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zenodo40/100

PharmaCoNER corpus: gold standard annotations of Pharmacological Substances, Compounds and proteins in Spanish clinical case reports

<p><strong>Intro:</strong></p><p>The PharmaCoNER corpus (divided into train, dev and test) is a Gold Standard manually annotated dataset used for the the PharmaCoNER shared task posed at BIONLP-ST (at EMNLP). In addition, we include here the PharmaCoNER background set. It contains the train, development and test sets of the two subtasks (subtask-1 and subtask-2) with Gold Standard annotations. In addition, it contains the documents of the background set, without annotations.</p><p>The PharmaCoNER corpus consists of:</p><ul><li>Manually classified clinical case sections derived from Open access Spanish medical publications, named the Spanish Clinical Case Corpus (SPACCC).</li><li>It was manually selected by a practicing oncologist and revised by a clinical documentalist to assure that records were relevant/representative and resembled structure and content relevant to process clinical records.</li><li>The final corpus: 1000 clinical cases 16,504 sentences</li><li>The corpus contains a total of 396,988 words, with an average of 396.2 words per clinical case.</li><li>It covers a range of medical disciplines including oncology, urology, cardiology, pneumology or infections diseases, etc.</li><li>The corpus has been annotated at the mention level by experts in medicinal chemistry and pharmacology following a granular annotation scheme covering four mention types:<ul><li><i>Entity type 1 (NORMALIZABLES)</i>: mentions of chemicals that can be manually normalized to a unique concept identifier (primarily SNOMED-CT).</li><li><i>Entity type 2 (NO_NORMALIZABLES)</i>: mentions of chemicals that could not be normalized manually to a unique concept identifier.</li><li><i>Entity type 3 (PROTEINAS)</i>: mentions of proteins/genes following an adaptation of the BioCreative GPRO track annotation guidelines (includes peptides, peptide hormones &amp; antibodies).</li><li><i>Entity type 4 (UNCLEAR )</i>: cases of general substance class mentions of clinical relevance, including certain pharmaceutical formulations, general treatments, chemotherapy programs, and vaccines.</li><li>Mentions class "<i>UNCLEAR</i>" (not evaluated for the PharmaCoNER track)</li></ul></li></ul><p>&nbsp;</p><p>&nbsp;</p><p><strong>Please, cite:&nbsp;</strong></p><p>A. G. Agirre, M. Marimon, A. Intxaurrondo, O. Rabal, M. Villegas, M. Krallinger, Pharmaconer: Pharmacological substances, compounds and proteins named entity recognition track, in: Proceedings of The 5th Workshop on BioNLP Open Shared Tasks, 2019, pp. 1–10.</p><p>&nbsp;</p><p><strong>Annotation quality</strong></p><p>Inter-annotator agreement: 93% for annotation, 73% for mapping.</p><p>For more information, see the <a href="https://paperswithcode.com/paper/pharmaconer-pharmacological-substances">paper</a>.</p><p>&nbsp;</p><p><strong>Format</strong></p><p>For subtask 1 annotations are distributed in <i>Brat</i> format. (More info at Brat webpage&nbsp;https://brat.nlplab.org/standoff.html)</p><p>For subtask-2, codes are associated with each document are given in a <i>TSV</i> file with the following columns:&nbsp;</p><blockquote><p>filename&nbsp;&nbsp; &nbsp;code</p></blockquote><p>&nbsp;</p><p><strong>Shared task goal:</strong></p><p>In the two subtasks, the goal is to predict the annotations of the test files (either the ANN files or the TSV with the codes) given only the plain text files.&nbsp;</p><p>&nbsp;</p><p><strong>Resources:</strong></p><ul><li><a href="https://temu.bsc.es/pharmaconer/"><strong>Web</strong></a></li><li><a href="https://www.aclweb.org/anthology/D19-5701.pdf"><strong>Citation</strong></a><strong>:&nbsp;</strong>A. G. Agirre, M. Marimon, A. Intxaurrondo, O. Rabal, M. Villegas, M. Krallinger, Pharmaconer: Pharmacological substances, compounds and proteins named entity recognition track, in: Proceedings of The 5th Workshop on BioNLP Open Shared Tasks, 2019, pp. 1–10.</li><li><a href="https://doi.org/10.5281/zenodo.4271908"><strong>Silver Standard corpus</strong></a></li><li><a href="https://doi.org/10.5281/zenodo.3763276"><strong>Annotation guidelines</strong></a></li><li><a href="https://github.com/TeMU-BSC/PharmaCoNER-Tagger"><strong>PharmaCoNER tagger</strong></a></li><li><a href="https://www.youtube.com/watch?v=B3ZzJl5OMkY"><strong>Youtube video(general setting)</strong></a></li><li><a href="https://www.slideshare.net/MartinKrallinger/pharmaconer-pharmacological-substances-compounds-and-proteins-named-entity-recognition-track-at-bionlpost-workshop-november-4-skycity-rm-2-hong-kong-emnlp2019"><strong>Slides PharmacoNER overview talk at BIONLP-ST / EMNLP&nbsp;</strong></a></li></ul><p>For further information, please visit <a href="https://temu.bsc.es/pharmaconer/">https://temu.bsc.es/pharmaconer/</a> or email us at encargo-pln-life@bsc.es</p><p>Copyright (c) 2018 Secretaría de Estado para el Avance Digital (SEAD)</p><p>&nbsp;</p><p><strong>License</strong></p><p>This work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>.</p><p>&nbsp;</p><p><strong>Contact</strong></p><p>If you have any questions or suggestions, please contact us at:</p><p><br>- Martin Krallinger (&lt;krallinger [dot] martin [at] gmail [dot] com&gt;)</p><p><strong>Additional resources and corpora</strong></p><p>If you are interested in PharmaCoNER, you might want to check out these corpora and resources:</p><ul><li><a href="https://zenodo.org/records/7614764">DisTEMIST</a> (Corpus of disease mentions and normalization to SNOMED CT, same document collection)</li><li><a href="https://zenodo.org/records/8224056">MedProcNER </a>(Corpus of clinical procedure mentions and normalization to SNOMED CT, same document collection)</li><li><a href="https://zenodo.org/records/8413866">SympTEMIST</a> (Corpus of symptoms, signs and findings mentions and normalization, same document collection)</li><li><a href="https://zenodo.org/records/7116201">MEDDOPROF</a> (Corpus of mentions of professions, occupations and working status and normalization, different document collection with some overlapping documents)</li><li><a href="https://zenodo.org/records/8403498">MEDDOPLACE</a> (Corpus of mentions of place-related entity mentions, including departments, nationalities or patient movements etc.. and normalization, different document collection with some overlapping documents)</li><li><a href="https://zenodo.org/records/4279323">MEDDOCAN</a> (Corpus of mentions of Personal Health Identifiers (PHI), modified synthetic verions of the document collection)</li><li><a href="https://zenodo.org/records/3978041">CANTEMIST</a> (Corpus of cancer tumor morphology mentions and normalization, different document collection)</li><li><a href="https://zenodo.org/records/3837305">CodiESp</a> (Corpus of clinical case reportes with assigned clinical codes from ICD10, Spanish version, same document collection)</li><li><a href="https://zenodo.org/records/7684093">LivingNER</a> (Corpus of mentions of species, including human/family members, pathogens, food, etc.. and normalization to NCBI Taxonomy, different document collection with some overlapping documents)</li><li><a href="https://zenodo.org/records/2560344">SPACCC-POS</a> (Corpus of clinical case reports in Spanish annotated with POS-tags, same document collection)</li><li><a href="https://zenodo.org/records/2560338">SPACCC-TOKEN</a> (Corpus of clinical case reports in Spanish annotated with token-tags (word mention boundaries), same document collection)</li><li><a href="https://zenodo.org/records/2560338">SPACCC-SPLIT</a> (Corpus of clinical case reports in Spanish annotated with sentence boundary-tags, same document collection)</li><li><a href="https://zenodo.org/records/5602914">MESINESP-2</a> (Corpus of manually indexed records with DeCS /MeSH terms comprising scientific literature abstracts, clinical trials, and patent abstracts, different document collection)</li></ul>

opencc-by-4.0Nov 2020View details →
zenodo24/100

Figure 1 from: Omeragic E, Marjanovic A, Djedjibegovic J, Turalic A, Dedic M, Niksic H, Lugusic A, Sober M (2021) Prevalence of use of permitted pharmacological substances for recovery among athletes. Pharmacia 68(1): 35-42. https://doi.org/10.3897/pharmacia.68.e54581

Figure 1 Distribution of athletes of both genders by age group.

opencc-by-4.0Jan 2021View details →

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