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188 results for “muscle mechanics”
Figure 4 in The muscles, body wall and valve-opening mechanism of extant craniid (inarticulated) brachiopods
Figure 4. Line drawings and digital photographs illustrating cilia current flow and valve features of two species. (A) Diagram showing flow directions of dorsal mantle cilia currents. (B) Diagram of craniid valves and body (after Williams et al. 1997). (C–E) Novocrania californica. C. Cutaway drawing down midline of valves and muscle raising structures. (D, E) OU 44518a-b. Oblique photographs of dorsal and ventral valve interiors. (F–H) Novocrania japonica. (F, G) TUM 951117a. Oblique photographs of dorsal and ventral valve interiors. (H) Cutaway drawing down midline of valves and muscle raising structures. Abbreviations: a, anus; aasc, anterior adductor muscle scar; dv, dorsal valve; msp, median spike; pasc, posterior adductor muscle scar; raams, raised anterior adductor muscle scar; rp, raised pedestal; tve, thin valve extension; vmd, ventral mound; vv, ventral valve.
Data from: Bayesian estimation of muscle mechanisms and therapeutic targets using variational autoencoders
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Simple muscle-lever systems are not so simple: The need for dynamic analyses to predict lever mechanics that maximize speed
<p><span>Here we argue that quasi-static analyses are insufficient to predict the speed of an organism from its skeletal mechanics alone (i.e. lever arm mechanics). Using a musculoskeletal numerical model we specifically demonstrate that 1) a single lever morphology can produce a range of output velocities, and 2) a single output velocity can be produced by a drastically different set of lever morphologies. These two sets of simulations quantitatively demonstrate that it is incorrect to assume a one-to-one relationship between lever arm morphology and organism maximum velocity. We then use a statistical analysis to quantify what parameters are determining output velocity, and find that muscle physiology, geometry, and limb mass are all extremely important. Lastly we argue that the functional output of a simple lever is dependent on the dynamic interaction of two opposing factors: those decreasing velocity at low mechanical advantage (low torque and muscle work) and those decreasing velocity at high mechanical advantage (muscle force-velocity effects). These dynamic effects are not accounted for in static analyses and are inconsistent with a force-velocity tradeoff in lever systems.</span> <span>Therefore, we advocate for a dynamic, integrative approach that takes these factors into account when analyzing changes in skeletal levers.</span></p>
Transcriptomic Analysis Data for MSTN Mutations and Mechanisms of Muscle Hypertrophy in a New Guinea Pig Breed
<p>This dataset contains raw RNA-seq data from six guinea pig muscle samples, split into two groups:</p> <ul> <li><strong>Native guinea pigs (B1 to B3):</strong> Control group with no selective breeding.</li> <li><strong>Kuri breed guinea pigs (B4 to B6):</strong> Synthetic hybrid group selectively bred for increased muscle mass.<br>Each sample has paired-end FASTQ files (e.g., B1_1.fq.gz and B1_2.fq.gz).</li> </ul>
High Protein, Core Muscle Rehab, Muscular Electrostimulation in Prolonged Mechanical Ventilation
ClinicalTrials.gov study NCT05932134. IPD Sharing: NO. Countries: 1. Publications: 1.
Mechanical loading induces the longitudinal growth of muscle fibers via a rapamycin-insensitive mechanism
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Simple muscle-lever systems are not so simple: The need for dynamic analyses to predict lever mechanics that maximize speed
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Data from: Muscle-tendon mechanics explain unexpected effects of exoskeleton assistance on metabolic rate during walking
The goal of this study was to gain insight into how ankle exoskeletons affect the behavior of the plantarflexor muscles during walking. Using data from previous experiments, we performed electromyography-driven simulations of musculoskeletal dynamics to explore how changes in exoskeleton assistance affected plantarflexor muscle–tendon mechanics, particularly for the soleus. We used a model of muscle energy consumption to estimate individual muscle metabolic rate. As average exoskeleton torque was increased, while no net exoskeleton work was provided, a reduction in tendon recoil led to an increase in positive mechanical work performed by the soleus muscle fibers. As net exoskeleton work was increased, both soleus muscle fiber force and positive mechanical work decreased. Trends in the sum of the metabolic rates of the simulated muscles correlated well with trends in experimentally observed whole-body metabolic rate (R2=0.9), providing confidence in our model estimates. Our simulation results suggest that different exoskeleton behaviors can alter the functioning of the muscles and tendons acting at the assisted joint. Furthermore, our results support the idea that the series tendon helps reduce positive work done by the muscle fibers by storing and returning energy elastically. We expect the results from this study to promote the use of electromyography-driven simulations to gain insight into the operation of muscle–tendon units and to guide the design and control of assistive devices.
Dataset: Activation of skeletal muscle is controlled by a dual-filament mechano-sensing mechanism
<p>Steady-state and dynamic calcium dependence of force and <P2> for RLC/TNC probes in skeletal muscle. Dataset for article</p> <p>10.1073/pnas.2302837120</p>
Effect of Dry Needling on Muscle Mechanical Properties and Muscle Contractility in Latent Trigger Points
ClinicalTrials.gov study NCT04466813. IPD Sharing: NO. Countries: 1. Publications: 1.
Muscle-Related Side Effects of Statins: Functional Impact, Mechanisms, and Potential Relief With Vitamin D Supplementation
ClinicalTrials.gov study NCT01493648. IPD Sharing: Not stated. Countries: 1. Publications: 1.
NMES to Prevent Respiratory Muscle Atrophy in Mechanically Ventilated Patients
ClinicalTrials.gov study NCT03453944. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Age, Lifestyle, Muscle Mechanisms in Insulin Resistance
ClinicalTrials.gov study NCT00971594. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Effect of Foam Rolling on Muscle Mechanical Properties
ClinicalTrials.gov study NCT04210947. IPD Sharing: NO. Countries: 1. Publications: 7.
The Acute Effect of Cold Spray Application on the Mechanical Properties of the Quadriceps Muscle in Athletes
ClinicalTrials.gov study NCT04277494. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Neural Mechanisms of Muscle Control in Individuals With Knee Pain
ClinicalTrials.gov study NCT02854774. IPD Sharing: NO. Countries: 1. Publications: 2.
Assessing Diaphragm Muscle Inactivity in Mechanically Ventilated ICU Patients
ClinicalTrials.gov study NCT02434016. IPD Sharing: Not stated. Countries: 1. Publications: 8.
The Investigation of Underlying Mechanism of Lumbar Multifidus Muscle Activation Deficits
ClinicalTrials.gov study NCT05961774. IPD Sharing: YES. Countries: 1. Publications: 12.
Muscle Energy Technique and Kinesiotaping in Mechanical Sacroiliac Joint Dysfunction
ClinicalTrials.gov study NCT03940287. IPD Sharing: NO. Countries: 1. Publications: 0.
Investigation of Effects of Physiotherapy Interventions on Mechanical Properties of Muscle in Head and Neck Cancer
ClinicalTrials.gov study NCT05399953. IPD Sharing: NO. Countries: 1. Publications: 12.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.