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78 results for “novel mutant”

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ClinicalTrials.gov36/100

Oleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study

ClinicalTrials.gov study NCT03381274. IPD Sharing: YES. Countries: 3. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov32/100

iMagemHTT: FIH Evaluation of Novel Mutant Huntingtin PET Radioligands [¹¹C]CHDI-00485180-R and [¹¹C]CHDI-00485626

ClinicalTrials.gov study NCT03810898. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
geo24/100

PARP14 is a Novel Target in STAT6 Mutant Follicular Lymphoma

GEO Series GSE208031. Homo sapiens. 54 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →
geo24/100

Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia (ERRBS)

GEO Series GSE72247. Homo sapiens. 6 samples. Type: Methylation profiling by high throughput sequencing.

openGEO-OpenSep 2015View details →
geo24/100

Whole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN (RNA-Seq).

GEO Series GSE203457. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2022View details →
geo24/100

H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers

GEO Series GSE95011. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2017View details →
geo24/100

H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562]

GEO Series GSE94528. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2017View details →
geo24/100

Inhibition of NF-κB signaling by a novel siRNA sequence induces apoptosis and suppresses tumor growth in KRAS mutant colorectal cancer.

GEO Series GSE83634. Homo sapiens. 8 samples. Type: Expression profiling by array.

openGEO-OpenMar 2018View details →
geo24/100

H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6]

GEO Series GSE94999. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2017View details →
geo24/100

A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation

GEO Series GSE74729. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2016View details →
geo24/100

Targeting HER2 Exon 20 Insertion-Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

GEO Series GSE188446. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo24/100

Comparative mutant analyses reveal a novel mechanism of ARF regulation in land plants

GEO Series GSE293375. Zea mays. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2025View details →
geo24/100

Combined Inhibition of JAK/STAT Pathway and Lysine Demethylase 1 as a Novel Therapeutic Strategy in CSF3R/CEBPA Mutant Acute Myeloid Leukemia [RUX_GSK RNA-seq]

GEO Series GSE138386. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2020View details →
geo24/100

Whole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN (Pooled CRISPR Screen).

GEO Series GSE203455. Mus musculus. 1 samples. Type: Other.

openGEO-OpenSep 2022View details →
geo24/100

Evaluating an Esr1-mutant novel cell population emerging upon ERα-antagonism by single RNA-seq

GEO Series GSE205573. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo24/100

Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia

GEO Series GSE72253. Homo sapiens. 13 samples. Type: Expression profiling by array; Methylation profiling by high throughput sequencing.

openGEO-OpenSep 2015View details →
geo24/100

Asxl1 and Cebpa cooperation in AML revealed by a novel Asxl1 mutant mouse model

GEO Series GSE133314. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2020View details →
geo24/100

Causal linkage of presence of mutant NPM1 to efficacy of novel therapeutic agents against AML cells with mutant NPM1 [RNA-Seq]

GEO Series GSE227022. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo24/100

Combined Inhibition of JAK/STAT Pathway and Lysine Demethylase 1 as a Novel Therapeutic Strategy in CSF3R/CEBPA Mutant Acute Myeloid Leukemia [LSD1i ChIP-seq]

GEO Series GSE138387. Mus musculus. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2020View details →
geo24/100

HDAC5, an early osimertinib-responsive gene, is a novel therapeutic target for the drug resistance in EGFR-mutant lung adenocarcinoma cells.

GEO Series GSE283536. Homo sapiens. 4 samples. Type: Expression profiling by array.

openGEO-OpenApr 2025View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record