Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
19
datasets available to search
ShareScore release 0.9.0
Dataset results
19 results for “microcystin”
The effects the mode of delivery of microcystin-LR has on rusty crayfish (Faxonius rusticus) behavior and physiology
Microcystin is a deadly toxin produced during algal blooms. The cells release MCLR which can cause significant neurological and behavioral damage to organisms exposed to the toxin. MCLR can exist in the water column and in the sediment and through normal ecological processes move between those two states or location. Given the location of the toxin, it is possible that MCLR in the sediment could have different adverse effects on organisms as opposed to when the toxin is in the water column. We tested that idea using crayfish that were exposed to either nothing, a vehicle to carry the mclr, and mclr. In addition, the toxin and vehicle were dosed either in the water column or in the sediment. Behavioral and physiological measures were taken after 4 days of exposure, The results indicate that at both the behavioral and physiological level, the location of the toxin has different adverse effects.
Microcystin-LR (one of the toxic congeners of microcystin) exposure causes crayfish to forget previous fight outcomes as well as previous opponents, MI, 2025
Harmful algal blooms are increasing across the globe as a function of nutrient run off and climate change. While the study of the mechanisms that underlie the blooms themselves are abundant, the impact of the toxins produced by blooms needs more research. Crayfish are keystone species in aquatic habitats and rely on chemoreception for many of their ecosystem functions. Crayfish were placed in a fight arena for measure both the outcome and dynamics aspects of agonistic encounters. Then the loser of the fights were exposed to either controls or microcystin for four days. Afterwards, the crayfish fought either another unfamiliar opponent or the previous opponent. The data contained in this package has the concentrations of microcystin exposure, morphological data on the crayfish, and then behavioral data from the two different fights. The behavioral data has two categories: time spent at different levels of intensity and time it took the crayfish pair to reach a certain intensity.
S85 | MICROCYSTINS | Microcystins from CyanoMetDB
<p>This is the collection associated with list S75 CyanoMetDB Comprehensive database of secondary metabolites from cyanobacteria on the NORMAN Suspect List Exchange.</p> <p><a href="https://www.norman-network.com/nds/SLE/">https://www.norman-network.com/nds/SLE/</a></p> <p>Over 300 microcystins extracted from CyanoMetDB (latest version), most of natural origin. <br> This completes the draft version of S83 EPA CCL5 wherein Cyanotoxin "Microcystin".<br> Another list with 7 entries under same name (singular) exists (https://comptox.epa.gov/dashboard/chemical_lists/MICROCYSTIN)</p> <p>All fields provided by Lilli from CyanoMetDB retained* except for following changes</p> <ul> <li> DTXSIDs updated via comptox search using InChIKeys.</li> <li> Missing PubChem IDs updated using PubChem identifier exchange </li> <li> "PREFERRED NAMES" obtained added as additional synonyms column</li> </ul>
Semi-quantitative microcystin concentration measured in surface water samples collected by the Citizen-Led Environmental Observatory (CLEO) from multiple nearshore sites in Lake Lillinonah, Connecticut, USA, 2015-2018
Included in this data package are cyanobacterial toxin data from the Citizen-Led Environmental Observatory (CLEO), a volunteer water quality monitoring program run by Friends of the Lake (FOTL, friendsofthelake.org) and Fairfield University at Lake Lillinonah, Connecticut, USA. The program has been operational since 2008 (toxin data available form 2015-2018). Trained volunteer monitors collect routine surface water samples from multiple nearshore sites twice a month from Memorial Day through Labor Day. In addition, spot samples are taken whenever a significant algae bloom is present at the collection site. These samples are analyzed for microcystin concentrations. Routine water samples are also analyzed for levels of the total nitrogen and phosphorus concentrations. Additionally, CLEO volunteers collect data on water temperature, Secchi disk depth, water color, presence of floating woody debris, recreation potential, trash, particle type and surface scum every 1-3 days during the same period. These data are available in EDI packages EDI567 (general water quality) and EDI568 (nutrients).
Data from: Microcystins bioaccumulate but do not biomagnify in an experimental aquatic food chain
Open the record for dataset details and reuse information.
Microcystin production by Nostoc in Greenlandic lakes
<p>Benthic primary producers are recognized for their important role in contributing to ecosystem productivity and nutrient cycling in lake and stream ecosystems, particularly in polar environments. In Arctic lakes, benthic producers often comprise mats or colonies of cyanobacteria capable of producing cyanotoxins. However, the extent to which benthic communities contribute cyanotoxins in polar regions remains poorly described. We evaluated the potential for benthic colonies of the cyanobacterium <i>Nostoc pruniforme </i>from lakes in Kangerlussuaq, Greenland, to contribute microcystins (MCs) to lake water using three approaches. First, we dissected field-collected <i>Nostoc </i>colonies and measured MCs within multiple layers of fresh colony tissue. Second, we conducted a laboratory experiment to evaluate the temporal dynamics of MC release by incubated, intact colonies. Finally, we quantified whether MC concentrations in water and sediment samples in the field were higher in and above dense bands of benthic <i>Nostoc </i>as compared to bare sediment. Field-collected <i>Nostoc </i>colonies contained MCs throughout the colony tissue, suggesting that damage to colonies from grazers or physical disturbance could facilitate the release of toxins into the water. Undamaged <i>Nostoc </i>colonies incubated in high-nutrient conditions in the laboratory leaked MCs into the surrounding water at a steady mass-specific rate over the course of seven days. MC concentrations in water and sediment from two Greenlandic lakes were highly variable, but slightly higher in lake water immediately above dense bands of <i>Nostoc </i>than in water immediately above bare sediments, suggesting that benthic <i>Nostoc </i>colonies contribute cyanotoxins to lake water and that MCs vary at very fine, 1-2 m spatial scales. Benthic cyanobacteria may be important in releasing MCs into aquatic ecosystems, especially in systems where benthic producers dominate, such as polar environments.</p>
Microcystin production by Nostoc in Greenlandic lakes
Open the record for dataset details and reuse information.
Meta-analysis data for Microcystin as a Biogeochemical Cycle: pools, fluxes, and fates of the cyanotoxin in inland waters
We constructed a conceptual biogeochemical model for microcystin through a comprehensive literature synthesis, identifying four major pools and nine major fluxes in lakes that also connect to the terrestrial environment. We also performed a literature synthesis, collating measurements of various pools and fluxes of microcystin in inland waters from the literature. A subset of those values were used in an analysis of microcystin detection for field surveys of waterbodies and a random effects model to estimate the mean and 95% confidence interval for various microcystin pools and fluxes in lakes.
Global transcriptomic profiling of microcystin-LR or -RR treated hepatocytes (HepaRG)
GEO Series GSE147999. Homo sapiens. 148 samples. Type: Expression profiling by high throughput sequencing.
Differentially expressed genes in the livers of mice exposed to microcystin-LR (MC-LR)
GEO Series GSE145459. Mus musculus. 6 samples. Type: Expression profiling by array.
Alteration of MicroRNA Expression Profile Linked to Microcystin-LR-Induced Tumorigenicity in Human WRL-68 Cell Line
GEO Series GSE30560. Rattus norvegicus; JC polyomavirus; Betapolyomavirus hominis; Murid gammaherpesvirus 4; Human gammaherpesvirus 8; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; human gammaherpesvirus 4; Betapolyomavirus macacae. 2 samples. Type: Non-coding RNA profiling by array.
Microcystin-LR prenatal exposure induces coronary heart disease through macrophage polarization imbalance mediated by trophoblast-derived extracellular vesicles.
GEO Series GSE266672. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Analysis of MicroRNA Expression in Embryonic Developmental Toxicity Induced by microcystin arginine arginine (MC-RR).
GEO Series GSE29329. Danio rerio. 8 samples. Type: Non-coding RNA profiling by array.
Expression data from 20-day-old mouse Sertoli cells and 20-day-old Sertoli cell treated with 500 nm Microcystin-Leucine Arginine (MC-LR)
GEO Series GSE87475. Mus musculus. 2 samples. Type: Expression profiling by array.
Transcriptional and Behavioral Responses of Zebrafish Larvae to Microcystin-LR Exposure
GEO Series GSE73739. Danio rerio. 6 samples. Type: Expression profiling by array.
Microcystin Genomic Effects on Zebrafish Larvae
GEO Series GSE12214. Danio rerio. 15 samples. Type: Expression profiling by array.
Transcriptome analysis of Novosphingobium sp. THN1 during microcystin-LR degradation under different carbon concentrations
GEO Series GSE125827. Novosphingobium sp. THN1. 9 samples. Type: Expression profiling by high throughput sequencing.
Microarray Analysis of Microcystin-LR
GEO Series GSE59495. Rattus norvegicus. 90 samples. Type: Expression profiling by array.
Harmful algal bloom toxin microcystin-LR interferes with PP1-mediated PI3K/AKT/FOXO1 signaling in granulosa cells to disrupt ovarian follicle maturation and ovulation
GEO Series GSE201806. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.