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458 results for “parasitic infection”
A droplet digital polymerase chain reaction assay to detect rare helminth parasites infecting natural host populations (Vancouver Island 2023, University of Wisconsin Madison Laboratory colony 2024)
Helminth infections represent a significant challenge to human, livestock, and wildlife health, yet they remain relatively under-studied, especially in terms of their ecological impacts. Better understanding of how these parasites spread in wildlife populations could improve our ability to predict and manage disease transmission across various species. Traditional detection methods, such as visually identifying parasites in environmental samples or infected hosts, often fall short, especially during the early stages of infection when parasite loads are minimal. In this study, we introduce a highly sensitive and precise droplet digital PCR (ddPCR) assay that quantifies helminth DNA in aquatic habitats, focusing on the 18S rRNA gene as a marker. These data utilize the model host-parasite system between the tapeworm Schistocephalus solidus, and its cyclopoid copepod host, Acanthocyclops robustus. The molecular assays are built around creating an infection standard in the lab, where copepods were singly infected with a single tapeworm parasite. We extracted DNA from 100 infected adults and used this as a standard to translate gene copy numbers from the ddPCR reactions to actual animal values. After creating a known lab standard, we then use the generated probes and primers to detect (and quantify!) infection burdens in field samples, which include both water filter samples (eDNA) and zooplankton tows from several lakes around Vancouver Island, B.C. The data presented here include well-specific data from ddPCR runs (amplitude of individual level oil droplets in the reaction) as well as each ddPCR analysis in its entirety. In order to prove the specificity of probes and probe-primers, we include here ddPCR runs of closely related helminth species, Schistocephalus cotti and Schistocephalus pungitii. We also consider the binding to another genera of copepod, the calanoid Eurytomora. All of the data wrangling, analysis, and data visualization are included as .Rmd files in th
Data for: Prior exposure of a fungal parasite to cyanobacterial extracts does not impair infection of its Daphnia host
<p>This dataset supports the findings of the study 'Prior exposure of a fungal parasite to cyanobacterial extracts does not impair infection of its <em>Daphnia</em> host', published in Hydrobiologia (https://doi.org/10.1007/s10750-022-04889-7)</p>
Data files: Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets
<p>Scripts, preprocessed count matrices, and single-cell data objects generated in <strong>“Single-cell RNA profiling of <em>Plasmodium vivax</em><em>-</em>infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets” </strong></p>
Data for: Sequential infection of Daphnia magna by a gut microsporidium followed by a haemolymph yeast decreases transmission of both parasites
<p>This dataset supports the findings presented in:<br> <br> Manzi, F., Halle, S., Seemann, L., Ben-Ami, F., & Wolinska, J. (2021). Sequential infection of <em>Daphnia magna</em> by a gut microsporidium followed by a haemolymph yeast decreases transmission of both parasites. <em>Parasitology,</em> 1-42. doi:10.1017/S0031182021001384</p>
Data for Few studies of wild animal performance account for parasite infections: a systematic review
<p>Data from a systematic review across eight scientific journals publishing primarily studies in animal behaviour and physiology over a 5-year period to assess the proportion of studies which acknowledge, treat or control for parasite infection in their study design and/or analyses. Wild animals have parasites. This inconvenient truth has far-reaching implications for biologists measuring animal performance traits: infection with parasites can alter host behaviour and physiology in profound and sometimes counterintuitive ways. Yet, to what extent do studies on wild animals take individual infection status into account? We explored whether parasite inclusion differed between studies that are experimental versus observational, conducted in the field vs the laboratory and measure behavioural vs physiological traits. We also investigated the importance of other factors such as the journal, the year of publication, the trait category (e.g. locomotion, reproduction) measured, the vertebrate taxonomic group investigated, and the host climatic zone of origin. Our results show that parasite inclusion was generally lacking across recent studies on wild vertebrates. In over 680 filtered papers, we found that only 21.9% acknowledged the potential effects of infections on animal performance in the text, and only 5.1% of studies treated animals for infection (i.e. parasite control) or considered infection status in the statistical analyses (i.e. parasite analysis). Parasite inclusion, control and analysis were higher in laboratory compared to field studies and higher for physiological studies compared to behavioural studies but did not differ among journals, performance trait categories and taxonomic groups. Overall, our literature review suggests that parasites are sorely under-acknowledged by researchers in recent years despite growing evidence that infections can modify animal performance. Given the ubiquity of parasites in the environment, we encourage scientists to consider individual infection status when assessing performance of wild animals. We also suggest ways for researchers to implement such practices in both experimental and observational studies. </p>
Mice infected with High shedder S. mansoni parasites from cross A - cage 1 - Liver histopathology data.
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with <em>S. mansoni</em> High shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 2/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.</p>
Mice infected with High shedder S. mansoni parasites from cross A - cage 2 - Liver histopathology data.
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with S. mansoni High shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 3/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.</p> <p> </p>
Mice infected with High shedder S. mansoni parasites from cross B - cage 1 - Liver histopathology data.
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with <em>S. mansoni</em> High shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 6/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.</p>
Mice infected with Low shedder S. mansoni parasites from cross A - cage 2 - Liver histopathology data.
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with <em>S. mansoni</em> Low shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 5/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.</p>
Mice infected with Low shedder S. mansoni parasites from cross A - cage 1 - Liver histopathology data.
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with <em>S. mansoni</em> Low shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 4/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.</p>
Control mice (non-infected with S. mansoni parasites) - cage 2 - Liver histopathology data (mouse ID 2C.1 / 2C.2 / 2C.3).
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas in liver of mice (non-infected with S. mansoni parasite). These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 11.1/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area (_TRICH.czi) and (_HE.czi) files.</p>
Control mice (non-infected with S. mansoni parasites) - cage 2 - Liver histopathology data (mouse ID 2C.4 / 2C.5).
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas in liver of mice (non-infected with S. mansoni parasite). These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 11.2/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area (_TRICH.czi) and (_HE.czi) files.</p>
Mice infected with High shedder S. mansoni parasites from cross B - cage 2 - Liver histopathology data.
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with <em>S. mansoni</em> High shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 7/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.</p>
Mice infected with Low shedder S. mansoni parasites from cross B - cage 2 - Liver histopathology data.
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with <em>S. mansoni</em> Low shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 9/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.</p>
Mice infected with Low shedder S. mansoni parasites from cross B - cage 1 - Liver histopathology data.
<p>The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with <em>S. mansoni</em> Low shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 8/11).<br> Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.</p>
Dataset of host, habitat and vegetation parameters in relation to gastrointestinal parasite infections of small mammalian hosts in Madagascar
<p>The dataset contains information on the endoparasite infection status of 903 individuals of four small mammal species (<em>Microcebus murinus</em>, <em>M. ravelobensis</em>, <em>Eliurus myoxinus</em>, <em>Rattus rattus</em>) in relation to host-specific (sex, body condition, population density) and habitat-specific factors (degree of habitat fragmentation, fragment size, distance to the edge of the fragment, percentage of edge habitat, vegetation structure).</p>
Figure 1 in Exposure of the snail Potamopyrgus antipodarum to herbicide boosts output and survival of parasite infective stages
Figure 1. Mean (±SE) number of cercariae emerging per day from individual snails, P. antipodarum, exposed to either control water, low, medium or high concentrations of the herbicide glyphosate. Data are shown separately for the trematodes C. parvum (N = 6 snails for each treatment), Apatemon sp. (N = 3), and an undescribed renicolid species from two localities (Tomahawk Lagoon, N = 12; Lake Waihola, N = 9). In each case, different letters on the bars indicate mean values that are significantly different (Tukey–Kramer tests, P <0.05).
Fig. 1. a in First report on Phyllobothrium delphini infection and Crassicauda sp. parasitism resulting in osseous metaplasia in a Cuvier's beaked whale (Ziphius cavirostris) from the Brazilian region
Fig. 1. a Infected adipous tissue. Phyllobothrium delphini located in the center of the well-delimited parasitic cyst. Inset: Phyllobothrium delphini displaying a whitish coloration and shiny appearance. Bar, 2 cm b Thoracic aorta artery displaying bone metaplasia. Radiographic image highlighting the strong radiopacity, similar to bone radiopacity, observed along all the artery walls. Bar, 15 cm c Parasitic cyst located in adipose tissue. Proliferating and reacting fibrous tissue with a moderate number of lymphocytes and plasmocytes located along the parasitic cyst wall. Numerous activated macrophages and multinucleated giant cell (black arrow) are visible around the P. delphini specimen displaying a degenerated cuticle (red arrow). Insert: Hight power field of inflammatory infiltrate with lymphocytes (black arrow) and plasma cells (red arrow). d Thoracic aorta artery displaying bone metaplasia. Mature bone tissue is organized as circumferential lamellae and cement line (red arrow). Note the erythrocytes within the blood vessel and adipose tissue in the medullar region of the detected bone metaplasia. Inset: Hight power field of bone metaplasia with osteocytes allocated in lacunae (black arrow). e Parasitized kidney. Crassicauda sp. involved by reactive fibrous tissue associated with inflammatory infiltrate. f Parasitized Kidney. High power field of nephritis associated with Crassicauda sp. Note the fibrosis and inflammatory infiltrate formed by macrophages (red arrow) and plasma cells (black arrow).. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Photographs of parasites encapsulated in Cepaea nemoralis shells (appendix to the paper "Morph-dependent effect of nematode infection on host movement in the land snail *Cepaea nemoralis* (Mollusca, Gastropoda)")
<p>A set of four photographs taken of shell fragments of Cepaea nemoralis (grove snail), taken in the course of the project leading to the manuscript titled: "Morph-dependent effect of nematode infection on host movement in the land snail *Cepaea nemoralis* (Mollusca, Gastropoda)". Each photograph shows a parasite encapsulated/trapped in the shell by the snail:</p> <p>AcaRX3_3.tif: a mite (presumably Riccardoella sp.)<br> NemaBX7_1.tif, NemaBX7_3.tif, NemaRK5_2.tif: unidentified nematodes (note in the latter image, the clearly visible brown-band on yellow background pattern of the shell).</p> <p>A scale bar (0.25 mm) is overlaid on each image</p> <p> </p>
Fig. 3. A in Metazoan Parasites Infecting Xiphias Gladius From The Eastern Coast Of Algeria (Sw Mediterranean Sea)
Fig. 3. A — Pennella instructa (Wilson, 1917) attached to the host's body with Conchoderma virgatum (red star); B — section of P. instructa surrounded by connective tissue; C — general morphology of parasite P. instructa (female); D — cystic forms found into the musculature: n — neck; lh — lateral horns; t — trunk; p — plumes; (ct) — connective tissue and (pi) — P. instructa. Scale bars:, C, D = 2 cm; B— x4 = 300 Μm.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.