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Genome-wide association analyses identify novel Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility
<p>The Brugada syndrome GWAS summary statistics</p> <p>Brugada syndrome is a cardiac arrhythmia disorder associated with sudden death in young adults. With the exception of <em>SCN5A</em>, encoding the cardiac sodium channel Na<sub>V</sub>1.5, susceptibility genes remain largely unknown. We performed a genome-wide association meta-analysis comprising 2,820 unrelated cases with Brugada syndrome and 10,001 controls.</p> <p> </p>
Effect of Long-Term Nitrogen Fertilization on Mycorrhizal Fungi Associated with a Dominant Grass in a Chihuahuan Desert Grassland at the Sevilleta National Wildlife Refuge, New Mexico (2005)
We studied the diversity of arbuscular mycorrhizal fungi (AMF) in a semiarid grassland and the effect of long-term nitrogen (N) fertilization on this fungal community. Root samples of Bouteloua gracilis were collected at the Sevilleta National Wildlife Refuge (New Mexico, USA) from control and N-amended plots that have been fertilized since 1995. Small subunit rDNA was amplified using AMF specific primers NS31 and AM1. The diversity of AMF was low in comparison with other ecosystems, only seven operational taxonomic units (OTU) were found in B. gracilis and all belong to the genus Glomus. The dominant OTU was closely related to the ubiquitous G. intraradices/G. fasciculatum group. N-amended plots showed a reduction in the abundance of the dominant OTU and an increase in AMF diversity. The greater AMF diversity in roots from N-amended plots may have been the result of displacement of the dominant OTU, which facilitated detection of uncommon AMF. The long-term implications of AMF responses to N enrichment for plant carbon allocation and plant community structure remain unclear.
Figures 9-14 in A new species of Clinodiplosis Kieffer (Diptera, Cecidomyiidae) associated with Cecropia sp. (Urticaceae) in Brazil
Figures 9-14. Clinodiplosiscecropiae Proença & Maia. (9) female abdomen, segments 6-8 (lateral view); (10) ovipositor (lateral view); (11) pupal exuviae: cephalic region and prothoracic spiracle (frontal view); (12) pupal exuviae: abdominal segment V (dorsal view); (13-14) sexual dimorphism on pupal exuviae: (13) male's pupal exuvia: terminal segment; (14) female'spupalexuvia: terminal segment.
Figures 1–5. Chileporter huemeri n. gen. and n in New genus and species of Yponomeutidae (Lepidoptera: Yponomeutoidea) associated with Maytenus boaria Molina (Celastraceae) from Chile, with descriptions of immature stages and natural history observations
Figures 1–5. Chileporter huemeri n. gen. and n. sp., adult. 1) Wings, dorsal view. 2) Head, side view. 3) Wing veins. Scale bar: 1 mm (1, 2, 3). 4). Sternum 2. Scale bar: 0.5 mm. 5). Tergum spiny setae. Scale bar: 0.25 mm.
Figures 12–20. Chileporter huemeri n. gen. and n in New genus and species of Yponomeutidae (Lepidoptera: Yponomeutoidea) associated with Maytenus boaria Molina (Celastraceae) from Chile, with descriptions of immature stages and natural history observations
Figures 12–20. Chileporter huemeri n. gen. and n. sp. 12–15. Adult female. Scale bar: 0.25 mm. 12) Female genitalia. 13) Ductus bursae. 14) Corpus bursae. 15) Signum. 16) Larva, dorsal view. Scale bar: 1.0 mm. 17–20. Larval structures. Scale bar: 0.20 mm. 17) Mandible. 18) Crochets. 19) Microprocesses on integument. 20) Antennae.
Fig. 1 in A new species of the genus Liljeborgia Spence Bate, 1862 (Crustacea: Amphipoda: Liljeborgiidae) associated with the burrows of the spoon worm Urechis unicinctus in the Sea of Japan
Fig. 1. Habitus of live female specimen of Liljeborgia associata sp. nov. from Vostok Bay of the Sea of Japan with geographical indication of the collection sites in the Peter the Great Bay and Posjeta Bay of the Sea of Japan.
Fig. 4 in A new species of the genus Liljeborgia Spence Bate, 1862 (Crustacea: Amphipoda: Liljeborgiidae) associated with the burrows of the spoon worm Urechis unicinctus in the Sea of Japan
Fig. 4. Liljeborgia associata sp. nov., female (LEMMI) from Vostok Bay of the Sea of Japan. a. Pereopod 3. b. Pereopod 4. c. Pereopod 5. d. Distal segments of P5. e. Pereopod 6. f. Distal segments of P6. g. Pereopod 7.
Fig. 3 in A new species of the genus Liljeborgia Spence Bate, 1862 (Crustacea: Amphipoda: Liljeborgiidae) associated with the burrows of the spoon worm Urechis unicinctus in the Sea of Japan
Fig. 3. Liljeborgia associata sp. nov., female (LEMMI) from Vostok Bay of the Sea of Japan. a. Gnathopod 1. b. Chela of Gn1. c. Gnathopod 2. d. Chela of Gn2.
Figures 9–10 in Studies on palearctic Onthophagus associated with burrows of small mammals. IV. A new Iranian species belonging to the furciceps group (Coleoptera, Scarabaeidae, Onthophagini)
Figures 9–10. Onthophagus (Paleonthophagus) psychopompus sp. n. Male, paratype (Iran, Sirdan, Qazvin prov.) and female, paratype (Iran, Saqqez, Kordestan prov.). 9 Dorsum of male 10 Dorsum of female. Photos by A. Ballerio, scanned by G. Fiumi.
Figures 1–7 in Studies on palearctic Onthophagus associated with burrows of small mammals. IV. A new Iranian species belonging to the furciceps group (Coleoptera, Scarabaeidae, Onthophagini)
Figures 1–7. Onthophagus (Paleonthophagus) psychopompus sp. n. Male, holotype, and female, allotype (Iran, Hashtgerd, Tehran prov.). 1 Male: head and pronotum, dorsal view 2 Male: head, frontal view 3 Female: head and pronotum, dorsal view 4 Female: head, frontal view 5 Parameres, lateral view 6 Parameres, dorsal view 7 Lamella copulatrix, ventral side. Drawings by I. Gudenzi.
Figure 7 in An illustrated key to powder post beetles (Coleoptera, Bostrichidae) associated with rubberwood in Thailand, with new records and a checklist of species found in Southern Thailand
Figure 7. Heterobostrychus aequalis (Waterhouse, 1884). Dorsal view of female a and male b lateral view of male elytral declivity c intercoxal process of the first abdominal ventrite d.
Figure 3 in An illustrated key to powder post beetles (Coleoptera, Bostrichidae) associated with rubberwood in Thailand, with new records and a checklist of species found in Southern Thailand
Figure 3. Dorsal views of Minthea reticulata Lesne, 1931 a Minthea rugicollis (Walker, 1858) b and Lyctoxylon dentatum (Pascoe, 1866) c.
Fig. 13 in Associations and a new species of the genus Apatidelia (Trichoptera, Apataniidae) from China
Fig. 13. Habitus of Apatidelia acuminata Leng & Yang, 1998, larva. A. Dorsal view. B. Ventral view. C. Lateral view. D. Case (ventral view). Scale bars = 1.0 mm.
Fig. 12 in Associations and a new species of the genus Apatidelia (Trichoptera, Apataniidae) from China
Fig. 12. Abdomen of Apatidelia acuminata Leng & Yang, 1998, larva. A–C. Segment I. A. Dorsal view. B. Ventral view. C. Lateral view. D. Segments IX–X and anal claw (dorsal view). Scale bar = 0.5 mm.
Fig. 11 in Associations and a new species of the genus Apatidelia (Trichoptera, Apataniidae) from China
Fig. 11. Legs of Apatidelia acuminata Leng & Yang, 1998, larva. A. Foreleg (posterior face). B. Midleg (posterior face). C. Hind leg (posterior face). Scale bar = 0.5 mm.
Fig. 9 in Associations and a new species of the genus Apatidelia (Trichoptera, Apataniidae) from China
Fig. 9. Head of Apatidelia acuminata Leng & Yang, 1998, larva. A. Dorsal view. B. Ventral view. C. Lateral view. D. Right mandible (lateral view). Scale bars: A–C = 0.5 mm; D = 0.25 mm.
Fig. 6 in Associations and a new species of the genus Apatidelia (Trichoptera, Apataniidae) from China
Fig. 6. Male genitalia of Apatidelia acuminata Leng & Yang, 1998. A. Lateral view. B. Dorsal view. C. Ventral view. Aedeagus. D. Dorsal view. E. Lateral view. Scale bar = 0.5 mm refers to all figures.
Fig. 7 in Associations and a new species of the genus Apatidelia (Trichoptera, Apataniidae) from China
Fig. 7. Female genitalia of Apatidelia acuminata Leng & Yang, 1998. A. Lateral view. B. Dorsal view. C. Ventral view. Scale bar = 0.5 mm.
Fig. 4 in Associations and a new species of the genus Apatidelia (Trichoptera, Apataniidae) from China
Fig. 4. Male genitalia of Apatidelia morsei Xu & Sun sp. nov. A. Lateral view. B. Dorsal view. C. Ventral view. Aedeagus. D. Dorsal view. E. Lateral view. Scale bar = 0.5 mm refers to all figures.
Fig. 8 in Associations and a new species of the genus Apatidelia (Trichoptera, Apataniidae) from China
Fig. 8. Head setae of Apatidelia acuminata Leng & Yang, 1998, larva. A. Dorsal view. B. Ventral view. Scale bar = 0.5 mm.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.