01687777. IPD Sharing: Not stated. Countries: 1. Publications: 26.
Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique
ClinicalTrials.gov study NCT02256891. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Post-market Clinical Investigation Plan: Collagen Dura Regeneration Membrane - Repair (DMR)
ClinicalTrials.gov study NCT07371091. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Sticky Bone Grafting With Concentrated Growth Factor Membrane for Repair of Unilateral Alveolar Cleft
ClinicalTrials.gov study NCT07066293. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effect of Human Amniotic Membrane Allograft on Functional Recovery After Flexor Tendon Repair
ClinicalTrials.gov study NCT02361814. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Perf-Fix Study for Chronic Tympanic Membrane Repair
ClinicalTrials.gov study NCT06083181. IPD Sharing: NO. Countries: 1. Publications: 0.
Surgical Repair of Vaginal Wall Prolapse Using Gamma Irradiated Amniotic Membrane as a Scaffold
ClinicalTrials.gov study NCT05355623. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Chondro-Gide® Bilayer Collagen Membrane in Knee Cartilage Defect Repair
ClinicalTrials.gov study NCT05785949. IPD Sharing: NO. Countries: 1. Publications: 0.
A Clinical Study on the Efficacy and Safety of Lando® Absorbable Collagen Membrane in Oral Bone Repair
ClinicalTrials.gov study NCT03464786. IPD Sharing: NO. Countries: 1. Publications: 0.
Mesenchymal Stem Cells and Amniotic Membrane Composite for Supraspinatus Tendon Repair Augmentation
ClinicalTrials.gov study NCT04670302. IPD Sharing: Not stated. Countries: 1. Publications: 0.
LITAF PROMOTES MEMBRANE REPAIR AGAINST PORE-FORMING PROTEINS
GEO Series GSE242913. Homo sapiens. 34 samples. Type: Other.
USP8 coordinates ESCRT-mediated membrane repair, xenophagy, and oxidative stress responses during Mycobacterium tuberculosis infection
GEO Series GSE240372. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
Repair of Tympanic Membrane Perforation Using Tachosil Under Local Anesthesia
ClinicalTrials.gov study NCT04428463. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Assessment of Collagen Membrane Interest in Distal Cuff Lesions Repair
ClinicalTrials.gov study NCT06269965. IPD Sharing: NO. Countries: 0. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.