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19
datasets available to search
ShareScore release 0.9.0
Dataset results
19 results for “partial rescue”
MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome
GEO Series GSE69691. Danio rerio. 10 samples. Type: Expression profiling by array; Non-coding RNA profiling by high throughput sequencing.
Lithium partially rescues gene expression and enhancer activity from heterozygous knockout of AKAP11 while inducing novel differential changes [RNA-Seq]
GEO Series GSE290452. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Partial rescue of neuronal genes deregulated in CdLS by cohesin
GEO Series GSE150130. Homo sapiens; Mus musculus. 78 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Inhibition of BRD4 Partially Rescues Dilated Cardiomyopathy and Cardiac Arrhythmias in Myocyte-Specific Lamin A/C Null Mice [RNA-Seq]
GEO Series GSE142125. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Inhibition of interleukin-1 receptor-associated kinase (IRAK)-4 provides partial rescue of interleukin-1 beta induced functional and gene expression changes in equine tendon cells.
GEO Series GSE300167. Equus caballus. 10 samples. Type: Expression profiling by high throughput sequencing.
MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome [miRNA-seq]
GEO Series GSE69690. Danio rerio. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Inhibition of BRD4 Partially Rescues Dilated Cardiomyopathy and Cardiac Arrhythmias in Myocyte-Specific Lamin A/C Null Mice [ChIP-Seq]
GEO Series GSE142127. Mus musculus. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome [array]
GEO Series GSE69578. Danio rerio. 8 samples. Type: Expression profiling by array.
TMEM106B reduction or partial depletion does not rescue GRN haploinsufficiency in mouse and iPSC-derived human microglia cell models [Human iMG]
GEO Series GSE237104. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
TMEM106B reduction or partial depletion does not rescue GRN haploinsufficiency in mouse and iPSC-derived human microglia cell models.
GEO Series GSE237107. Homo sapiens; Mus musculus. 78 samples. Type: Expression profiling by high throughput sequencing.
Lithium partially rescues gene expression and enhancer activity from heterozygous knockout of AKAP11 while inducing novel differential changes [ChIP-Seq]
GEO Series GSE290454. Homo sapiens. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TAZ overexpression partially rescued the transcriptomic reprogramming triggered by MESH1 silencing
GEO Series GSE135346. Homo sapiens. 12 samples. Type: Expression profiling by array.
TMEM106B reduction or partial depletion does not rescue GRN haploinsufficiency in mouse and iPSC-derived human microglia cell models [Mouse ASO]
GEO Series GSE237105. Mus musculus. 39 samples. Type: Expression profiling by high throughput sequencing.
Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes
GEO Series GSE226064. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
TMEM106B reduction or partial depletion does not rescue GRN haploinsufficiency in mouse and iPSC-derived human microglia cell models [Mouse MG]
GEO Series GSE237106. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing.
Partial phenotypic rescue of the Sesb1 mitochondrial ANT1 disease model in Drosophila
GEO Series GSE55187. Drosophila melanogaster. 14 samples. Type: Expression profiling by array.
Inhibition of BRD4 Partially Rescues Dilated Cardiomyopathy and Cardiac Arrhythmias in Myocyte-Specific Lamin A/C Null Mice
GEO Series GSE142129. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Partial dataset related to the article: "Fibrosis Rescue Improves Cardiac Function in Dystrophin-Deficient Mice and Duchenne Patient-Specific Cardiomyocytes by Immunoproteasome Modulation".
<p>This record contains raw data related to the article: "Fibrosis Rescue Improves Cardiac Function in Dystrophin-Deficient Mice and Duchenne Patient-Specific Cardiomyocytes by Immunoproteasome Modulation".</p> <p>Abstract</p> <p>Patients affected by Duchenne muscular dystrophy (DMD) develop a progressive dilated cardiomyopathy<br> characterized by inflammatory cell infiltration, necrosis, and cardiac fibrosis. Standard<br> treatments consider the use of b-blockers and angiotensin-converting enzyme inhibitors that are<br> symptomatic and unspecific toward DMD disease. Medications that target DMD cardiac fibrosis are<br> in the early stages of development. We found immunoproteasome dysregulation in affected hearts<br> of mdx mice (murine animal model of DMD) and cardiomyocytes derived from induced pluripotent<br> stem cells of patients with DMD. Interestingly, immunoproteasome inhibition ameliorated cardiomyopathy<br> in mdx mice and reduced the development of cardiac fibrosis. Establishing the<br> immunoproteasome inhibitionedependent cardioprotective role suggests the possibility of modulating<br> the immunoproteasome as new and clinically relevant treatment to rescue dilated cardiomyopathy<br> in patients with DMD.</p>
Partial depletion of SRSF1 rescued the C9ORF72-repeat neurodegeneration-associated locomotor deficits in G4C2x36 Drosophila lines
GEO Series GSE138592. Drosophila melanogaster. 9 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.