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Dataset results
9 results for “percutaneous mitral valve repair”
Pivotal Study of a Percutaneous Mitral Valve Repair System
ClinicalTrials.gov study NCT00209274. IPD Sharing: Not stated. Countries: 1. Publications: 39.
Feasibility Study of a Percutaneous Mitral Valve Repair System.
ClinicalTrials.gov study NCT00209339. IPD Sharing: Not stated. Countries: 1. Publications: 23.
Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation
ClinicalTrials.gov study NCT01920698. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Deep Sedation Instead of General Anaesthesia in Percutaneous Mitral Valve Repair Using the MitraClip® System
ClinicalTrials.gov study NCT02023762. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Percutaneous Mitral Valve Repair in Cardiogenic Shock: Mitra-Shock Study
ClinicalTrials.gov study NCT04399499. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
MERIT Study - Mistral Percutaneous Mitral Valve Repair FIM Study
ClinicalTrials.gov study NCT02948231. IPD Sharing: Not stated. Countries: 1. Publications: 0.
St. Jude Medical Percutaneous Mitral Valve Repair Study
ClinicalTrials.gov study NCT01500148. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dataset related to the article "Head to Head Comparison between Different 3-Dimensional Echocardiographic Rendering Tools in the Imaging of Percutaneous Edge-to-Edge Mitral Valve Repair"
<p>This record contains raw data related to the article "Head to Head Comparison between Different 3-Dimensional Echocardiographic Rendering Tools in the Imaging of Percutaneous Edge-to-Edge Mitral Valve Repair"</p> <p>MitraClip (MC) is the most common percutaneous treatment for severe mitral regurgitation<br> (MR). An accurate two-dimensional and three-dimensional echocardiographic (3DTEE) imaging is<br> mandatory for the optimal procedural result. Recently transillumination 3DTEE rendering (3DTr) has<br> been introduced integrating a virtual light source into the dataset and with the addition of glass effect<br> (3DGl) allows to adjust tissue transparency improving depth perception and anatomical structure<br> delineation in comparison with the standard 3DTEE (3DSt). The aim of this retrospective study in<br> 30 patients undergoing MC, was to compare 3DSt, 3DTr, and 3DGl in mitral valve (MV) evaluation<br> and procedural result assessment. 3DTEE acquisitions obtained before and after MC were processed<br> with 3DSt, 3DTr, and 3DGl rendering. Each reconstruction was scored for quality and for ability<br> to recognize MV anatomy, MR origin, clip position, dimension and grasping. Imaging quality was<br> judged good or optimal in 52%, 76%, and 96% in 3DSt, 3DTr, and 3DGl reconstructions respectively.<br> In 26/30 patients a diagnostic incremental value was found with 3DTr vs. 3DSt and in 15/26 with<br> 3DGl vs. 3DTr and 3DSt. Only 3DGl with perpendicular cropping of the clip allowed to visualize and<br> measure the grasped portion of each mitral leaflets. 3DTEE imaging during MC may be improved<br> by 3DTr and 3DGl providing a better evaluation of MV, of leaflet grasping and of residual MR jets<br> after MC.</p>
Data set from Adamo M, Grasso C, Capodanno D, Rubbio AP, Scandura S, Giannini C, Fiorelli F, Fiorina C, Branca L, Brambilla N, Bedogni F, Petronio AS, Curello S, Tamburino C. Five-year clinical outcomes after percutaneous edge-to-edge mitral valve repair: Insights from the multicenter GRASP-IT registry. Am Heart J. 2019 Nov;217:32-41. doi: 10.1016/j.ahj.2019.06.015. Epub 2019 Jul 3. PMID: 31473325.
<p>Data set from Adamo M, Grasso C, Capodanno D, Rubbio AP, Scandura S, Giannini C, Fiorelli F, Fiorina C, Branca L, Brambilla N, Bedogni F, Petronio AS, Curello S, Tamburino C. Five-year clinical outcomes after percutaneous edge-to-edge mitral valve repair: Insights from the multicenter GRASP-IT registry. Am Heart J. 2019 Nov;217:32-41. doi: 10.1016/j.ahj.2019.06.015. Epub 2019 Jul 3. PMID: 31473325.</p> <p> </p> <p>This is the abstract:</p> <p>Limited evidence is available on 5-year clinical outcomes after percutaneous edge-to-edge mitral valve repair.</p> <p><strong>Methods: </strong>The Getting Reduction of mitrAl inSufficiency by Percutaneous clip implantation in ITaly (GRASP-IT) is a multicenter registry including 304 consecutive patients undergoing Mitraclip between October 2008 and October 2013 at 4 Italian centers. Primary end point (all-cause mortality) and secondary end point (all-cause mortality or heart failure [HF] hospitalization) were evaluated up to 5 years and between 1 and 5 years.</p> <p><strong>Results: </strong>Cumulative incidence of the primary and secondary end points at 1, 2, 3, 4, and 5 years were 15.1%, 26.4%, 35.5%, 42.1%, and 47.3% and 29.1%, 41.7%, 49.8%, 56%, and 62.3%, respectively. Landmark analysis between 1 and 5 years showed an incidence of primary and secondary end point of 37.9% and 46.8%, respectively. Five-year event rates were significantly higher in patients with functional ischemic mitral regurgitation (MR) compared to other etiologies. MR recurrence and left ventricular ejection fraction <30% were associated with an increased risk of both primary and secondary end points. EuroSCORE II >5% was associated with an increased risk of 5-year mortality. Ischemic etiology of MR, baseline serum creatinine >1.5 mg/dL, chronic obstructive pulmonary disease, and previous HF hospitalizations were independent predictors of 5-year secondary end point.</p> <p><strong>Conclusions: </strong>At 5-year follow-up after Mitraclip, nearly half of patients died and almost two thirds died or were admitted for HF. MR recurrence, ischemic etiology, high comorbidity burden (ie, EuroSCORE II >5%, chronic obstructive pulmonary disease), and advanced cardiomyopathy (ie, left ventricular ejection fraction <30%, prior HF admission, creatinine >1.5 mg/dL) significantly increase the relative risk of 5-year clinical events.</p>
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International Brain Laboratory public data
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OpenNeuro
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