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34 results for “per- and polyfluoroalkyl substances”
Database of alternatives to persistent, mobile and toxic (PMT) substances, and to per- and polyfluoroalkyl substances (PFAS).
<p>ZeroPM partners are continuously building a database of alternatives to persistent, mobile and toxic (PMT) substances, and to per- and polyfluoroalkyl substances (PFAS). The current version available focuses on alternatives to PFAS. The ZeroPM alternative assessment database is currently available as a beta-version. It will be continuously updated as we obtain more information on alternatives to PFAS and other PMT substances.</p> <p>For information about the database, please visit: https://zeropm.eu/alternative-assessment-database/ </p>
Foam fractionation for removal of per- and polyfluoroalkyl substances: Towards closing the mass balance
<p>This data is associated with the publication <em><span>Foam fractionation for removal of per- and polyfluoroalkyl substances: Towards closing the mass balance</span></em><span><em>:</em> </span><span><a>https://doi.org/10.1016/j.scitotenv.2023.162050. </a></span></p>
Data from: Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst
<p>Per- and polyfluoroalkyl substances (PFASs) are used in a multitude of processes and products, including nonstick coatings, food wrappers, and fire-fighting foams. These chemicals are environmentally persistent, ubiquitous, and can be detected in the serum of 98% of Americans. Despite evidence that PFASs alter adaptive immunity, few studies have investigated their effects on innate immunity. We investigated the impact of nine environmentally relevant PFASs [perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid potassium salt (PFOS-K), perfluorononanoic acid (PFNA), perfluorohexanoic acid (PFHxA), perfluorohexane sulfonic acid (PFHxS), perfluorobutane sulfonic acid (PFBS), ammonium perfluoro(2-methyl-3-oxahexanoate) (GenX), 7H-perfluoro-4-methyl-3,6-dioxaoctane sulfonic acid (Nafion byproduct 2), and perfluoromethoxyacetic acid sodium salt (PFMOAA-Na)] on one component of the innate immune response, the neutrophil respiratory burst. The respiratory burst is a key innate immune process by which microbicidal reactive oxygen species (ROS) are rapidly induced by neutrophils in response to pathogens, and defects in the respiratory burst can increase susceptibility to infection. We utilized larval zebrafish, a human neutrophil-like cell line, and primary human neutrophils to ascertain whether PFAS exposure inhibits ROS production in the respiratory burst. We observed that exposure to PFHxA and GenX suppresses the respiratory burst in zebrafish larvae and a human neutrophil-like cell line. GenX also suppresses the respiratory burst in primary human neutrophils. This report is the first to demonstrate that these PFASs suppress neutrophil function and supports the utility of employing zebrafish larvae and a human cell line as screening tools to identify chemicals that may suppress human immune function. </p>
Per- and Polyfluoroalkyl Substances in Canadian Fast Food Packaging
<p>Supporting information (open data) from Per- and Polyfluoroalkyl Substances in Canadian Fast Food Packaging</p>
Outside the Safe Operating Space of a New Planetary Boundary for Per- and Polyfluoroalkyl Substances (PFAS)
<p>Supporting information (Open Data)m for the article Outside the Safe Operating Space of a New Planetary Boundary for Per- and Polyfluoroalkyl Substances (PFAS)</p>
Supporting Information from Per- and Polyfluoroalkyl Substances in North American School Uniforms
<p>Supporting data (open data) from the publication Per- and Polyfluoroalkyl Substances in North American School Uniforms</p>
Data from: Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst
Open the record for dataset details and reuse information.
Total fluorine (TF), extractable organofluorine (EOF) and sum of per- and polyfluoroalkyl substances (ΣPFAS) in artificial turfs from Stockholm, Sweden
<p>This data is associated with the publication "Widespread Occurrence of Non-Extractable Fluorine in Artificial Turfs from Stockholm, Sweden" (https://pubs.acs.org/doi/full/10.1021/acs.estlett.2c00260) and pertains artificial turfs components sampled in Stockholm, Sweden.</p><p>The excel file details concentrations of the sum of per- and polyfluoroalkyl substances (ΣPFAS), extractable organofluorine (EOF) and total fluorine (TF) in nanogram of fluorine per gram of sample (ng F/g) of the three different components of artificial turf (backing, blades and filling).</p>
Pilot-Scale Continuous Foam Fractionation for the Removal of Per- and Polyfluoroalkyl Substances (PFAS) from Landfill Leachate
<p>This is the supplementary data for the publication '<span>Pilot-Scale Continuous Foam Fractionation for the Removal of Per- and Polyfluoroalkyl Substances (PFAS) from Landfill Leachate' (</span>https://pubs.acs.org/doi/full/10.1021/acsestwater.2c00032)</p>
Integrated Treatment of Per- and Polyfluoroalkyl Substances in Existing Wastewater Treatment Plants─Scoping the Potential of Foam Partitioning
<p><span>This</span><span> file corresponds to the publication </span><span>Integrated Treatment of Per- and Polyfluoroalkyl Substances in Existing Wastewater Treatment Plants─Scoping the Potential of Foam Partitioning</span><span>: https://doi.org/10.1021/acsestengg.3c00091 </span></p> <p> </p> <p><span>All concentrations are in ng/L and were rounded to two significant digits.</span></p> <p><span>When all</span><span> triplicates had concentrations below the LOQ, the concentration is reported as < LOQ. </span></p> <p><span>When at least one triplicate had a concentration above the LOQ, the other triplicates' concentrations were set to half the LOQ, and the average of the three is reported.</span></p> <p> </p> <p><span>Sheet names correspond to the site identifiers (Table 1 of main text).</span></p>
Per and polyfluoroalkyl substances (PFAS) in marine and anadromous species sampled in the Southern Salish Sea
Open the record for dataset details and reuse information.
Influence of grain size, organic carbon and organic matter residue content on the sorption of per-and polyfluoroalkyl substances in aqueous film forming foam contaminated soils-Implications for remediation using soil washing
<p>Supporting information from Influence of grain size, organic carbon and organic matter residue content on the sorption of per-and polyfluoroalkyl substances in aqueous film forming foam contaminated soils-Implications for remediation using soil washing</p>
Transcriptomics-based points of departure for Daphnia magna exposed to 18 per- and polyfluoroalkyl substances.
GEO Series GSE245268. Daphnia magna. 392 samples. Type: Expression profiling by high throughput sequencing.
Derivation of transcriptomics-based points of departure for twenty per- or polyfluoroalkyl substances (PFAS) using a larval fathead minnow (Pimephales promelas) reduced transcriptome assay.
GEO Series GSE246120. Pimephales promelas. 888 samples. Type: Expression profiling by high throughput sequencing.
Investigating ovarian disrupting effects of per- and polyfluoroalkyl substances
GEO Series GSE227267. Mus musculus. 44 samples. Type: Expression profiling by high throughput sequencing.
Broad Profiling of Hepatic and Immunotoxic Effects of Per- and Polyfluoroalkyl Substances (PFASs) Across Sexes and Exposure Durations in C57/BL6 Mice
GEO Series GSE303480. Mus musculus. 116 samples. Type: Expression profiling by high throughput sequencing; Other.
High-throughput Transcriptomics Screen of 137 Per- and Polyfluoroalkyl Substances (PFAS) in U-2 OS Cells
GEO Series GSE297135. Homo sapiens. 0 samples. Type: Expression profiling by high throughput sequencing.
High-throughput transcriptomics assessment of 24 per- and polyfluoroalkyl substances (PFAS) in human liver spheroids
GEO Series GSE145239. Homo sapiens. 1201 samples. Type: Expression profiling by high throughput sequencing.
Per- and Polyfluoroalkyl Substance Exposure Combined with High-Fat Diet Supports Prostate Cancer Progression
GEO Series GSE185183. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
Identifying Human Specific Adverse Outcome Pathways of Per- and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice
GEO Series GSE208636. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.