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8 results for “nitroso”
Annexes to the Extensive literature search report on N-nitroso compounds in food
<p>The overall purpose of this project was the identification and selection of relevant literature to gather information on chemical identification and characterisation, sources and occurrence in food as well as data on toxicokinetics and toxicity of N-nitrosocompounds in order to support the preparatory work for the human health risk assessment of this type of substances.</p>
Peroxidase-induced C-N Bond Formation via Nitroso Ene and Diels-Alder Reactions
<p>We herein provide the raw data that form the basis of the manuscript "Peroxidase-induced C-N Bond Formation via Nitroso Ene and Diels-Alder Reactions". Please find the abstract below:</p> <p>The formation of new carbon-nitrogen bonds is indisputably one of the most important tasks in synthetic organic chemistry. Here, nitroso compounds offer a highly interesting reactivity that complements traditional amination strategies, allowing for the introduction of nitrogen functionalities via ene-type reactions or Diels-Alder cycloadditions. In this study, we highlight the potential of horseradish peroxidase as biological mediator for the generation of reactive nitroso species under environmentally benign conditions. Exploiting a non-natural peroxidase reactivity, in combination with glucose oxidase as oxygen-activating biocatalyst, aerobic activation of a broad range of <em>N</em>-hydroxycarbamates and hydroxamic acids is achieved. Thus both intra- and intermolecular nitroso-ene as well as nitroso-Diels-Alder reactions are performed with high efficiency. Relying on a commercial and robust enzyme system, the aqueous catalyst solution can be recycled over numerous reaction cycles without significant loss of activity. Overall, this green and scalable C-N bond-forming strategy enables the production of allylic amides and various <em>N</em>-heterocyclic building blocks utilizing only air and glucose as sacrificial reagents.</p>
Effect of Sublingually Generated S-nitroso-N-acetylcysteine on Systemic Blood Pressure.
ClinicalTrials.gov study NCT05798481. IPD Sharing: YES. Countries: 1. Publications: 6.
INTOXIPODCAST CAP. 9. INTOXICACIONES POR ÓXIDO NITROSO
<p>INTOXICACIONES POR ÓXIDO NITROSO</p>
Replacement of nitrite in meat products by natural bioactive compounds results in reduced exposure to N-nitroso compounds: the PHYTOME project
GEO Series GSE147996. Homo sapiens. 216 samples. Type: Expression profiling by array.
Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis
GEO Series GSE14284. Homo sapiens. 24 samples. Type: Expression profiling by array.
Hltf-deletion from the TME in a CDX model of CRC reprogrammed the human transcriptome-S-nitroso-proteome to promote inflammation and redirect metastasis
GEO Series GSE161961. Homo sapiens; Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Time-series toxicogenomics analysis of N-nitroso compound exposure in Caco-2 cells
GEO Series GSE20993. Homo sapiens. 36 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.