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553 results for “patient characteristics”
Epidemiological and clinical characteristics predictive of ICU mortality of traumatic brain injury patients treated at a trauma reference hospital – A cohort study - Dataset
<p><strong>Dataset of a cohort whose summary is described below.</strong></p> <p><strong>ABSTRACT</strong></p> <p><strong>Background</strong>: Traumatic brain injury (TBI) has substantial physical, psychological, social and economic impacts, with high rates of morbidity and mortality. Considering its high incidence, the aim of this study was to identify epidemiological and clinical characteristics that predict mortality in patients hospitalized for TBI in intensive care units (ICUs). <strong>Methods</strong>: A retrospective cohort study was carried out with patients over 18 years old with TBI admitted to an ICU of a Brazilian trauma referral hospital between January 2012 and August 2019. TBI was compared with other traumas in terms of clinical characteristics of ICU admission and outcome. Univariate and multivariate analyses were used to estimate the odds ratio for mortality. <strong>Results</strong>: Of the 4816 patients included, 1114 had TBI, with a predominance of males (85.1%). Compared with patients with other traumas, patients with TBI had a lower mean age (45.3 ± 19.1 versus 57.1 ± 24.1 years, p < 0.001), higher median APACHE II (19 versus 15, p <0.001) and SOFA (6 versus 3, p < 0.001) scores, lower median Glasgow Coma Scale (GCS) score (10 versus 15, p < 0.001), higher median length of stay (7 days versus 4 days, p < 0.001) and higher mortality (27.6% versus 13.3%, p < 0.001). In the multivariate analysis, the predictors of mortality were older age (OR: 1.008 [1.002-1.015], p = 0.016), higher APACHE II score (OR: 1.180 [1.155-1.204], p < 0.001), lower GCS score for the first 24 hours (OR: 0.730 [0.700-0.760], p < 0.001), and greater number of brain injuries and presence of associated chest trauma (OR: 1.727 [1.192-2.501], p < 0.001). <strong>Conclusion</strong>: Patients admitted to the ICU for TBI were younger and had worse prognostic scores, longer hospital stays and higher mortality than those admitted to the ICU for other traumas. The independent predictors of mortality were advanced age, APACHE II score, first 24-hour GCS score, number of brain injuries and chest trauma.</p>
Single-cell proteo-transcriptomic profiling reveals altered characteristics of stem and progenitor cells in patients receiving cytoreductive hydroxyurea in early-phase chronic myeloid leukemia
<p>This repository contains CITE-seq data generated from CML stem and progenitor cells before and after hydroxyurea treatment using the BD Rhapsody Single-Cell Analysis System. </p> <p><strong><br>File descriptions:</strong></p> <p>1. RSEC-adjusted UMI count files generated using the BD Rhapsody Targeted Analysis Pipeline (v. 1.10.1):</p> <ul> <li>CartridgeS1_RSEC_MolsPerCell.csv</li> </ul> <p>2. RSEC-adjusted UMI counts for cells remaining after cell quality filtering using SeqGeq software (genes expressed vs library size):</p> <ul> <li>CartridgeS1_RSEC_MolsPerCell_postQC.csv</li> </ul> <p>3. Sample tag (sample of origin) calls for each putative cell, outputted by the BD Rhapsody Targeted Analysis Pipeline (v. 1.10.1). </p> <ul> <li>CartridgeS1_Sample_Tag_Calls.csv</li> </ul> <p> </p>
Outcome of Childhood Adrenocortical Carcinoma in Developing Countries. Supplementary Table 1: Patients' characteristics and endocrinal manifestations
<p>Outcome of Childhood Adrenocortical Carcinoma in Developing Countries. Supplementary Table 1: Patients’ characteristics and endocrinal manifestations</p>
Clinical characteristics of patients hospitalized for ocular chemical injuries in Shanghai from 2012 to 2017
Objective: To summarize the clinical characteristics of patients with ocular chemical injuries and evaluate their potential relationship with the visual outcome by analyzing the medical records of these patients from January 1, 2012, to December 31, 2017. Design: A retrospective case series study. Setting: Jinshan Hospital of Fudan University in Shanghai. Methods: Patient data included age, gender, occupational classification, location of ocular chemical injury, initial and final best-corrected distance visual acuity (BCDVA), intraocular pressure (IOP), nature and chemical phase, distribution and severity of chemical injury, management methods, and complications. All variables were evaluated for their potential relationship with visual outcome. Results: A total of 160 patients were hospitalized with ocular chemical injuries. The majority of the patients were factory workers and arrived at the consultation room less than 24 hours after injury. The most common ocular injury setting, classification of severity, causative chemical, chemical phase, and complications were workplace, grade Ⅱ, unknown and mixed substance, liquid, and elevated IOP, respectively. Initial BCDVA was significantly worse in the solid group than in the liquid group (P = 0.009). The risk factors for poor final BCDVA were identified as older age, poor initial BCDVA, and irrigation 24 hours after injury (P < 0.001, P < 0.001, and P = 0.011, respectively). Conclusion: We elaborate the clinical characteristics and outcomes of patients with ocular chemical injuries in Jinshan District, Shanghai. A comprehensive education program should be established and the use of protective eyewear should be promoted to prevent occupation-related ocular chemical injuries.
Psychological Characteristics of patients with Takotsubo Syndrome and patients with Acute Coronary Syndrome: an explorative study toward a better personalized care
<p>Database of the paper: Psychological Characteristics of patients with Takotsubo Syndrome and patients with Acute Coronary Syndrome: an explorative study toward a better personalized care</p>
Characteristics of medical marijuana dispensary patients
<p><strong>Introduction</strong>: <span>Despite the rising availability and use of medical marijuana (MM) in the U.S., little is known about the demographics, clinical characteristics, or quality of life of MM patients. This study describes the demographic characteristics and health-related quality of life (HRQoL) of MM patients who are initiating treatment in Pennsylvania.</span></p> <p><strong>Methods</strong>: Two hundred<span> adults naive to MM and referred for any of the 23 state-approved qualifying conditions were recruited at three MM dispensaries in Pennsylvania between September 2020 and March 2021. All participants consented to the study, completed semi-structured interviews that included demographic questionnaires, the Short Form-36 (SF-36), and Generalized Anxiety Disorder-7 (GAD-7), provided height and weight measurements, and allowed access to their dispensary medical records. </span></p> <p><strong>Results</strong>: <span>Participants had a mean age of 48.5 ±15.6 years, predominantly identified as female (67.5 %), and were most commonly referred for chronic pain (63.5%) and/or anxiety (58.5%). Additionally, 46.0% were living with obesity as determined by Body Mass Index (BMI). Relative to a normative sample, participants reported diminished HRQoL in several domains, most notably in role limitations due to physical health (M = 46.0 ± 42.0), role limitations due to emotional problems (M = 52.5 ± 42.3), energy and fatigue (M = 39.8 ± 20.2), and pain (M = 49.4 ± 26.0).</span></p> <p><strong>Discussion/Conclusion</strong>: <span>Patients initiating MM treatment experienced low HRQoL in multiple domains. Future studies could evaluate the relationship between HRQoL and patients' decisions to pursue MM treatment, as well as changes in HRQoL with MM use over time.</span></p>
Patient Characteristics and Cognitive vs. Behavioral Therapies for Depression
ClinicalTrials.gov study NCT04529694. IPD Sharing: NO. Countries: 1. Publications: 1.
Patient Characteristics, Treatment Patterns, and Clinical Outcomes in Patients Diagnosed With HR+/HER2 Advanced/Metastatic Breast Cancer on Palbociclib + Aromatase Inhibitor (AI) Combination Therapy
ClinicalTrials.gov study NCT04394247. IPD Sharing: NO. Countries: 1. Publications: 1.
Michigan Medicine COVID-19 Cohort: Clinical Characteristics, Inflammatory Markers and Outcomes of Patients Hospitalized for COVID-19
ClinicalTrials.gov study NCT04706533. IPD Sharing: NO. Countries: 1. Publications: 19.
Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome
ClinicalTrials.gov study NCT07366684. IPD Sharing: YES. Countries: 1. Publications: 5.
Analysis of the Interaction Between Preoperative Lifestyle and Clinical Characteristics of Cardiac Surgery Patients and Perioperative Complications
ClinicalTrials.gov study NCT06991218. IPD Sharing: NO. Countries: 1. Publications: 4.
Seprafilm in Open Abdomens: a Study of Wound and Adhesion Characteristics in Trauma Damage Control Patients
ClinicalTrials.gov study NCT01594385. IPD Sharing: NO. Countries: 1. Publications: 1.
Prospective Observational Study to Describe Characteristics and Management of Patients Treated With Denosumab (Prolia®) in Routine Clinical Practice
ClinicalTrials.gov study NCT01652690. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology
ClinicalTrials.gov study NCT03842163. IPD Sharing: NO. Countries: 10. Publications: 1.
Characteristics of Sexual Dysfunction in Patients With Lung Cancer
ClinicalTrials.gov study NCT06018376. IPD Sharing: NO. Countries: 5. Publications: 1.
Description of Characteristics, Such as Age, Previous and Concurrent Treatments, Associated Diseases, of Patients With Asthma Treated With Dupilumab (DUPIXENT)
ClinicalTrials.gov study NCT04550962. IPD Sharing: YES. Countries: 12. Publications: 0.
A Phase 4 Trial Assessing the ImPact of Residual Inflammation Detected Via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remissi
ClinicalTrials.gov study NCT02198651. IPD Sharing: YES. Countries: 14. Publications: 2.
Clinical characteristics of patients hospitalized for ocular chemical injuries in Shanghai from 2012 to 2017
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Characteristics of medical marijuana dispensary patients
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Data from: Preoperative characteristics of working-age patients undergoing total knee arthroplasty
Objective Total Knee Arthroplasty (TKA) is performed more in working-age (<65 years) patients. Until now, research in this patient population has been conducted mainly among retired (≥65 years) patients. Aim of this study was therefore to describe demographic, physical, psychological and social characteristics of working TKA patients and to subsequently compare these characteristics with retired TKA patients and the general population. Methods A cross-sectional analysis. Preoperative data of 152 working TKA patients was used. These data were compared with existing data of retired TKA patients in hospital registers and with normative values from literature on the general population. Demographic, physical, psychological and social (including work) characteristics were analyzed. Results The majority (83.8%) of working TKA patients was overweight (42.6%) or obese (41.2%), a majority (72.4%) was dealing with two or more comorbidities, and most (90%) had few depressive symptoms. Mean physical activity level was 2950 minutes per week. Compared to the retired TKA population, working TKA patients perceived significantly more stiffness and better physical functioning and vitality, were more physically active, and perceived better mental health. Compared to the general population working TKA patients perceived worse physical functioning, worse physical health and better mental health, and worked fewer hours. Conclusion This study shows that a majority of working TKA patients are overweight/obese, have multiple comorbidities, but are highly active in light-intensity activities and have few depressive symptoms. Working patients scored overall better on preoperative characteristics than retired patients, and except for physical activity scored overall worse than the general population.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.