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Dataset results
28 results for “pathway enrichment”
Summary statistics - Imputed gene associations identify replicable trans-acting genes enriched in transcription pathways and complex traits
<p>Summary statistics for all trans-acting/target gene pairs tested in our manuscript.</p> <p>Preprint available: <a href="https://doi.org/10.1101/471748">https://doi.org/10.1101/471748</a></p>
Supplementary Table S1: KEGG pathway enrichment
<p>This is a dataset excel file directly related to my manuscript (MBO3_2019_11_0405.R1). The dataset excel file is a detailed result of the KEGG pathway enrichment analysis. </p>
More soil organic carbon is sequestered through the mycelium-pathway than through the root-pathway under nitrogen enrichment in an alpine forest
<p><span>Plant roots and associated mycorrhizae exert a large influence on soil carbon (C) cycling. Yet, little was known whether and how roots and </span><span>ectomycorrhizal</span><span> extraradical mycelia differentially contribute to soil organic C (SOC) accumulation in alpine forests under increasing nitrogen (N) deposition. Using ingrowth cores, the relative contributions of the root-pathway (RP) (i.e., roots and rhizosphere processes) and mycelium-pathway (MP) (i.e., extraradical mycelia and hyphosphere processes) to SOC accumulation were distinguished and quantified in an ectomycorrhizal-dominated forest receiving chronic N addition (25 kg N ha<sup>-1</sup> yr<sup>-1</sup>). Under the non-N addition, the RP facilitated SOC accumulation, while the MP reduced SOC accumulation. Nitrogen addition enhanced the positive effect of RP on SOC accumulation from +18.02 mg C g<sup>-1</sup> to +20.55 mg C g<sup>-1</sup> but counteracted the negative effect of MP on SOC accumulation from -5.62 mg C g<sup>-1</sup> to -0.57 mg C g<sup>-1</sup>, as compared to the non-N addition. Compared to the non-N addition, the N-induced SOC accumulation was 1.62~2.21 mg C g<sup>-1</sup> and 3.23~4.74 mg C g<sup>-1</sup>, in the RP and the MP, respectively. The greater contribution of MP to SOC accumulation was mainly attributed to the higher microbial C pump (MCP) efficacy (the proportion of</span><span> increased microbial residual C to the increased SOC under N addition) in the MP (72.5%) relative to the RP (57%). The higher MCP efficacy in the MP was mainly associated with the higher fungal metabolic activity (i.e., the greater fungal biomass and N-acetyl glucosidase activity) and greater binding efficiency of fungal residual C to mineral surfaces than those of RP. Collectively, our findings highlight the indispensable role of mycelia and hyphosphere processes in the formation and accumulation of stable SOC in the context of increasing N deposition.</span></p>
Pathways enriched in downstream target genes of miRNAs associated with NT-proBNP and OPN
<p>The full set of 30 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways that were significantly enriched (FDR-adjusted p<0.01) in the predicted mRNA targets of either the OPN- or NT-proBNP-associated miRNAs; 21 of these pathways were significantly enriched in both sets of targets.</p> <p>KEGG: Kyoto Encyclopedia of Genes and Genomes; miRNAs: microRNAs; NT-proBNP: N-terminal pro <a href="http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/83873">B-type natriuretic peptide</a>; OPN: osteopontin</p>
Pathway enrichment of 5 chronic pain types
<p>Pathway enrichment analysis was performed on the phenotypes investigated in our study: chronic neck, back, hip and knee pain and chronic headaches. The VEGAS2Pathway tool was used.</p>
More soil organic carbon is sequestered through the mycelium-pathway than through the root-pathway under nitrogen enrichment in an alpine forest
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Nitrogen and phosphorus enrichment differentially affect grassland ecosystem functioning via multi-trophic pathways
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Pathway enrichments from untargeted metabolomics of plasma of Peromyscus leucopus and Mus musculus with or without LPS treatment
Open the record for dataset details and reuse information.
A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)
ClinicalTrials.gov study NCT04520269. IPD Sharing: NO. Countries: 1. Publications: 2.
Longitudinal transcriptomic analysis reveals persistent enrichment of iron homeostasis and erythrocyte function pathways in severe COVID-19 ARDS
GEO Series GSE273149. Homo sapiens. 49 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of colorectal cancer cells treated with Oil Production Waste Products (OPWPs) reveals enrichment of pathways of mitochondrial functionality
GEO Series GSE220285. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Gene set enrichment analysis and ingenuity pathway analysis of metastatic clear cell renal cell carcinoma cell line
GEO Series GSE78179. Homo sapiens. 6 samples. Type: Expression profiling by array.
Information-dependent Enrichment Analysis Reveals Time-dependent Transcriptional Regulation of the Estrogen Pathway of Toxicity
GEO Series GSE84981. Homo sapiens. 60 samples. Type: Expression profiling by array.
Metabolic pathways enriched according to ERG status are associated with biochemical recurrence in Hispanic/Latino patients with prostate cancer
GEO Series GSE216490. Homo sapiens. 95 samples. Type: Expression profiling by high throughput sequencing.
The side population enriches for leukemia propagating cell activity and Wnt pathway expression in zebrafish acute lymphoblastic leukemia.
GEO Series GSE123665. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
miR-183-5p-enriched extracellular vesicles promote the crosstalk between hepatocellular carcinoma cell and endothelial cell via SIK1/PI3K/AKT and CCL20/CCR6 signaling pathways
GEO Series GSE289187. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq analysis reveals modulation of inflammatory pathways by an enriched-triterpene natural extract in mouse and human macrophage cell lines
GEO Series GSE250471. Homo sapiens; Mus musculus. 41 samples. Type: Expression profiling by high throughput sequencing.
Altered T cell infiltration and enrichment of leukocyte regulating pathways within aged skeletal muscle are associated impaired muscle function following influenza infection
GEO Series GSE241965. Mus musculus. 154 samples. Type: Expression profiling by high throughput sequencing.
Genes related to emphysema are enriched for ubiquitination pathways
GEO Series GSE63073. Homo sapiens. 42 samples. Type: Expression profiling by array.
A Trial of Gefitinib in Combination With BKM120 in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known
ClinicalTrials.gov study NCT01570296. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.