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15 results for “mobile DNA”
Distinct mobility patterns of BRCA2 molecules at DNA damage sites - source data
<p>This repository contains source data from the publication "Distinct mobility patterns of BRCA2 molecules at DNA damage sites"</p><p>- Source data of FRAP experiments. Text files contain time and intensity data of the individual FRAP curves including the normalized intensities as plotted in the figure.</p><p>- Source data for BRCA2 protein quantification </p><p>- dSTORM localization data</p><p>- Single-molecule tracks of BRCA2-Halo Mitomycin and untreated tracks. Original movies can be found here: http://doi.orig/10.5281/zenodo.10144073</p><p>For questions please contact Maarten Paul (m.w.paul [at] erasmusmc.nl</p>
Distinct mobility patterns of BRCA2 molecules at DNA damage sites v2
<p>This repository contains source data and processed data accompanied with the paper:</p><p>"Distinct mobility patterns of BRCA2 molecules at DNA damage sites"</p><p>The repository contains the following files:</p><p>single molecule tracking data of BRCA2-HaloTag (JF549) in mouse ES cells either untreated or Mitomycin C (MMC) treated cells. For details on the experimental conditions please check the methods section of the accompanying paper.</p><p>At http://doi.org/10.5281/zenodo.8143173 the corresponding tracking data can be found, among other source data of this study.</p><p>For questions please contact Maarten Paul (m.w.paul [at] erasmusmc.nl</p>
HPV DNA Testing Through Mobile Mammography Unit
ClinicalTrials.gov study NCT03551028. IPD Sharing: NO. Countries: 1. Publications: 2.
Autologous DNA mobilization and multiplication expedite natural products discovery from bacteria
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Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby
<p>DNA mismatch repair (MMR), the guardian of the genome, commences when MutS identifies a mismatch and recruits MutL to nick the error-containing strand, allowing excision and DNA resynthesis. Dominant MMR models posit that after mismatch recognition, ATP converts MutS to a hydrolysis-independent, diffusive mobile clamp that no longer recognizes the mismatch. Little is known about the postrecognition MutS mobile clamp and its interactions with MutL. Two disparate frameworks have been proposed: One in which MutS–MutL complexes remain mobile on the DNA, and one in which MutL stops MutS movement. Here we use single-molecule FRET to follow the postrecognition states of MutS and the impact of MutL on its properties. In contrast to current thinking, we find that after the initial mobile clamp formation event, MutS undergoes frequent cycles of mismatch rebinding and mobile clamp reformation without releasing DNA. Notably, ATP hydrolysis is required to alter the conformation of MutS such that it can recognize the mismatch again instead of bypassing it; thus, ATP hydrolysis licenses the MutS mobile clamp to rebind the mismatch. Moreover, interaction with MutL can both trap MutS at the mismatch en route to mobile clamp formation and stop movement of the mobile clamp on DNA. MutS's frequent rebinding of the mismatch, which increases its residence time in the vicinity of the mismatch, coupled with MutL's ability to trap MutS, should increase the probability that MutS–MutL MMR initiation complexes localize near the mismatch.</p> <p> </p>
Data from: Assessing the spatial ecology and resource use of a mobile and endangered species in an urbanized landscape using satellite telemetry and DNA faecal metabarcoding
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Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby
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Data from: A mobile laboratory for ancient DNA analysis
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High Mobility Group protein mediated transcription requires DNA damage marker γ-H2AX
GEO Series GSE63861. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A map of mobile DNA insertions in the NCI-60 human cancer cell panel
GEO Series GSE83756. Homo sapiens. 60 samples. Type: Genome variation profiling by genome tiling array.
High Mobility Group Box protein 3 (HMGB3) facilitates DNA interstrand crosslink processing and double-strand break repair in human cells
GEO Series GSE285696. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription
GEO Series GSE124769. Homo sapiens. 49 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Genome-wide DNA methylation identifies trophoblast invasion-related genes: Claudin-4 and Fucosyltransferase IV control mobility via altering matrix metalloproteinase activity
GEO Series GSE60885. Homo sapiens. 17 samples. Type: Methylation profiling by genome tiling array.
Plant Mobile Domain protein-DNA motif modules counteract Polycomb silencing to stabilize gene expression
GEO Series GSE278560. Arabidopsis thaliana. 100 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
DNA damage-induced HSPC failure depends on ROS accumulation downstream of IFN-1 signaling and Bid mobilization
GEO Series GSE85076. Mus musculus. 12 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.