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1,311 results for “ocular”
Second Ocular adnexal malignancies - Histology for Histology Correlation
<p>This table presents the histology of the first primary and histology of the orbital malignancy.</p> <p>Please note that the population in this table is different from the population in the paper. The first primary in this table includes all sites including the eye and orbit.</p>
A dataset of global variations in directional solar radiation exposure for ocular research using the libRadtran radiative transfer model
<p>Directional solar photon flux density has particular relevance to eye disease research (keratitis, cataract formation, macula degeneration) because ocular components (cornea, lens, retina) experience different exposures dependent on global location, structural geometry of the eye and human behaviour (Sliney, 1997). The human macula has a field of view of ~17<strong>°</strong>, or 0.06901537 sr (Strasburger, Rentschler & Jüttner, 2011) and its cone of exposure can be modelled at a range of global locations using a radiation transfer model to estimate different directions of irradiation. This dataset provides examples of spectral radiance within the macula field of vision, calculated with the radiative transfer model libRadtran v2.0.3 (Mayer & Kylling, 2005). Three data sets are provided at different latitudes without correction for spectral ocular transmission. Unless otherwise specified, all simulations were parametrized according to local meteorological condition (altitude, pressure, temperature) and atmospheric conditions on the simulated day (aerosol optical density, water column, O<sub>3</sub> and NO<sub>2</sub> concentrations). The model was parametrized for a subject looking northward toward the ground (-15<strong>°</strong> from horizon), at a height of 170 cm above the ground.</p> <p>For each simulation, a separate file is available for each condition (latitude, time, date, see below) that includes radiance at each wavelength. Radiance values are in mW m<sup>-2</sup> nm<sup>-1</sup> sr<sup>-1</sup>.</p> <p>The technique provides future opportunity to model global exposures of different ocular components to spectral solar irradiance using information on ocular transmission, local terrain, albedo and human behaviour in order to explore their relevance in epidemiological studies of age-related eye disease.</p> <p>For each simulation, a separate file is available for each condition (latitude, time, date, see below) that includes radiance at each wavelength. Radiance values are in mW m<sup>-2</sup> nm<sup>-1</sup> sr<sup>-1</sup>.</p> <p>The technique provides future opportunity to model global exposures of different ocular components to spectral solar irradiance using information on ocular transmission, local terrain, albedo and human behaviour in order to explore their relevance in epidemiological studies of age-related eye disease.</p> <p><em>Simulation 1: </em>This data set reports the spectral radiance from 250 - 500 nm at:</p> <ul> <li>3 latitudes (61.0: Southern Finland, 50.1 Northern France, 38.0: Central Spain).</li> <li>4 dates (April 17<sup>th</sup>, July 1<sup>st</sup>, September 1<sup>st</sup>, November 6<sup>th</sup> 2019).</li> <li>24 hours.</li> <li>8 cardinal directions (every 45<strong>° </strong>from North).</li> <li>2 aerosol optical densities (0.1 and 2.5).</li> </ul> <p><em>Simulation 2: </em>This data set reports the spectral radiance from 250 - 2,500 nm at:</p> <ul> <li>3 latitudes (61.0: Southern Finland, 50.1 Northern France, 38.0: Central Spain).</li> <li>4 dates (April 17<sup>th</sup>, July 1<sup>st</sup>, September 1<sup>st</sup>, November 6<sup>th</sup> 2019).</li> <li>24 hours.</li> <li>1 cardinal direction (North).</li> <li>2 aerosol optical densities (0.1 and 2.5).</li> </ul> <p><em>Simulation 3: </em>This data set reports the spectral radiance from 250 - 500 nm at:</p> <ul> <li>1 latitude (61.0: Southern Finland).</li> <li>4 dates (April 17<sup>th</sup>, July 1<sup>st</sup>, September 1<sup>st</sup>, November 6<sup>th</sup> 2019).</li> <li>24 hours.</li> <li>9 cardinal directions (every 40<strong>° </strong>from North).</li> <li>3 bidirectional reflectance distribution functions for the ground (forest, urban, snow).</li> <li>2 tilt angles for the eye direction (0<strong>° </strong> from horizon or -15<strong>°</strong> from horizon, toward the ground).</li> </ul> <p> </p>
PLAE web app enables powerful searching and multiple visualizations across one million unified single-cell ocular transcriptomes
<p>Supplementary Data for "PLAE web app enables powerful searching and multiple visualizations across one million unified single-cell ocular transcriptomes"</p> <p> </p>
Fig. 1 A in The first autochthonous case of feline ocular thelaziosis in Austria
Fig. 1 A map showing the distribution of known cases of Thelazia callipaeda infections in Europe. Black star indicates the location where the infected cat in Austria was found
Dataset of Reaction Times for the Study of Differential Functional Changes in Visual Performance During Acute Exposure to Microgravity Analogue and their Potential Links with Spaceflight-Associated Neuro-Ocular Syndrome
<p><strong>Title</strong>: "Dataset of Reaction Times for the Study of Differential Functional Changes in Visual Performance During Acute Exposure to Microgravity Analogue and their Potential Links with Spaceflight-Associated Neuro-Ocular Syndrome"<br>Zenodo DOI: 10.5281/zenodo.11840654</p> <p><strong>Contains</strong>: simple-reaction-times-VBRHDT-data.csv<br>Dateset of SRT (simple reaction time) values to visual stimuli in different positions in visual field, binocularly observed, in a microgravity analogue study, in four body positions (vertical, horizontal, -6 deg tild, -15 deg tilt). <br>Total records contained: 3584.</p> <p><strong>Institutional Review Board Statement</strong>: The study was conducted in accordance with the Declaration of Helsinki, and approved by the Ethics Committee “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania, 14877/26.05.2023. Data was collected in SpaceMed Laboratory , CIeH (Center for Innovation and eHealth) of UMF Carol Davila Bucharest, Romania.</p> <p><strong>Citation and</strong> <strong>Detailed description:</strong> see "<em>Differential functional changes in visual performance during acute exposure to microgravity analogue and their potential links with Spaceflight-Associated Neuro-Ocular Syndrome</em>", 2024, by Iftime A, Tofolean IT, Pintilie V, Călinescu O, Busnatu S, Papacocea IR, Diagnostics ,2024; 14(17):1918. doi: 10.3390/diagnostics14171918 <br>https://pubmed.ncbi.nlm.nih.gov/39272703/</p> <p><strong>Structure</strong>: Dataset is in CSV (Comma-Separated Values) format, UTF-8 encoded, text field delimited with quotation marks, in tidy format; one row is one record from the SRT task, variables values are in columns). The first row is the variable name. The variable are:</p> <p>1) "live_row"<br>- type: integer numbers, sequential;<br>- values: the index (order) of each SRT measurement performed in a body position, by a participant (ID). The value is C-based (first measurement is "0", second measurement is "1", etc).</p> <p>2) "response_time"<br>- type: real numbers, continuous values;<br>- values: response time recorded from the participant; values in miliseconds.</p> <p>3) "target_position_x_deg"<br>- type: real numbers, categorical (4 values: +/- 18.478, +/- 0.75);<br>- values: horizontal visual angle, in visual degrees in the visual field, of the position of the stimulus. Screen coordinates are computed from "0" position, foveal fixation, positive values to the right, negative values to the left.</p> <p>4) "target_position_y_deg"<br>- type: real numbers, categorical (2 values: -0.75, -7.654);<br>- values: vertical visual angle, in visual degrees in the visual field, of the position of the stimulus. Screen coordinates are computed from "0" position, foveal fixation, positive values downward, negative values upward.<br>-Note: For the equivalent polar coordinates (as in planimetry testing) see Figure 2 of the mentioned paper. </p> <p>5) "Contrast_Weber_calibrated"<br>- type: real numbers, categorical (2 values: 50.58, 99.3);<br>- values: Measured Weber contrast of the visual stimulus shown, values in percents.</p> <p>6) "hand"<br>- type: categorical, 1 value ("right");<br>- values: hand used by the participant during SRT task.</p> <p>7) "body_position"<br>- type: categorical (4 values: "vertical (90 deg)", "horizontal (0 deg)", "inclined (-6 deg)", "inclined (-15 deg)" );<br>- values: Body position during the SRT task.</p> <p>8) "ID(anon)"<br>- type: integer number, categorical, 8 values;<br>- values: anonymized ID of the participants in the study (8 persons).</p>
The Tangential Nucleus Controls a Gravito-inertial Vestibulo-ocular Reflex
<p>Background</p> <p>Although adult vertebrates sense changes in head position by using two classes of accelerometer, at larval stages zebrafish lack functional semicircular canals and rely exclusively on their otolithic organs to transduce vestibular information.</p> <p>Results</p> <p>Despite this limitation, we find that larval zebrafish perform an effective vestibulo-ocular reflex (VOR) that serves to stabilize gaze in response to pitch and roll tilts. By using single-cell electroporations and targeted laser ablations, we identified a specific class of central vestibular neurons, located in the tangential nucleus, that are essential for the utricle-dependent VOR. Tangential nucleus neurons project contralaterally to extraocular motoneurons and in addition to multiple sites within the reticulospinal complex.</p> <p>Conclusions</p> <p>We propose that tangential neurons function as a broadband inertial accelerometer, processing utricular acceleration signals to control the activity of extraocular and postural neurons, thus completing a fundamental three-neuron circuit responsible for gaze stabilization.</p> <p>Highlights</p> <p>► The utricle and its associated circuitry drive a broadband vestibular-ocular reflex ► Linear summation of bilateral utricular signals mediates compensatory eye rotations ► Central vestibular neurons in the tangential nucleus are necessary for the VOR ► Visual and vestibular signals interact to enhance gaze stabilization</p> <ul> </ul>
An Assessment of the Ocular Toxicity of Two Major Sources of Environmental Exposure
<p>These data contain information on chemicals released in to the air from burn pits in Iraq (waste disposal areas for US military bases) and the 2023 Ohio train derailment in East Palestine. The goals of the study were to 1) predict the effects of exposure to these chemicals on the ocular surface and 2) to call attention to the relationship between environmental events and long-term damage to the surface of the eye—in particular, dry eye disease, which is a known result of workplace chemical exposures. The study employed in silico methods through the ACD Labs Percepta platform, using data from the European Chemical Inventory and the Registry of Toxic Effects of Chemical Substances to model the chemicals’ probability of ocular irritation. Variables include the names of compounds identified from the burn pits and the train derailment, along with their chemical formulas, simplified molecular input line entry system (abbreviated to SMILES), and probability of causing eye irritation.</p>
Ocular Toxoplasmosis Fundus Images Dataset
<p>The <strong>Ocular Toxoplasmosis (OT) Fundus Images Dataset</strong> contains a set of eye images collected at the <em>Hospital de Clínicas</em> and <em>Hospital General Pedriático Acosta Ñu </em>medical centers from Asunción, Paraguay.</p> <p>The dataset is used in the generation of models for automatic detection of ocular toxoplasmosis. Used as a tool for OT diagnosis, a predictive model could save time, help diagnose atypical cases and also assist ophthalmologists, being particularly useful for those with less experience.</p> <p>Dataset structure:</p> <pre><code>+-- Ocular_Toxoplasmosis_Data | +-- masks | +-- images | +-- dataset_labels.csv</code></pre> <p>The dataset contains two major folders, one with all the collected images and another one with the masks for lesions of eyes images with ocular toxoplasmosis. The dataset also includes a <strong>csv</strong> file with the labels for each image: healthy, active and inactive lesions, this two being non healthy.</p> <p>Notes about the masks: the dataset includes masks for all non healthy images (active and inactive lesions). In order to differentiate the active lesions which are less common that the inactive ones, the mask includes the suffix <strong>-a </strong>for all the masks of active lesions.</p>
FIGS. 10–17. Nopsides ceralbonus Chamberlin, male. 10. Habitus, dorsal view. 11. Same, ventral view. 12. Carapace, dorsal view. 13. Same, oblique view. 14. Same, lateral view. 15. Ocular region, dorsal view. 16. Same, anterior view. 17 in The Haplogyne Spider Genus Nopsides (Araneae, Caponiidae), with Notes on Amrishoonops
FIGS. 10–17. Nopsides ceralbonus Chamberlin, male. 10. Habitus, dorsal view. 11. Same, ventral view. 12. Carapace, dorsal view. 13. Same, oblique view. 14. Same, lateral view. 15. Ocular region, dorsal view. 16. Same, anterior view. 17. Cheliceral stridulatory file, lateral view.
Bandage Lenses in Treating Patients With Ocular Graft-Versus-Host Disease
ClinicalTrials.gov study NCT01616056. IPD Sharing: YES. Countries: 1. Publications: 1.
A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension
ClinicalTrials.gov study NCT04285580. IPD Sharing: YES. Countries: 1. Publications: 1.
A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension
ClinicalTrials.gov study NCT02636946. IPD Sharing: YES. Countries: 9. Publications: 1.
Using psychophysical performance to predict short-term ocular dominance plasticity in human adults
<p>This is the dataset reported in the manuscript "Using psychophysical performance to predict short-term ocular dominance plasticity in human adults" published in the Journal of Vision 2020;20(7):6. doi: <a href="https://doi.org/10.1167/jov.20.7.6">https://doi.org/10.1167/jov.20.7.6</a></p> <p> </p>
Measurement of ocular counter-roll using iris images during binocular fixation and head tilt
<p>All images and datas used in the study "Measurement of ocular counter-roll using iris images during binocular fixation and head tilt"</p>
Clinical characteristics of patients hospitalized for ocular chemical injuries in Shanghai from 2012 to 2017
Objective: To summarize the clinical characteristics of patients with ocular chemical injuries and evaluate their potential relationship with the visual outcome by analyzing the medical records of these patients from January 1, 2012, to December 31, 2017. Design: A retrospective case series study. Setting: Jinshan Hospital of Fudan University in Shanghai. Methods: Patient data included age, gender, occupational classification, location of ocular chemical injury, initial and final best-corrected distance visual acuity (BCDVA), intraocular pressure (IOP), nature and chemical phase, distribution and severity of chemical injury, management methods, and complications. All variables were evaluated for their potential relationship with visual outcome. Results: A total of 160 patients were hospitalized with ocular chemical injuries. The majority of the patients were factory workers and arrived at the consultation room less than 24 hours after injury. The most common ocular injury setting, classification of severity, causative chemical, chemical phase, and complications were workplace, grade Ⅱ, unknown and mixed substance, liquid, and elevated IOP, respectively. Initial BCDVA was significantly worse in the solid group than in the liquid group (P = 0.009). The risk factors for poor final BCDVA were identified as older age, poor initial BCDVA, and irrigation 24 hours after injury (P < 0.001, P < 0.001, and P = 0.011, respectively). Conclusion: We elaborate the clinical characteristics and outcomes of patients with ocular chemical injuries in Jinshan District, Shanghai. A comprehensive education program should be established and the use of protective eyewear should be promoted to prevent occupation-related ocular chemical injuries.
LRP predicts smooth pursuit eye movement onset during the ocular tracking of self-generated movements
<p>Dataset relative to the following publication:</p> <p>Chen, J., Valsecchi, M. & Gegenfurtner, K.R. (2016). LRP predicts smooth pursuit eye movement onset during the ocular tracking of self-generated movements. <em>Journal of Neurophysiology, </em>in press</p> <p>Each folder contains the data relative to one experiment and the script that was used to generate them. Please refer to "Description on data format.txt" for the usage of the data.</p> <p>Additional information can be deducted from the experimental scripts.</p>
Role of motor execution in the ocular tracking of self-generated movements
<p>Dataset relative to the following publication:</p> <p>Chen, J., Valsecchi, M. & Gegenfurtner, K.R. (2016). Role of motor execution in the ocular tracking of self-generated movements. <em>Journal of Neurophysiology, </em>DOI: 10.1152/jn.00574.2016</p> <p>Please refer to "data description.txt" for details about the data. Additional information can be deducted from the experimental scripts.</p>
Figure 1 in Ocular tentacle malformation in Deroceras reticulatum (Mollusca: Gastropoda: Agriolimacidae)
Figure 1. Deroceras reticulatum in life. Right side view (A); dorsal view (B); detail of the ocular tentacles (C-D); left side view (E). Scale bar: 2 mm.
Ocular lens morphology is influenced by ecology and metamorphosis in frogs and toads
<p><span>The shape and relative size of an ocular lens affects the focal length of the eye, with consequences for visual acuity and sensitivity. Lenses are typically spherical in aquatic animals with camera-type eyes and axially flattened in terrestrial species to facilitate vision in optical media with different refractive indices. Frogs and toads (Amphibia: Anura) are ecologically diverse, with many species shifting from aquatic to terrestrial ecologies during metamorphosis. We quantified lens shape and relative size using 179 microCT scans of 126 biphasic anuran species and tested for correlations with life stage, environmental transitions, adult habits and adult activity patterns. Across broad phylogenetic diversity, tadpole lenses are more spherical than those of adults. Biphasic species with aquatic larvae and terrestrial adults typically undergo ontogenetic changes in lens shape, whereas species that remain aquatic as adults tend to retain more spherical lenses after metamorphosis. Further, adult lens shape is influenced by adult habit; notably, fossorial adults tend to retain spherical lenses following metamorphosis. Finally, lens size relative to eye size is smaller in aquatic and semiaquatic species than other adult ecologies. Our study demonstrates how ecology shapes visual systems, and the power of non-invasive imaging of museum specimens for studying sensory evolution.</span></p>
miRNAs in primary open-angle glaucoma and ocular hypertension
<p>Glaucoma is a chronic neurodegenerative disease, which is the leading cause of irreversible blindness worldwide. As a response to high intraocular pressure, the clinical and molecular glaucoma biomarkers indicate the biological state of the visual system. Classical and uncovering novel biomarkers of glaucoma development and progression, follow-up, and monitoring the response to treatment are key objectives to improve vision outcomes. While the glaucoma imaging field has successfully validated biomarkers of disease progression, there is still a considerable need for developing new biomarkers of early glaucoma, that is, at the preclinical and initial glaucoma stages. Outstanding clinical trials and animal-model study designs, innovative technology, and analytical approaches in bioinformatics are essential tools to successfully uncover novel glaucoma biomarkers with a high potential for translation into clinical practice. To better understand the clinical and biochemical–molecular–genetic glaucoma pathogenesis, we conducted an analytical, observational, and case-comparative/control study in 358 primary open-angle glaucoma (POAG) patients and 226 comparative-control individuals to collect tears, aqueous humor, and blood to process for identifying POAG biomarkers by exploring several biological pathways, such as inflammation, neurotransmitter/neurotrophin alteration, oxidative stress, gene expression, miRNAs fingerprint and its biological targets, and vascular endothelial dysfunction. We are incredibly enthusiastic about gathering as much information as possible on POAG biomarkers to learn how this information can be used to better steer the diagnosis and therapy of glaucoma to prevent blindness in the predictable future.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.