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Dataset results
28 results for “motor skill learning”
Dataset for the Article entitled "Dissociable effects of practice variability on learning motor and timing skills"
<p>Dataset collected for studying the effect of the amount and the schedule of task variability on motor and timing learning.</p>
Neural ensemble reactivation in REM and SWS coordinate with muscle activity to promote rapid motor skill learning
<p>Neural activity patterns of recent experiences are reactivated during sleep in structures critical for memory storage, including hippocampus and neocortex. This reactivation process is thought to aid memory consolidation. Although synaptic rearrangement dynamics following learning involve an interplay between slow-wave sleep (SWS) and rapid eye movement sleep (REM), most physiological evidence implicates SWS directly following experience as a preferred window for reactivation. Here we show that reactivation occurs in both REM and SWS, and that coordination of REM and SWS activation on the same day is associated with rapid learning of a motor skill. We performed 6-hour recordings from cells in rats' motor cortex as they were trained daily on a skilled reaching task. In addition to SWS following training, reactivation occurred in REM, primarily during the pre-task rest period, and REM and SWS reactivation occurred on the same day in rats that acquired the skill rapidly. Both pre-task REM and posttask SWS activation were coordinated with muscle activity during sleep, suggesting a functional role for reactivation in skill learning. Our results provide the first demonstration that reactivation in REM sleep occurs during motor skill learning, and that coordinated reactivation in both sleep states on the same day, although at different times, is beneficial for skill learning.</p>
Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex
<p>Cholecystokinin (CCK) is an essential modulator for neuroplasticity in sensory and emotional domains. Here, we investigated the role of CCK in motor learning using a single pellet reaching task in mice. Mice with a knockout of <em>cck</em> gene (CCK<sup>-/-</sup>) or blockade of CCK-B receptor (CCKBR) showed defective motor learning ability; the success rate of retrieving reward remained at the baseline level compared to the wildtype mice with significantly increased success rate. We observed no long-term potentiation (LTP) upon high-frequency stimulation (HFS) in the motor cortex of CCK<sup>-/-</sup> mice, indicating a possible association between motor learning deficiency and neuronal plasticity in the motor cortex. In vivo calcium imaging demonstrated that the deficiency of CCK signalling disrupted the refinement of population neuronal activity in the motor cortex during motor skill training. Anatomical tracing revealed direct projections from CCK-expressing neurons in the rhinal cortex to the motor cortex. Inactivating the CCK neurons in the rhinal cortex using chemogenetic methods significantly suppressed motor learning, and intraperitoneal application of CCK4, a tetrapeptide CCK agonist, rescued the motor learning deficits of CCK<sup>-/-</sup> mice. In summary, our results suggest that CCK, which could be provided from the rhinal cortex, enables neuroplasticity in the motor cortex leading to motor skill learning.</p>
Neural ensemble reactivation in REM and SWS coordinate with muscle activity to promote rapid motor skill learning
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Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex
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Data for paper "Information flow between motor cortex and striatum reverses during skill learning"
<p>Simultaneous spiking activity and local field potential (LFP) recordings from motor cortex (M1) and dorsolateral striatum (DLS) during learning of a reach-to grasp task.<br>Deposited data include spiking activity and LFP recordings, reaching trajectories, andi single-trial success data for the 8 animals included in the paper "Information flow between motor cortex and striatum reverses during skill learning".</p>
Bimanual Motor Skill Learning Through Robotics in Chronic Cerebellar Stroke Survivors and Healthy Individuals
ClinicalTrials.gov study NCT04642599. IPD Sharing: YES. Countries: 1. Publications: 4.
Influence of G-CSF and EPO on Associative Learning and Motor Skills
ClinicalTrials.gov study NCT00298597. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Facilitating Motor Skill Learning in Parkinson's Disease
ClinicalTrials.gov study NCT03245216. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Implementation of a New Motor Skill Learning Therapeutic Device in Children With Cerebral Palsy Rehabilitation
ClinicalTrials.gov study NCT03930836. IPD Sharing: NO. Countries: 1. Publications: 1.
Self-Adaptive Immersive Virtual Reality Serious Game to Enhance Motor Skill Learning and Attention in Older Adults
ClinicalTrials.gov study NCT06141642. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Investigating How Sleep After Training Can Affect the Learning of a Motor Skill in Individuals With Brain Injury
ClinicalTrials.gov study NCT04810442. IPD Sharing: NO. Countries: 1. Publications: 15.
Bimanual Motor Skill Learning Through Robotics in Stroke Survivors and Healthy Individuals
ClinicalTrials.gov study NCT03974750. IPD Sharing: YES. Countries: 1. Publications: 5.
Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis
ClinicalTrials.gov study NCT06919900. IPD Sharing: NO. Countries: 1. Publications: 3.
Consolidation of Motor Learning of Writing Skills and Its Related Brain Activity Changes in Parkinson's Disease
ClinicalTrials.gov study NCT02288052. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data from: Coupling between motor cortex and striatum increases during sleep over long-term skill learning
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Motor Skill Learning in People With Parkinson's Disease
ClinicalTrials.gov study NCT00396942. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Spinal Reflexes in Motor Skill Learning
ClinicalTrials.gov study NCT00076583. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Frontal and Parietal Contributions to Proprioception and Motor Skill Learning
ClinicalTrials.gov study NCT05739994. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Does the Continuous Repetition of Motor Skills at a Consistent Speed With Music Affect Children's Decision-Making and Learning Abilities?
ClinicalTrials.gov study NCT07147686. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.