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69 results for “muscle contraction”
Surface EMG recordings of the biceps brachii muscle during voluntary isometric contractions - pilot study on fatigue
<p>This publication contains the data recorded during a study on muscle fatigue and its evaluation using surface electromyography (EMG). There were a total of 16 participants. Each directory, with an alphanumeric value contains data from a single participant (.mat and .json files). The README.pdf file in the root directory provides details on the experimental set-up and protocol, and data in each file. </p> <p>The EMG data are provided in matlab files and in addition to those, there are recordings of the <a href="https://doi.org/10.1016/j.jelekin.2019.05.012">perceived fatigue of the participants using a modified Borg CR-10 scale</a> in the json file, in which further participant and experimental information are provided.<br>For each participant information on gender, age (in aggregate form) and height (in aggregate form) are provided.</p> <p> </p>
Combined Application of Electrical Stimulation and Volitional Contractions for Muscle Strengthening and Knee Pain Inhibition (Seated Study)
ClinicalTrials.gov study NCT02802878. IPD Sharing: NO. Countries: 1. Publications: 36.
Myosin cross-bridge kinetics slow at longer muscle lengths during isometric contractions in intact soleus from mice
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Locomotor resilience through load-dependent modulation of muscle co-contraction
<p>Terrestrial locomotor behavior in variable environments requires resilience to sudden changes in substrate properties. For example, walking animals can adjust to substantial changes in slope and corresponding changes in load distribution among legs. In insects, slope-dependent adjustments have mainly been examined under steady-state conditions, whereas the transition dynamics have been largely neglected. In a previous study, we showed that steady-state adjustments of stick insects to ±45° slopes involve substantial changes in joint torques and muscle activity with only minor changes in leg kinematics. Here, we take a close look at the time course of these adjustments as stick insects compensate for various kinds of disturbances to load distribution. In particular, we test whether the transition from one steady state to another involves distinct transition steps or follows a graded process. To resolve this, we combined simultaneous recordings of whole-body kinematics and hind leg muscle activity to elucidate how freely walking <em>Carausius morosus</em> negotiated a step-change in substrate slope. Step-by-step adjustments reveal that muscle activity changed in a graded manner as a function of body pitch relative to gravity. We further show analogous transient adjustment of muscle activity in response to destabilizing lift-off events of neighboring legs and the disappearance of antagonist co-activation during crawling episodes. Given these three examples of load-dependent regulation of antagonist muscle co-contraction, we conclude that stick insects respond to both transient and sustained changes in load distribution by regulating joint stiffness rather than through distinct transition steps.</p>
The role of action potential changes in depolarization-induced failure of excitation contraction coupling in mouse skeletal muscle
<p>Excitation-contraction coupling (ECC) is the process by which electrical excitation of muscle is converted into force generation. Depolarization of skeletal muscle resting potential contributes to failure of ECC in diseases such as periodic paralysis, intensive care unit acquired weakness and possibly fatigue of muscle during vigorous exercise. When extracellular K<sup>+</sup> is raised to depolarize the resting potential, failure of ECC occurs suddenly, over a narrow range of resting potentials. Intracellular recordings of action potentials (APs) in individual mouse skeletal muscle fibers during depolarization of the resting potential revealed small APs are still generated at resting potentials at which force production has failed. Simultaneous imaging of Ca<sup>2+ </sup>transients and recording of APs demonstrated failure to generate Ca<sup>2+ </sup>transients when APs peaked at potentials more negative than -30 mV. An AP property that closely correlated with failure of the Ca<sup>2+</sup> transient was the integral of AP voltage with respect to time. Simultaneous recording of Ca<sup>2+ </sup>transients and APs with electrodes separated by 1.6 mm revealed AP conduction fails when APs peak below -21 mV. We hypothesize propagation of APs and generation of Ca<sup>2+</sup> transients are governed by distinct AP properties: AP conduction is governed by AP peak, whereas Ca<sup>2+</sup> release from the sarcoplasmic reticulum is governed by AP integral of voltage with respect to time. The reason distinct AP properties may govern separate steps of ECC is the kinetics of the ion channels involved in the different steps of ECC. Na channels, which govern propagation, have rapid kinetics such that propagation is insensitive to AP width (and integral) whereas Ca<sup>2+</sup> release is governed by movement of gating charges in Cav1.1 channels, which have slower kinetics such that Ca<sup>2+ </sup>release is sensitive to AP width (and integral). The quantitative relationships established between resting potential, AP properties, AP conduction and Ca<sup>2+</sup> transients provide the foundation for future studies of failure of ECC induced by depolarization of the resting potential.</p>
Effect of the Different Methods of Kinesiology Taping on the Muscle Contraction Performance of Fatigued Biceps Brachii
ClinicalTrials.gov study NCT04487184. IPD Sharing: NO. Countries: 1. Publications: 1.
Verbal Instruction for Contraction Pelvic Floor Muscles Among Males
ClinicalTrials.gov study NCT03507660. IPD Sharing: YES. Countries: 1. Publications: 1.
Pelvic Floor Muscle Contraction Among Physiotherapy Students Before and After "Women Health" Course
ClinicalTrials.gov study NCT03917615. IPD Sharing: YES. Countries: 1. Publications: 1.
Can Women Correctly Contract Their Pelvic Floor Muscles After to Receive Verbal Instructions and Vaginal Palpation?
ClinicalTrials.gov study NCT03325543. IPD Sharing: NO. Countries: 1. Publications: 1.
Pelvic Floor Muscle Contraction in Response to Different Verbal Instructions in Women With Urinary Incontinence
ClinicalTrials.gov study NCT03940794. IPD Sharing: NO. Countries: 1. Publications: 3.
What is the Best Verbal Instruction for Contraction the Pelvic Floor Muscles?
ClinicalTrials.gov study NCT03400540. IPD Sharing: YES. Countries: 1. Publications: 2.
Effect of Verbal Instruction on Pelvic Floor Muscle Contraction in Post Stroke Patients
ClinicalTrials.gov study NCT03903627. IPD Sharing: YES. Countries: 1. Publications: 3.
Effectiveness of Abdomino-pelvic Muscle Contraction Education Programme in Healthy Male University Students
ClinicalTrials.gov study NCT06786182. IPD Sharing: NO. Countries: 1. Publications: 4.
Effect of Post Isometric Relaxation Technique & Eccentric Muscle Contraction on Hamstring Spasticity in CP
ClinicalTrials.gov study NCT03708757. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Locomotor resilience through load-dependent modulation of muscle co-contraction
Open the record for dataset details and reuse information.
The role of action potential changes in depolarization-induced failure of excitation contraction coupling in mouse skeletal muscle
Open the record for dataset details and reuse information.
Data from: Fatiguing effects of indirect vibration stimulation in upper limb muscles- post and during isometric contractions superimposed on upper limb vibration
Whole body vibration and upper limb vibration (ULV), continues to gain popularity as exercise intervention for rehabilitation and sports applications. However, the fatiguing effects of indirect vibration stimulation are not yet fully understood. We investigated the effects of ULV stimulation superimposed on fatiguing isometric contractions using a purpose developed upper limb stimulation device. Thirteen healthy volunteers were exposed to both ULV superimposed to fatiguing isometric contractions (V) and isometric contractions alone- Control (C). Both Vibration (V) and Control (C) exercises were performed at 80% of the maximum voluntary contractions. The stimulation used was 30 Hz frequency of 0.4 mm amplitude. Surface-electromyographic (EMG) activity of the Biceps Brachii, Triceps Brachii, and Flexor Carpi Radialis were measured. EMG amplitude (EMGrms) and mean frequency (MEF) were computed to quantify muscle activity and fatigue levels. All muscles displayed significantly higher reduction in MEFs and corresponding significant increase in EMGrms with the V than the Control, during fatiguing contractions (P < 0.05). Post vibration, all muscles showed higher levels of MEFs after recovery compared to the control. Our results show that near maximal isometric fatiguing contractions superimposed on vibration stimulation lead to a higher rate of fatigue development compared to the isometric contraction alone in the upper limb muscles. Results also show higher manifestation of mechanical fatigue post treatment with vibration compared to the control. Vibration superimposed on isometric contraction not only seems to alter the neuromuscular function during fatiguing efforts by inducing higher neuromuscular load but also post vibration treatment.
Data from: Muscle shortening velocity depends on tissue inertia and level of activation during submaximal contractions
In order to perform external work, muscles must do additional internal work to deform their tissue, and in particular, to overcome the inertia due to their internal mass. However, the contribution of the internal mass within a muscle to the mechanical output of that muscle has only rarely been studied. Here, we use a dynamic, multi-element Hill-type muscle model to examine the effects of the inertial mass within muscle on its contractile performance. We find that the maximum strain-rate of muscle is slower for lower activations and larger muscle sizes. As muscle size increases, the ability of the muscle to overcome its inertial load will decrease, as muscle tension is proportional to cross-sectional area and inertial load is proportional to mass. Thus, muscles that are larger in size will have a higher inertial cost to contraction. Similarly, when muscle size and inertial load are held constant, decreasing muscle activation will increase inertial cost to contraction by reducing muscle tension. These results show that inertial loads within muscle contribute to a slowing of muscle contractile velocities (strain-rates), particularly at the submaximal activations that are typical during animal locomotion.
Soft actuators that contract and elongate for 3D-printed biomimetic artificial muscles
<p>This dataset contains the results of mechanical tests performed on the GRACEs (GeometRy-based Actuators that Contract and Elongate) and the scripts used for the modelling of their contraction and elongation.</p> <p>Each subfolder contains a readme file that illustrates its content.</p>
Is Non-Cardiac Chest Pain Caused by Sustained Longitudinal Smooth Muscle Contraction?
ClinicalTrials.gov study NCT01839058. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.